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PHRM 845 > Exam 2: HF Formulary > Flashcards

Exam 2: HF Formulary Flashcards

1
Q

Brand Name: Furosemide

A

Lasix

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2
Q

Initial Dose: Furosemide

A

20-40 mg QD or BID

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3
Q

Dose Range: Furosemide

A

20-160 mg QD or BID

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4
Q

Brand Name: Bumetanide

A

Bumex

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5
Q

Initial Name: Bumetanide

A

0.5-1 mg QD or BID

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6
Q

Dose Range: Bumetanide

A

1-2 mg QD or BID

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7
Q

Brand Name: Torsemide

A

Demadex

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8
Q

Initial Dose: Torsemide

A

10-20 mg QD

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9
Q

Dose Range: Torsemide

A

10-80 mg QD

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10
Q

Brand Name: Ethacrynic Acid

A

Edecrin

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11
Q

Initial Dose: Ethacrynic Acid

A

25-50 mg QD or BID

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12
Q

Bioavailability: Furosemide

A

50%

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13
Q

Brand Name: HCTZ

A

Esidrix, Hydrodiuril

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14
Q

Initial Dose: HCTZ

A

25 mg/day

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15
Q

Max Dose: HCTZ

A

100 mg/day

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16
Q

Brand Name: Metolazone

A

Mykrox, Zaroxolyn

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17
Q

Initial Dose: Metolazone

A

2.5 mg/day

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18
Q

Max Dose: Metolazone

A

10 mg/day

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19
Q

Brand Name: Chlorthalidone

A

Thalitone

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20
Q

Initial Dose: Chlorthalidone

A

12.5-25 mg/day

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21
Q

Max Dose: Chlorthalidone

A

50 mg/day

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22
Q

Monitoring Parameters: Diuretics

A

1-2 weeks after initiation and increase
- fluid intake
- body weight
- sign/symptoms of congestion
- JVD
- BP
- serum electrolytes
- renal function

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23
Q

Side Effects: Diuretics

A
  • hypomagnesemia
  • hypokalemia
  • volume depleation
  • azotemia
  • hyponatremia
  • postural hypertension
  • hyperuricemia
  • hyper/hypocalcemia
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24
Q

Brand Name: Enalopril

A

Vasotec

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25
Q

Target Dosing: Enalapril

A

10 mg BID

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26
Q

Brand Name: Captopril

A

Capoten

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27
Q

Target Dosing: Captopril

A

50 mg TID

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28
Q

Brand Name: Lisinopril

A

Zestril, Prinivil

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29
Q

Target Dosing: Lisinopril

A

20-40 mg QD

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30
Q

Brand Name: Benazepril

A

Lotensin

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31
Q

Brand Name: Ramipril

A

Altace

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32
Q

Target Dosing: Ramipril

A

5mg BID or 10 mg QD

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33
Q

Brand Name: Fosinopril

A

Monopril

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34
Q

Target Dosing: Fosinopril

35
Q

Brand Name: Quinapril

36
Q

Target Dosing: Quinapril

A

20-40 mg BID

37
Q

Monitoring: ACEi

A
  • volume status
  • renal function
  • potassium
  • blood pressure
  • cough
  • angioedema
38
Q

Adverse Effects: ACEi/ARB

A
  • hypotension
  • renal function insufficiency
  • hyperkalemia
  • skin rash and dysgeusia
  • cough (ace)
  • angioedema
39
Q

Brand Name: Losartan

40
Q

Target Dosing: Losartan

A

150 mg daily

41
Q

Brand Name: Valsartan

42
Q

Target Dosing: Valsartan

A

160 mg BID

43
Q

Brand Name: Candesartan

44
Q

Target Dosing: Candesartan

A

32 mg daily

45
Q

Brand Name: Sacubutril/Valsartan

46
Q

Dosing: Sacubutril/Valsartan

A

S24/V26 mg
S49/V51 mg
S97/103 mg

47
Q

Adverse Effects: Sacubitril/Valsartan

A
  • hypotension
  • elevations in SCr
  • hyperkalemia
  • contraindicated in pregnancy
48
Q

Brand Name: Bisoprolol

49
Q

Initial Dosing: Bisoprolol

A

1.25 mg daily

50
Q

Target Dosing: Bisoprolol

A

10 mg daily

51
Q

Brand Name: Carvedilol

A

Coreg/Coreg CR

52
Q

Initial Dosing: Coreg

A

IR: 3.125 mg BID
CR: 10 mg daily

53
Q

Target Dosing: Coreg

A

IR: 25-50 mg BID
CR: 80 mg daily

54
Q

Brand Name Metoprolol Succinate

55
Q

Initial Dosing: Metoprolol Succinate

A

12.5-25 mg daily

56
Q

Target Dosing: Metoprolol Succinate

A

200 mg daily

57
Q

Monitoring: Beta Blockers

A
  • BP
  • HR
  • Edema
  • fatigue or weakness
58
Q

Adverse Effects: Beta Blockers

A
  • depression
  • fatigue
  • sexual dysfunction
  • dizziness
  • bradycardia
59
Q

Brand Name: Dapagliflozen

60
Q

Target Dosing: Dapagliflozen

61
Q

Brand Name: Empagaflozin

62
Q

Target Dosing: Empagaflozin

63
Q

Brand Name: Spironolactone

64
Q

Brand Name: Eplerenone

65
Q

Adverse Effects: Aldosterone Receptor Antagonists

A

Gynecomastia
Impotence
Menstrual Irregularities

66
Q

Initial Dosing: Spironolactone

A

CrCl ≥ 50: 12.5-25 mg daily
CrCl 30-49: 12.5 mg daily or every other day

67
Q

Maintenance Dose: Spironolactone

A

CrCl≥50: 25 mg daily
CrCl 30-49: 12.5-25 mg daily

68
Q

Initial dosing: Eplerenone

A

CrCl ≥ 50: 25 mg daily
CrCl 30-49: 25 mg every other day

69
Q

Maintenance Dosing; Eplerenone

A

CrCl ≥ 50: 50 mg daily
CrCl 30-49: 25 mg daily

70
Q

Monitoring: Aldosterone Antagonists

A

renal function
potassium
(within 3 days-1week after any change or addition, diseases, or acute illness that may influence potassium concentration)

71
Q

Adverse Effects: SGLT2

A

volume depletion
KTA in DM
Hypoglycemia
Infection Risk

72
Q

Monitoring: SGLT2

A

signs of hypoglycemia
renal function
electrolytes

73
Q

Brand Name: ISDN/Hydralazine

74
Q

Initial Dosing: ISDN/Hydralazine

A

20/37/5 mg TID

75
Q

Target Dosing: ISDN/Hydralazine

A

40/75 mg TID

76
Q

Adverse Effects: ISDN/Hydralazine

A

headache
nausea
flushing
dizziness
tachycardia
lupus-like syndrome
hypotension
increaed HR
myocardial ischemia
fluid retention

77
Q

Brand Name: Ivabrandine

78
Q

Dosing: Ivabrandine

A

2.5 mg BID

adjust q2weeks based on HR

Max 7.5 mg BID

79
Q

Adverse Effects: Ivabrandine

A

fetal toxicity
atrial fibrillation
bradycardia and conduction disturbances

80
Q

Brand Name: Digoxin

81
Q

Dosing: Digoxin

A

0.125-0.25 mg daily

82
Q

Adverse Effects: Digoxin

A

anorexia, n/v, abdominal pain
visual disturbances
fatigue, weakness, dizziness, headache, confusion, delirium, psychosis

AV block
AV junctional escape arrhythmias,
junctional tachycardia
atrial arrhythmias
sinus bradycardia

83
Q

Monitoring

A

Serum digoxin levels: 0.5-0.9 ng/mL

PHRM 845 (14 decks)

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