Exam 2 Flashcards
Acute Phase Response
Acute-phase proteins are a class of proteins whose plasma concentrations increase or decrease in response to inflammation. These proteins can regulate inflammation. Can cause fever.
Activated microglia:
Microglia are the immune mechanism in the brain. When activated they release destructive molecules and act as phagocytes. These phagocytes will destroy and consume a damaged or diseased neuron.
Adrenal cortex:
An endocrine organ that is responsible for secreting cortisol and aldosterone. Causes the stress response (fight or flight).
Adrenal medulla:
An endocrine organ responsible for secreting epinephrine and norepinephrine. These contribute to stress.
Adrenocorticotrophic hormone (ACTH):
Released from the anterior pituitary when CRH attaches to receptors. ACTH targets the adrenal cortex which then releases corticosteroids.
_______An extremely dynamic organ that effects growth (of bones especially), thyroid regulation, adrenal cortex regulation, mammary gland activation, and sex specific hormones.
Anterior pituitary:
________A cell that is releases its own activator. Opposed to endocrine which is activated by farway hormones.
Autocrine cell:
Nervous functions that occur without thought or effort. Controlled by brain stem. Both input and output.
Autonomic nervous system:
Corticotropin-releasing hormone (CRF)=CRH:
The same thing as CRH. It stimulates the anterior pituitary to release ACTH which targets the adrenal cortex to release corticosteroids.
_____Part of the adaptive immune system. They are found in blood and tissue and act as messenger substances. Produced by a broad range of cells (like B, T, and most cells). Often they promote or inhibit inflammation.
Cytokines:
_______Includes salivary, sweat, and mammary glands secrete the products they create and carry them to adjacent target organs or the external environment. Endocrine is more long range.
Exocrine:
Coordinated physiologic processes which maintain steady states in organisms.
Homeostasis
_________ A response to injury that generally causes vasoconstriction to promote platelet clot formation.
Inflammatory response:
T Lymphocytes
B and T lymphocytes are part of the adaptive immune system. T lymphocytes recognize infected cells and destroy those cells. They have receptors for learned pathogens. If these receptors are activated by the pathogen, that T cell will multiply quickly. Mature in thymus.
B Lymphocytes:
Matures in bone marrow. They hold antibodies in their membrane. Helper t cells will bind to B cells to release those antibodies.
Macrophage:
Phagocytes found in tissue. Can also be attached in mobile form to white blood cells that carry the large phagocyte to pathogens.
______: Mediate inflammatory and allergic responses. Famous for anaphalaxys
Mast cells