Exam 2 pics Flashcards

1
Q
A

seen by eye
-adult roundworm helminth

seen with light microscope
-eukaryotic cell / yeast
-prokaryotic cells

seen with electron microscope
-virus

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2
Q
A

baker’s and brewer’s yeast

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3
Q
A

yeast

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4
Q
A

pseudohyphae

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5
Q
A

hyphae

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6
Q
A

hyphae fungi

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7
Q
A

yeast like fungi
-pseudohyphae of candida albicans

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8
Q
A

dimorphic fungi: histoplasma capsulatum

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9
Q
A

dimorphic fungi: histoplasma capsulatum

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10
Q
A

filamentous fungi with spores

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11
Q
A

filamentous fungi

  1. spores
  2. germination
  3. hyphae
  4. subsurface hyphae
  5. aerial hyphae
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12
Q
A

filamentous fungi: spores drop down and replication

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13
Q
A

fungal cell wall

  1. mannoproteins
  2. B-1,6-glucan & B-1,3-glucan
  3. chitin
  4. B-1,3-glucan synthase
  5. UDP-Glc
  6. chitin synthase
  7. UDP-GlcNAc
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14
Q

what is the thingy poking out ?

A

sclerotium
-pores that penetrated the developing ears of rye plant

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15
Q
A

aspergillus fungi strain

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16
Q
A

penicillium
-growing fillaments
-producing conedia (pinching off of filaments)

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17
Q

how coccidioides (dimorphic fungi) is acquired?

A

inhale spores, get deposited in lungs, lead to symptoms

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18
Q
A

ringworm

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19
Q

how does athletes foot symptoms occur?

A
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20
Q
A

xray of growth of aspergillosis development

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21
Q

** mentioned this as a hotspot ** know where it acts on

A
  1. Amphotericin (causes leaky membrane)
  2. Griseofulvin (inhibit cell division using micro tubules)
  3. Flucytosine (inhibit RNA-translation)
  4. Terbinafine, Naftifine, Amorolfine (inhibit ergosterol synthesis pathway through enzymes)
  5. Azoles (inhibit ergosterol synthesis pathway)
  6. Echinocandins (target glucan synthase enzyme = no glucan)
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22
Q

what can do this inhibiting?

A

echinocandins

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23
Q

what can do this inhibiting?

A

Azoles
-produce toxic substrate
-ergosteral synthesis wont occur

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24
Q

what can do this inhibiting?

A

Fluoridated Pyrimidines

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25
virus 1. lipoprotein envelope 2. coat (caapsid)
26
polio virus
27
adenovirus
28
tobacco mosaic virus
29
bacteriophage
30
ebola virus
31
smallpox virus
32
tobacco mosaic virus
33
adenovirus
34
influenza virus
35
bacteriophage
36
tobacco mosaic virus
37
adenovirus
38
influenza virus
39
bacteriophage
40
HIV
41
Hepatitis B
42
Ebola virus
43
Adenovirus
44
Influenza
45
Bacteriophage
46
what are the structures of virus
1. individual capsomere 2. fibres for host cell attachment 3. trianglular face
47
Adenovirus (common cold)
48
influenza 1. neuraminidase 2. hemagglutinin
49
influenza 1. neuraminidase 2. hemagglutinin 3. M1 - structure holding segmented RNA (part of capsid) 4. M2 - protein channel
50
coronavirus structure
51
ACE-2 receptor used to get into cell new one released
52
learn? lol
53
HIV 1. reverse transcriptase
54
learn the steps
55
cytomegalovirus is highest cases but least known about
56
1. bacteria 2. virus 3. parasite
57
1. Fas receptor 2. Fas ligand 3. Viral peptide 4. CD8+ killer T Cell 5. Virus-infects host cell 6. MHC-1 product 7. Ag-specific receptor 8. Lytic enzymes
58
steps virus uses to get into cell
59
What inhibits what part
1. fusion inhibitor 2. RTI, NRTI, NNRTI 3. Integrase inhibitors 4. PIs 5. Anionic polymers 6. Enfuvirtide, CD4 inhibitors, Chemokine receptor inhibitors 7. NRTIs, NNRTIs 8. Integrase inhibitors 9. PIs
60
where do the protease inhibitors inhibit?
61
where do the fusion inhibitors inhibit
fusing membranes
62
What direction are nucleotides added?
5 to 3 tide=P Side=no P
63
integrase
64
what would this look like with a neuraminidase inhibitor?
prevent host cell from leaving to replicate more
65
(protozoa) no distinct structure malaria sporozoite
66
(protozoa) flagella Giardia cell
67
(protozoa) no clear flagella amoeba
68
What protozoa is this? What are the arrows pointing to?
Trypanosomiasis -african sleeping sickness parasite multiplying in blood
69
Life cycle of malaria parasite
infected mosquito bites human sucks blood / releases parasites (some already done sexual reproduction) SPOROZOITES sporozoites reach liver HYPNOZOITES undergo multiple cyclic stages here MEROZOITES Liver releases merozoites Merozoites go to red blood cells -asexual reproduction TROPHOZOITES Trophozoites released -male and female gametes
70
How people with sickle cell anemia have tolerance to malaria symptoms
growth needs hemoglobin and CO has a lot of hemoglobin so it isnt free -no nutrient source heme can block the antigen presenting cell -no cytotoxic t cells
71
site of actions for what
a. drugs to treat acute attack (symptoms) b. drugs for radical cure -P.vivax and P. ovale only c. drugs for chemoprophylaxis d. drugs to prevent transmission