Exam 2: Infection, Pre,Post-Op Flashcards
The body’s ability to resist disease is known as what?
Immunity
What are some reasons for wide spread distribution of emerging infections?
Global travel
Population density
Encroachment into new environments
Misuse of antibiotics
This occurs when a pathogenic organisms change in ways that decrease the ability of a drug to treat the disease
Resistance
How have HCPs contributed to the development of drug resistance microorganisms?
- Giving antibiotics for viral infections
- Succumbing to patient pressure to prescribe unnecessary antibiotic therapy
- Using inadequate drug regimens to treat infections
- Using broad spectrum or combination agents for infections that should be treated w/ first-line medications (over-treating)
How can patients contribute to the development of drug resistance microorganisms?
- Skipping doses
- Not taking antibiotics for the full duration
- Saving unused antibiotics “in case I need them later”
A viral infection is NOT treated with what?
Antibiotics
What are some patient and caregiver teaching to prevent antiobiotic resistance?
- Only take antibiotics prescribed to you
- Wash hands frequently (prevention)
- Follow directions when taking antibiotics
- Don’t request an antibiotic for flu or cold (not effective against viral)
- Finish your antibiotic (bacteria will survive, multiply, and then be harder to kill)
- Do not take left over antibiotics (may not be effective for new illness, may not be as effective if older, may not be enough doses left)
Infections in older adults may have atypical manifestations such as what?
Cognitive and behavioral changes BEFORE emergence of fever, pain, changes in lab values.
This type of precaution is used for infections spread by small particles in the air (chicken pox, measles, TB)
Airborne:
- N95
- Gown
- Gloves
- Eye protection
This type of precaution is used for infections spread in large _____ by coughing, talking, or sneezing. (Influenza and bacterial meningitis)
Droplet:
- Mask
- Gown
- Gloves
- Eye protection
This type of precaution is used for infections spread _____ (skin-to-skin or infected surfaces). C-diff, MRSA
Contact
- Gown
- Gloves
What are three functions of the immune system?
- Defense
- Homeostasis
- Surveillance
In the defense function of the immune system, what occurs?
- The body protects against invasions / prevents development of infection by attacking foreign antigens and pathogens
During the homeostasis function of the immune system, the body does what?
Digests and removes damaged cellular substances
- Goal is to have the body’s different type of cell types stay uniform and unchanged
During the surveillance function of the immune system, what are recognized and destroyed?
Mutations - recognized as foreigns cells and destroyed as result
____ are substances that elicit an immune response.
These are made of protein, found on each cell, are unique to the person so the body can recognize itself.
Antigens
Wha are the two ways immunity can be classified?
Innate and acquired
What type of immunity am i:
- Present at birth
- First line defense against pathogens
- Involves a nonspecific response: (WBC response includes neutrophils and monoctyes)
- NOT antigen specific so response can occur within minutes
- No previous exposure is needed for response to occur
Innate immunity
What type of immunity am i?:
- Development of antibodies as the result of an invasion of a foreign substance: BODY MAKES ANTIBODIES ITSELF!
- Each re-invasion results in a faster and stronger response
- May result naturally or artificially
- Immunity takes time because body is making antibodies, but is long lasting
- Memory cells present for antigen
Active acquired
What are some examples of active acquired immunity?
Vaccine
Bee sting
What type of immunity am i?:
- Host RECEIVES antibodies rather than making them
- Occurs injection w/ gamma globulin (serum antibodies)
- Has immediate effect but short lasting because people doesn’t make antigen and memory cells themselves
Passive acquired immunity
What is an example of passive acquired immunity?
Transfer of immunoglobulins across placental membrane
What is the process of the immune response to a virus?
- Virus invades body thru break in the skin and into cell
- Macrophage recognizes antigens on the surface of virus, digests it and displays virus (antigens) on its surface
- T helper cells recognizes the antigen displayed and binds to the macrophages, stimulating production of cytokines -> communication begins
- Cytokines instruct T helper cells and T cytotoxic cells to multiply. T heller cells release additional cytokines that cause B cells to multiply and make antibodies
- T cytotoxic cells and natural killer cells destroy infected body cells
- Antibodies bind to virus and mark it for destruction by macrophages
- Memory B and T cells stay behind to respond quickly if same virus attacks again
Role of mononuclear phagocytes in the immune response
- Include monocytes in blood and macrophages in the body
- Capture, process, and present antigen to lymphocyte (T or B), which stimulates the immune response