Exam 2 Coronary Artery Disease Flashcards
Abnormal accumulation of lipid, or fatty substances, and fibrous tissue in lining of arterial blood vessel walls
Block and narrow vessels- reduce blood flow to heart muscle
Progresses over many years- build up of plaque narrowing walls
Atherosclerotic lesions most often occur where vessels branch
Atherosclerosis
Abnormal ______________of lipid, or fatty substances, and _________tissue in lining of arterial blood vessel walls
Abnormal accumulation of lipid, or fatty substances, and fibrous tissue in lining of arterial blood vessel walls
Block and narrow vessels- __________blood flow to heart ______
Block and narrow vessels- reduce blood flow to heart muscle
Progresses over ______years- build up of plaque _________walls
Progresses over many years- build up of plaque narrowing walls
Atherosclerotic ________most often occur where ________branch
Atherosclerotic lesions most often occur where vessels branch
Lipids and fatty tissues build up and narrow and reduce blood flow to the heart this is what causes systems like angina or they don’t have an s/s and will come in and have an MI
Plaque buildup in the vessels
Most will have symptoms and take meds for angina and then have an MI
Atherosclerosis
If thrombus forms and obstructs blood flow leads to _____ coronary syndrome which may lead to MI
If thrombus forms and obstructs blood flow leads to Acute coronary syndrome which may lead to MI
According to site and degree of narrowing as well as obstruction of blood flow
Blood flow decrease is usually progressive causing inadequate blood supply to heart muscle- Ischemia- causes Angina Pectoris
Angina is usually caused by significant atherosclerosis
If blood supply decrease is enough and for long enough irreversible damage and cell death may occur.
Over time damaged heart tissue is replaced by scar tissue and there are levels of dysfunction.
May result in low cardiac output and heart failure may occur
Decrease in blood supply may even cause heart to abruptly stop beating (sudden cardiac death)
Clinical manifestations
According to site and _______ of narrowing as well as __________ of blood flow
According to site and degree of narrowing as well as obstruction of blood flow
Blood flow decrease is usually ___________causing inadequate blood supply to heart muscle- Ischemia- causes ________Pectoris
Blood flow decrease is usually progresses causing inadequate blood supply to heart muscle- Ischemia- causes Angina Pectoris
_________is usually caused by significant atherosclerosis
Angina is usually caused by significant atherosclerosis
If blood supply ________ enough and for long enough _____________ damage and cell death may occur.
If blood supply decrease is enough and for long enough irreversible damage and cell death may occur.
Over time __________heart tissue is replaced by ____ tissue and there are levels of dysfunction.
Over time damaged heart tissue is replaced by scar tissue and there are levels of dysfunction.
May result in ________cardiac output and heart failure may occur
May result in low cardiac output and heart failure may occur
____________in blood supply may even cause heart to abruptly stop beating (sudden cardiac death)
Decrease in blood supply may even cause heart to abruptly stop beating (sudden cardiac death)
Chest pain cuz blood flow is decreased
Angina is caused by insignificant buildup
Once tissues dies it will not work anymore
Heart failure my occur with atherosclerosis
Clinical manifestations
Most common- chest pain
Some are totally asymptomatic
May present with varying sx other than chest pain- epigastric distress, pain in jaw, left arm
Dyspnea
Nausea, palpitations, numbness
May just have sudden cardiac event
Clinical manifestations for not getting enough oxygen to the heart
Clinical manifestations for not getting enough oxygen to the heart
Most common- chest pain
Some are totally asymptomatic
May present with varying sx other than chest pain- epigastric distress, pain in jaw, left arm
Dyspnea
Nausea, palpitations, numbness
May just have sudden cardiac event
Widow maker – no s/s and then they have a mi and ppl don’t come back
Some are asymptomatic
Elderly will have different signs
Clinical manifestations for not getting enough oxygen to the heart
Family history- woman before 65 or man before 55
Increasing age
Gender (men earlier than women)
Race (higher in African American)
Risk factors Non modifiable:
Risk factors
Non modifiable:
Family history- woman before 65 or man before 55
Increasing age
Gender (men earlier than women)
Race (higher in African American)
Hyperlipidemia
Tobacco use
Diabetes
HTN
Obesity
Physical inactivity
Metabolic syndrome
Alcohol
Modifiable Risk factors