Exam 2- cardio & acid base Flashcards
acids
release hydrogen ions when dissolved in water
increase H+ lower pH- more acidic
Bases
Bind with free hydrogen ions when in water
less H+ higher pH- more alkaline
Buffers
when dissolved in water can act as acids of bases depending on the pH of the body
What pH levels can result in death
pH of 7 or less and 7.8 or more
1st line of defense for acid-base regulation
chemical
buffer system
takes seconds
2nd line of defense acid-base regulation
respiratory
hypo/hyperventilation
changes pH with 02
takes minutes
3rd line of defense acid-base balance
renal
kidneys/urine
changes pH with bicarbonate
takes 24-48 hours
Arterial blood gas (ABGs)
collected in the arteries
Allen’s test
Allen’s test
checks blood flow in the hands
pH
7.35-7.45
PaCO2
45-35
HCO3
21-28
PaO2
80-100
not needed to calculate acid balance but is included in ABGs
Metabolic acidosis
low pH low HCO3
metabolic alkalosis
high pH high HCO3
respiratory acidosis
low pH high PaCO2
respiratory alkalosis
high pH low PaCO2
Causes of acidosis
starvation fever hypoxia ingesting alcohols kidney failure liver failure dehydration Respiratory- airway obstruction, COPD, asthma
Causes of alkalosis
oral antacids too much sodium bicarbonate TPN vomiting NG suctioning respiratory- hyperventilating, mechanical ventilation, high altitudes
myocardium
the heart muscle
each beat of the heart pumps?
60 mL of blood or 5L/min
what are the 4 chambers of the heart?
right atrium, left atrium, right ventricle, left ventricle
what are the two types of valves in the heart?
Atrioventricular (AV) valves and semilunar valves
what are the two AV valves in the heart?
tricuspid, mitral
What are the two semilunar valves in the heart?
aortic, pulmonic
Where is the tricuspid valve in the heart?
between RA and RV
Where is the mitral valve?
between LA & LV
What is the job of the AV valves?
act as funnels and help move blood from atrium to ventricle during diastole
during systole close to prevent backflow of blood into atrium
Where is the pulmonic valve?
separates RV and pulmonary artery
Where is aortic valve?
separates LV and aorta
What is the job of semilunar valves?
prevent backflow into ventricles during diastole
Superior and inferior vena cava?
bring deoxygenated blood from the body to RA
From the RA blood..
goes through tricuspid valve and to RV
then RV…
closes tricuspid, opens pulmonic, and propels blood into pulmonary artery
Pulmonary artery…
takes blood to the lungs
The lungs…
reoxygenate the blood
Pulmonary vein…
brings oxygenated blood to LA
blood in the LA…
goes through mitral valves and to LV
LV…
closes mitral valve, opens aortic valve, and propels blood into aorta and to the body
Mean arterial pressure (MAP)
must be at least 60 mm Hg
Cardiac output
the amount of blood pumped from left ventricle each minute
Formula for finding cardiac output
cardiac output= heart rate X stroke volume
Cardiac output ranges from?
3-6 L/min
Cardiac index
determined by dividing CO by body surface area
normal range 2.8-4.2 l/min/m2
Heart rate
the number of times ventricles contract per minute
Normal resting heart rate
60-100 beats/min
Stroke volume
amount of blood ejected by left ventricle during each contraction
Preload
degree of myocardial fiber stretch at end of diastole and before contraction
Afterload
the pressure or resistance ventricles must overcome to eject blood through semilunar valves and into peripheral blood vessels
Myocardial contractility
ability of the heart to contract
cardiac muscle strength
What effects myocardial contractility?
acidosis and hypoxia
Blood pressure
force of blood exerted on vessel walls
What three mechanisms mediate and regulate BP?
autonomic nervous system, kidneys, endocrine system
Systolic BP
amount of pressure or force generated by LV to distribute blood into the aorta with each contraction
Diastolic BP
amount of pressure or force against arterial walls during the relaxation phase of the heart
Baroreceptors and BP
are stimulated when arterial walls are stretched by increase in BP resulting in a decrease in BP
Chemoreceptors and BP
sensitive to hypoxemia
When stimulated they activate vasoconstriction and increase BP
Stretch receptors and BP
sensitive to volume or pressure changes
When hypovolemic they sense the decrease in volume and stimulate sympathetic nervous system to increase HR and vasoconstrict; increasing BP