Exam 2 Patho Endocrine Flashcards

1
Q

What are the endocrine glands?

A

Pituitary, thyroid, adrenal, pancreas

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2
Q

hypothalamus

A

Coordinating center of the brain

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3
Q

hypothalamic hormones: GHRH

A

growth-hormone-releasing hormone that specifically stimulates the synthesis and release of growth hormone

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4
Q

hypo. hormones: GHIH

A

growth hormone-inhibiting hormone is a hormone that regulates the endocrine system

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5
Q

hypo. hormones: TRH

A

thyroid troponin releasing hormone that controls the release of thyroid-stimulating hormone

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6
Q

hypo. hormones: CRH

A

corticotropin-releasing hormone that controls the body’s stress response

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7
Q

hypo hormones: GnRH

A

gonadotropin-releasing hormone that controls the release of other hormones that regulate reproduction

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8
Q

hypo. hormones: PIF

A

psychological prolactin inhibiter

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9
Q

ant. pit. hormones: TSH

A

thyroid-stimulating hormone that tells your thyroid how much thyroid hormone it needs to make.

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10
Q

ant. pit. hormones: ACTH

A

adrenocorticotropic hormone that helps the body respond to stress

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11
Q

ant. pit. hormones: FSH

A

follicle-stimulating hormone that helps with sexual development and reproduction

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12
Q

ant. pit. hormones: LH

A

luteinizing hormone that regulates reproductive processes. especially during the menstrual cycle

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13
Q

Prolactin

A

controls milk production and growth of breast tissue after childbirth

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14
Q

Growth Hormone GH

A

essential for normal body growth and maturation

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15
Q

Where are the hypothalamic hormones transported to?

A

Anterior pituitary through portal vessels.

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16
Q

ADH and Oxytocin are produced where?

A

By nerve cells in the supraoptic and paraventricular in the hypothalamus.

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17
Q

Hypopituitarism

A

deficiency of pituitary hormone, not receiving O2, hypothalamus not performing as it should

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18
Q

Hyperpituitarism

A

Overproduction of pituitary hormone. Excess secretion of ACTH. Excess secretion of growth hormone

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19
Q

anterior pituitary disorders

A

Hypopituitarism, hyperpituitarism

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20
Q

posterior pituitary disorders

A

Syndrome of inappropriate ADH secretion (SIADH), DI, pituitary tumors

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21
Q

SIADH

A

results from failure of the negative feedback system that regulates the release and inhibition of ADH

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22
Q

Sheehan Syndrome

A

unable to produce any breast milk, affects menstrual cycle, egg production, metabolism, atrophy of uterus and breast tissue, and infertility in women. Leads to testicular atrophy, infertility, in men.

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23
Q

hyperprolactinemia

A

menstrual irregularities, infertility, bone loss, etc

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24
Q

Deficiency of Prolactin

A

inadequate lactation, infertility, fatigue, low BP, confusion

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25
Deficiency of Gonadotropin
infertility, irregular periods, fatigue, loss of pubic hair, decreased bone density
26
Deficiency of Thyrotropin
weight gain, fatigue, hair loss, menstrual irregularities, bradycardia
27
Deficiency of Adrenocorticotropic hormone
fatigue, weight loss, weakness, low BP
28
Posterior Pituitary disorders secrete function tumors. They secrete what?
Function hormones
29
Posterior pituitary disorders produce non functioning tumors. What do they produce?
Do not produce or secrete hormones
30
malignant posterior pituitary tumors are rare. True or false?
True
31
GH excess in adults
occurs after bones have been fused. Acromegaly
32
GH excess in children
tall stature in children, gigantism
33
What are the thyroid hormones?
Thyroxine (T4), Tri-iodothyronine (T3), thyroid hormone, calcitonin
34
hyperthyroidism
Results when tissues are exposed to high levels of circulating thyroid hormone
35
Graves disease is the result of what thyroid function disorder?
hyperthyroidism
36
Thyroid storm is the result of what thyroid function disorder?
Hyperthyroidism
37
hypothyroidism
Lack of thyroid hormone causing insufficient stimulation of metabolism and heat production
38
clinical manifestations of hyperthyroidism
goiter, flushed warm skin, fine/soft hair/nails, protrusion of one or more eyeballs, tachy/bradycardia, restlessness, weight loss
39
graves disease
Inappropriate stimulation of the thyroid gland that causes diplopia, vision loss, corneal ulceration
40
Thyroid Storm
Extreme, life-threatening form of thyrotoxicosis that results in high fever. extreme cardiovascular effects, severe CNS effects
41
Parathyroid hormone (PTH)
is secreted by the parathyroid glands. 4 parathyroid glands located on the back side of the thyroid gland
42
regulator of PTH?
Plasma calcium concentration
43
What are the catecholamines? Where are they made in the brain?
Epinephrine and norepinephrine. medulla
44
What are the peptides? Where are peptides made in the brain?
Somatostatin and substance P. medulla
45
what are the mineralocorticoids? Where are they made in the brain?
Aldosterone and corticosterone. Zona Glomerulosa.
46
what are the glucocorticoids? Where are they produced in the brain?
Cortisol and cortisone. Zona fasciculata.
47
what are the androgens? Where are they produced in the brain?
Estrogens and testosterone. Zona reticulatis
48
Androgens
essential role in K, Na, and water balance regulation. Targets intestines and sweat glands
49
cortisol
respond to stress and are essential to survival. Target body cells
50
hypofunction of adrenal cortical hormone causes...
Addison's disease, increased ACTH, low aldosterone, cortisol deficiency, congenital adrenal hyperplasia
51
hyperfunction of adrenal cortical hormone causes...
Cushing's syndrome and hyperaldosteronism
52
Addison's disease leads to
Autoimmune destruction, hypoactivity, infections
53
Cushing's syndrome leads to
excess glucocorticoid , elevated ACTH, cortisol, and glucose
54
hyperaldosteronism
excessive aldosterone. leads to electrolyte imbalances
55
manifestations of hyperaldosteronism
hypertension, weakness, muscle wasting
56
cushings syndrome characteristics
moon face, personality changes, edema, purple striae, fat deposits on face and back of shoulders, CNS irritability
57
Diabetes Insipidus
deficiency of or decreased response to ADH
58
ADH = vasopressin
regulates reabsorption of water by the kidneys
59
Low ADH response?
large amounts of urine are excreted
60
manifestations of Diabetes insipidus
polyuria, polydipsia, increased serum osmolality
61
ant. pit. excess secretion of ACTH
Cushing's disease, moon face, thin arms and legs, easy bruising, purple stretch marks, high BP
62
Thyroid dysfunction: thyroxine (T4)
a hormone produced by the thyroid gland that controls how your body uses energy
63
Thyroid dysfunctions: tri-iodothyronine (T3)
influences the activity of all the cells and tissues of your body.