Exam 2 Ch. 5 Study Guide Questions Flashcards

1
Q

Name 3 types of epidermal cells and their functions.

A

Stratified squamous epithelium tissue including:
1. Keratinocytes - make keratin, waterproofing and strengthening protein 2. Melanocytes - make melanin, pigment protein protects from UV light
3. Langerhans cells - immune function
4. Merkel cells/discs - light touch sensory receptor

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2
Q

Name the 5 strata from top to bottom of the epidermis. Which layer contains stem cells?

A
  1. Corneum
  2. Granulosum
  3. Spinosum
  4. Lucidum - palms, fingertips and soles only for extra wear and tear
  5. Basale - stem cells divide and fill above for growth and repair
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3
Q

In which dermal layer are Meissner’s corpuscles found? What do they do?

A

Papillary layer of dermis - touch/pressure receptors

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4
Q

Name two pigment proteins responsible for skin color.

A

Melanin (main) and carotene (absorbed)

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5
Q

What are the three layers, from outside to in, of any hair?

A

Cuticle, cortex, medulla

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6
Q

Which part of the hair follicle contains blood vessels and receives nutrients at the base of the hair?

A

Papilla - blood vessels/capillaries at the base called hair bulb

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7
Q

How does Rogaine work in stimulating hair growth?

A

Vasodilation to improve blood flow through capillary bed of papilla.

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8
Q

Where do you find hair follicle free nerve endings?

A

Around the follicle - gives hair touch sensation

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9
Q

When your hair “stands on end” or you have “goosebumps” it is due to:

A

Arrector pili muscle

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10
Q

What is brown hair color due to? How about blonde or grey?

A

Brown/black - more melanin
Blonde - less melanin
Grey - lack of melanin

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11
Q

What are the functions of sebaceous glands?

A

Secrete oil called sebum

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12
Q

What is found in sebum?

A

Lipids - triglycerides, cholesterol

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13
Q

Contrast eccrine and apocrine sudoriferous glands. Which opens to the epidermis? Name three substances found in sweat.

A

Eccrine - open directly onto skin surface through pores exiting epidermis, make sweat through exocytosis mostly (water, salts, urea) for cooling

Apocrine - active at puberty, open into hair follicle, mix of organic compounds, pinch off part of cell so mix includes lipids, secretion can be behavioral (anxiety)

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14
Q

Which glands make ear wax? How is it protective?

A

Ceruminous glands - thick wax inhibits microbial growth and penetration (ear canal)

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15
Q

Following the steps of the negative feedback mechanism, what happens to the skin to cool the body in thermoregulation?

A

Thermoreceptors send signal to hypothalamus which directs effectors in skin. Sweat glands sweat to create evaporative cooling on skin surface. Blood vessels in dermis near surface vasodilate (increase diameter/flow) to release heat to air.

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16
Q

How is Vitamin D activated in the skin? Which organs are involved in its conversion? What is it converted to? Once in this form, what does it do?

A

UV light converts 7-dehydrocholesterol to cholecalciferol in skin. Cholecalciferol travels to kidneys/liver via bloodstream and is converted/activated to calcitriol (Vitamin D3).

Increases blood Ca by increasing Gl absorption, increasing bone resorption (release of Ca) and limits Ca lost through kidney excretion.

17
Q

This type of burn destroys the epidermis and dermis creating edema/blisters:

A

2nd degree burn

18
Q

Which form of skin cancer affects the stratum basale? Which cells are affected in melanoma? Which is more fatal and why?

A

•Stratum basale- Basal cell carcinoma
•Melanocytes affected by melanoma
•Melanoma is more fatal - higher probability of metastasis

19
Q

Describe wound healing affecting the dermis and epidermis.

A

Epidermis - stratum basale will undergo mitosis to fill in and then up.

Dermis - if blood vessels are damaged, must clot and repair, damaged dense irregular connective is repaired by increased fibroblast secretion of collagen proteins