Exam 2 diseases

Question 1

What type of hypersensitivity involves IgE antibodies?

Answer 1

Type 1

immediate

Question 2

What type of hypersensitivity involves IgG and IgM antibodies binding to a cell surface?

Answer 2

Type 2

antibody mediated

Question 3

What type of hypersensitivity involves IgG and IgM circulating complexes?

Answer 3

Type 3

immune complex mediated

Question 4

Antibody against TSH receptor on thyroid epithelial cell will stimulate thyroid hormone production without the correct ligand

Answer 4

Grave’s disease

Type 2

Question 5

Antibody bound to receptors on muscles prevents acetylcholine coming from nerve endings from binding

Answer 5

myasthenia gravis

Type 2

Question 6

Autoimmune hemolytic anemia

Answer 6

type 2

Question 7

autoimmune thrombocytopenic purpura

Answer 7

type 2

Question 8

pemphigus vulgaris

Answer 8

type 2

Question 9

vasculitis caused by ANCA

Answer 9

type 2

Question 10

goodpasture’s syndrome

Answer 10

type 2

Question 11

acute rheumatic fever

Answer 11

type 2

Question 12

insulin resistant diabetes

Answer 12

type 2

Question 13

pernicious anemia

Answer 13

type 2

Question 14

systemic lupus

Answer 14

type 3

Question 15

polyarteritis nodosa

Answer 15

type 3

Question 16

poststreptococcal glomerulonephritis

Answer 16

type 3

Question 17

serum sickness

Answer 17

type 3

Question 18

What type of hypersensitivity involves Cd4 and Cd8?

Answer 18

Type 4

T-cell mediated

Question 19

granulomatous

Answer 19

type 4

Question 20

systemic lupus erythmatosis

Answer 20

type 3

Question 21

rheumatoid arthritis

Answer 21

type 4

Question 22

multiple sclerosis

Answer 22

type 4

Question 23

type 1 diabetes

Answer 23

type 4

Question 24

inflammatory bowel disease

Answer 24

type 4

Question 25

autoimmune myocarditis

Answer 25

type 4

Question 26

allograft rejection

Answer 26

type 4

Question 27

immunodeficiency

Answer 27

increased suseptibility to infection

Question 28

immunodeficiencies and cancer

Answer 28

increased susceptibility to certain types

Question 29

ICOS-common variable immunodeficiency

Answer 29

most common human immunodeficiency

defected gene in activated T cell -> helper T cell differentiation

Question 30

CD40/CD40L mutations

Answer 30

required for class switch of antibody
deficiency: hyper IgM syndrome
no class switch happening..
B cells yes but no antibodies