Exam 2: Ch. 11 Flashcards

0
Q

What are 4 examples of endocrine organs

A

Small intestines
Kidneys
Liver
Skin

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1
Q

What are 3 facts about endocrine glands?

A

No ducts
Secrete hormones
Achieve response in target organs

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2
Q

What are the 4 chemical classifications of hormones?

A

Amines
Polypeptides
Glycoproteins
Steroids (derived from cholesterol)

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3
Q

Polar hormones means that they are ____ and (can/cannot) pass through the plasma membrane
Ex: insulin

A

Water soluble….. Cannot

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4
Q

Non polar hormones are ______ which means they (can/cannot) pass through the plasma membrane
Ex: steriods

A

Insoluble in water…. Easily pass through plasma membrane

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5
Q

What are prohormones? What are prehormones?

A

Prohormone: Precursor to an active hormone
Prehormone: prwcurson to a prohormone

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6
Q

3 pattens that regulate rate of hormone secretion?

A
  • changing levels in non-hormone substances
  • neural stimulation of endocrine gland
  • control of 1 gland by another
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7
Q

What does half-life of a hormone mean?

A

Half life= time to reduce plasma concentration by 50%

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8
Q

3 ways things are removed from the blood?

A

Excretion
Metabolism
Conjugation by the liver

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9
Q

Physiological doses are within ____ ranges and produce the _____ effect

A

Normal….target

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10
Q

Pharmacological doses are within_____ ranges and produce_____ effects

A

Higher….abnormal

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11
Q

What is the priming effect called and what does it do (2 things)?

A

Up regulation….allows greater response for second hormone and increases number of receptors proteins on target cell

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12
Q

What causes desensitization?

A

Prolonged exposer to high concentrations of hormones causing a decrease in actions of the hormone

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13
Q

What is the scientific name for the pituitary gland?

A

Hypophysis

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14
Q

What is the anterior pituitary responsible for releasing? (6)

A

GH (growth hormone)
TSH ( thyroid stimulating hormone)
ACTH - stimulates adrenal cortex to secrete cortisol
FSH-(follicle stimulating hormone) GONADOTROPIN
LH- (luteinizing hormone) ovulation GONADOTROPIN
PRL- (prolactin) milk production

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15
Q

What hormones are stored (by the hypothalamus) then ultimately released by the posterior pituitary? (2)

A

ADH (vasopressin)

Oxytocin- “feel good hormone”

16
Q

What are the 2 parts of the adrenal glands?

A

Adrenal cortex

Adrenal medulla

17
Q

What does the adrenal cortex release? And what are 3 examples of these?

A

Corticoids

  1. Mineralcoricoids (aldosterone)
  2. Glucocorticoids ( cortisol)
  3. Androgens (sex steroids)
18
Q

What does the adrenal medulla release? (2)

A

Epinephrine and norepinephrine

19
Q

What are the 3 stages of stress (general adaptation syndrome)?

A

Alarm reaction
Stage of resistance
Exhaustion

20
Q

What are the 2 groups of hormones released by the thyroid glands?

A
  1. Thyroid follicles (t3/ t4)

2. Calcitonin- antagonist to PTH by lowing blood Calcium

21
Q

What does the parathyroid glands release? What does it do?

A

PTH which raises blood Calcium

22
Q

The pancreas is both _____ and ______ in function. Two cell types and what they secrete

A

Endocrine and exocrine
Alpha- secrete glucagon when blood sugars drops
Beta- secretes insulin when blood sugar raises

23
Q

What does the pineal gland release?

A

Melatonin

24
Q

What does the thymus stimulate?

A

T cells

25
Q

What are prostaglandins?

A

Most diverse group of autocrine regulators that induce an inflammatory response