Exam 2: Abnormal Uterine Bleeding Flashcards
Normal menstrual bleed lasts how long? Range?
5d. 2-7 day range.
Normal menstrual bleed volume loss?
40mL per cycle
Menorrhagia volume blood loss?
> 80mL
Menorrhagia frequently produces?
Anemia
Metrorrhagia definition?
Bleeding between periods
Polymenorrhea definition?
Bleeding more often than 21 days
Oligomenorrhea definition?
Bleeding less frequently than 35 days
AUB Etiology mneumonic?
PALM-COEIN
Polyps Adenomyosis Leimyoma Malignancy - Coagulopathy Ovulatory dysfunction Endometrial Iatrogenic Not yet classified
Which test has the primary role to determine if carcinoma or premalignant lesion is present?
Endometrial sampling
2 group which get Endometrial Sampling
- ≥45 w/AUB
2. Youger patients with hx of unoposed estrogen exposure or failed med management
Is neonatal vaginal bleeding normal?
Yes
Etiology neonatal vaginal bleeding?
Withdrawl from hormones while in womb
How long does the menstrual cycle vary after menarche?
for first 5-7 years
Why does menstrual cycle vary after menarche for first 5-7 years?
HPO-axis immature resulting in many anovulatory cycles
Mild anovulatory uterine bleeding lasts for how long? Flow?
Longer than normal menses >7 days or shortened cycles <24d, for at least 2 months. SLightly or moderately increased flow.
Moderate anovulatory uterine bleeding lasts for how long? Flow? Hgb?
Prlonged >7d or frequent menses q1-3 weeks. Moderate to heavy flow. Hgb ≥10.
Severe anovulatory uterine bleeding lasts for how long? Flow? Hgb?
Disruptive menstrual cycles with heavy bleeding. Hgb <10. +/- hemodynamically unstable.
Tx for Adolescent Anovulatory Uterine Bleeding?
Mestrual calendar, observe and reassure vs progestin hormone tx, f/u in 3-6 months
Tx for heavy adult AUB?
COC
Tx for intractable adult AUB?
GnRH-agonist to cease mestruation
Tx for hospitalized adult AUB?
IV conjugated estrogens
Endometrial Polyp can occur when?
At any time of reproductive or post-menopausal years
Endometrial Polyp most common in…?
Menstrual transition and early post-menopause
MC sx of Endometrial Polyp?
Intermenstrual bleeding, often after straining or heavy lifting
Dx of Endometrial Polyp?
Histologic
Tx for sympomatic Endometrial Polyp?
Polyepctomy
All women with unexplained uterine bleed should be evalued for what?
Endometrial carcinoma
When does Post-menopausal bleed occur?
≥6 months following menstrual function
How to measure endometrial thickness?
Transvaginal U/S
Endometrial thickness <4mm is a low likelihood of what?
Hyperplasia or endometrial carcinoma
Endometrial thickness >4mm which is global requires what dx?
Biopsy
Endometrial thickness >4mm which is focal requires what dx?
Sample
Tx for post-menopausal bleed
Cyclic or continuous progrestin therapy
AUB in women 19-39 most often to do what?
Pregnancy, Structural lesions, Anovulatory cycles, Use of hormonal contraception, Endometrial hyperplasia
What should always be r/o as a cause in reproductive age women - premenopausal patients with AUB
PREGNANCY