Exam 2 Inflmmation Flashcards

1
Q

Mast cells release

A

Histamine

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2
Q

Histamine effect

A

Vasodilation and increased permeability

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3
Q

Vasodilation causes

A

Redness at the site of injury

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4
Q

Neutrophils

A

First to arrive from the blood stream

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5
Q

How neutrophils engulf

A

Phagocytosis

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6
Q

Opsonization

A

Where antigens are tagged so neutrophils and macrophages can easily engulf

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7
Q

Signs of inflammation

A

Heat
Redness
Swelling
Tenderness
Pain

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8
Q

Acute inflammation is caused by

A

Pathogens, damage, environmental/ chemical irritants

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9
Q

Acute inflammation cells involved

A

Neutrophils, , basophils, eosinophils, monocytes, macrophages
(Innate immune cells)

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10
Q

Acute inflammation onset starts when?

A

Immediate

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11
Q

Acute inflammation duration

A

Days

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12
Q

Acute inflammation outcome

A

Resolution, abscess formation, chronic inflammation

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13
Q

Chronic inflammation cause

A

Persistent acute inflammation
(Broken down, foreign bodies and autoimmune diseases)

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14
Q

Chronic inflammation cells involved

A

Monocytes/ macrophages, lymphocytes, plasma cells, fibroblasts
(ADAPTIVE IMMUNE CELLS)

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15
Q

Chronic inflammation onset is…

A

Delayed

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16
Q

Chronic inflammation duration

A

Months -years

17
Q

Chronic inflammation outcome

A

Tissue destruction (scaring), fibrosis

18
Q

Acute inflammation purpose

A

Adaptive immune system (turn in immune system)

Stimulate tissue healing through growth factors

19
Q

Outcome of inflammation

A

Tissue is replaced by highly fibrosis tissue that is not normal (common in persistent and autoimmune conditions)