Exam 2- Diabetes Obesity Substance Abuse Flashcards

1
Q

Patients with DM need what to start a safe pregnancy?

A
  • HBA1c less than 7%
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2
Q

a patient with DM and is pregnant is consider what?

A

A high risk pregnancy

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3
Q

what trimester is GDM usually diagnosed in pregnant women?

A

usually in the 2nd or 3rd trimester

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4
Q

Pregnancy is a diabetogenic state.. meaning?

A

meaning that pregnancy can cause diabetes

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5
Q

What can a pt with GDM do to increase their good outcome in their pregnancy?

A

Well managed diabetes can result in the same outcome as other pregnant women.
most important in pt w GDM

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6
Q

Current DM classification system with pregnancy

A
  • Pregestational diabetes
  • Type 1
  • Type 2:
  • Gestational diabetes
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7
Q

Pregestational diabetes

A

Pregestational diabetes – known prior to pregnancy

  • Type 1: Absolute insulin deficiency due toautoimmune
    beta cell destruction.
  • Type 2: Insulin resistance or deficiency due to a
    progressive loss of beta cell insulin secretion frequently on the background of insulin resistance.
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8
Q

Gestational diabetes

A

Gestational diabetes – diagnosed during
pregnancy
- any degree of glucose intolerance
with the onset or recognition during pregnancy.

  • Usually diagnosed in the second or third trimester of pregnancy (when the placenta is fully functioning and can release hormones that cause insulin resistance)
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9
Q

Gestational Diabetes-
pathophysiology

A

*Existence of pancreatic beta cell dysfunction
prior to pregnancy.

*Increased insulin resistance

  • Due to diabetogenic hormones secreted by the placenta:
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10
Q

Diabetogenic hormones secreted by the placenta:

A

*Growth hormone
*Human placental lactogen
*Progesterone
*Corticotropin releasing hormone

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11
Q

DM Complications in Pregnancy

A
  • Macrosomia
  • big baby + can cause birthing problems
    -risk of c/s
  • Birth trauma (shoulder dystocia)
  • Hypoglycemia
  • d/t N/V
  • Maternal complications included
    preeclampsia and cesarean birth.
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12
Q

Screening: in pts with GDM

A
  • Risk analysis of all pregnancies at 1st
    prenatal visit **
  • Additional screening again at 24-28 weeks gestation (glucose tolerance testing)
  • One or more abnormal values confirm a diagnosis of gestational diabetes.
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13
Q

Pregestational Diabetes: preconception counseling includes what?

A
  • Management of diabetes
  • HBA1c less than 7%
  • Identify and evaluate long-term
    complications
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14
Q

Pregestational Diabetes: Poor glycemic control leads to?

A
  • Birth defects
  • Macrosomia complications
  • Congenital malformations (renal, cardiac,
    skeletal, and CNS). These defects occur before 8 weeks gestation

**so preconception
counseling is crucial **
Have glucose management prior to pregnancy.

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15
Q

Care during pregnancy + main focus on ?

A
  • Nutritional management
  • Physical Activity
  • Pharmacologic Therapy

**Focus is on tight glucose control! **

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16
Q

Pharmacologic Therapy used when in GDM pts?

A

If nutrition and exercise is not adequate alone

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17
Q

Oral medications used as tx of GDM

A

*People tend to manage better with oral so standard of care may be changing to oral *

*Glyburide (DiaBeta) & Metformin
- both do not
cross the placenta and cause fetal and
neonatal hypoglycemia.

18
Q

ACOG still recommends what to be used as the first line therapy to control glucose levels?

A

insulin be used as a
first-line therapy to control glucose levels rather than oral agents.

19
Q

Insulin requires what interventions?

A
  • Frequent blood glucose measurements
    are necessary

-insulin dosage
adjusted on levels.

20
Q

Fetal well being screenings with a diabetic client

A

Fetal well being:
- NST (nonstress test)
- BPP
- Ultrasound for
size (of baby)

21
Q

Care of the diabetic client + birth plan

A

Determining the best time for birth (may
be need for medical induction of labor.

22
Q

Care of the diabetic client during labor

A
  • Monitor glucose levels every 1-2 hours
  • Maintain below 110 mg/dL
  • Insulin requirements d/t the drop after birth-
    hypoglycemia
23
Q

Care of the diabetic client after delivery

A
  • Glycemic abnormalities of GDM usually resolve.
  • Diagnosis of GDM puts women at risk for future type 2 diabetes. 50% increased risk
  • Future screening and prevention efforts
24
Q

Care of the diabetic client: education

A
  • Dietary changes
  • Glucose monitoring
  • Exercise
  • Medication
25
Diabetic patient screenings for both mom and baby to be done throughout the pregnancy
* Urine checks, kidney function, eye exams, HbA1c every 4-6 weeks * Fetal surveillance: Ultrasound (fetal growth, activity, amniotic fluid volume, BPP, NST
26
Why does having GDM affect the baby's size?
1. the mother's blood brings extra glucose to the fetus 2. fetus then makes more insulin to handle extra glucose 3. That extra glucose then gets stored as fat + fetus becomes larger than normal
27
GDM Changing insulin needs with pregnancy: 1st trimester
- insulin needs reduced; prone to hypoglycemia; N&V complicates situation
28
GDM Changing insulin needs with pregnancy: 2nd trimester
- increased needs; hyperglycemia leads to ketonemia; exaggerated ketones respond to caloric restriction
29
GDM Changing insulin needs with pregnancy: 3rd trimester
marked increase of insulin needs; hyperglycemia leading to ketonemia
30
GDM Changing insulin needs with pregnancy: labor + postpartum
decreased needs; hypoglycemia
31
Provider Management of the Pre-gestational Diabetic Women
* Referral to perinatologist and/or endocrinologist (high risk pregnancy specialists) * Regular visits with nutritionist * Hgb A1C every trimester * Fetal Echocardiogram * Level II ultrasound * Ophthalmologist * Baseline kidney and liver function tests with 24 hour urine as indicated * Usual prenatal labs with thyroid panel * Adjust medications as needed
32
Multidisciplinary approach of the Pre-gestational Diabetic Women
* Regular visits with nutritionist * Hgb A1C every trimester * Fetal Echocardiogram * Level II ultrasound * Ophthalmologist * Baseline kidney and liver function tests with 24 hour urine as indicated * Usual prenatal labs with thyroid panel * Adjust medications as needed
33
Risks/complications of a diabetic pregnant client
* Poor glycemic control leads to increased incidence of early pregnancy loss - Infections more common - Stillbirth significant risk * Congenital anomalies more common with diabetic pregnant women -Macrosomia occurs in 40-50% of all diabetic pregnancies * Poor glycemic control later in pregnancy leads to vascular disease * Polyhydramnios occurs 10 times more often
34
Obesity defined as a BMI of ?
30 kg/m2 or more *high risk pt*
35
Underweight: BMI
Underweight: BMI<18.5
36
Normal weight BMI
Normal weight: BMI=18.5-24.9
37
Overweight BMI
Overweight: 25-29
38
Severely obese BMI
Severely obese: BMI>40
39
Risk w obesity
* GDM * Hypertension * Thromboembolism * Preeclampsia * Preterm labor and birth * Fetal macrosomia * Depression * Fighting infection * Stillbirth * Cesarean birth * Early pregnancy loss * PP hemorrhage * Maternal mortality * Abnormal labor patterns-use of pitocin ****
40
Obese mothers more likely to have what kind of births?
Augmentation of labor Up to 3X higher rate of cesarean - c/s: prolonged operation time, increased blood loss, infection, DVT
41
Commonly Abused Substances
* Alcohol-Fetal alcohol spectrum disorder (FASD) * Sedatives * Nicotine * Caffeine * Marijuana * Opiates and Narcotics (neonatal abstinence syndrome (NAS) * Methamphetamines * Cocaine * Prescription Drug Misuse