Exam 2 Flashcards
Optimal muscle functioning is dependent on: [2 items]
- Physical Activity Level
- Nutritional Status
Consequences of Sarcopenia- age related loss of skeletal muscle mass:
- Decreased Strength
- Decreased Aerobic capacity
- Decreased Functional capacity
- Decreased Bone density
Muscle impairments + Increased fat mass =
- ↑Risk of falling
- Frailty
- Comorbid conditions (IDDM)
- ↓ Protein reserves/protein synthesis
Percentage of decrease of lean muscle mass and total number of muscle fibers with aging
- ↓ 25%
Weight training + multi-nutritional supplementation can impact/lead to:
- Increased strength Type II fibers > Type I fibers
- Musculoskeletal remodeling and increases in muscle area
- Decrease / Prevent Sarcopenia
With reference to metabolic function in aging:
- After the 2nd decade, whole body resting metabolic rate declines at 1-2% per decade
- Increase in amount of fat in muscle tissue
5 changes with reference to endocrine function in aging:
- Increased insulin resistance
- Decreased growth hormone
- Decreased estrogen and progesterone
- Vitamin D deficiency
- Increased parathyroid hormone (PTH)
Effects of nutritional intake:
- May help to minimize loss of lean muscle tissue and muscle strength in older adults
- Stimulation of muscle hypertrophy through resistance exercise requires positive energy balance and positive protein intake (MPS-muscle protein synthesis)
- Moderate protein intake: 4oz of lean meat at any one meal
- Protein supplementation immediately before or immediately after resistance training session more beneficial
Nutritional intake recommendations and effects for Calcium:
…and impacts improves 4 things…
- Calcium: 1200mg/dl
- Impacts/improves:
- Blood clotting
- Bone and tooth formation
- muscle contraction
- nerve transmission
- Impacts/improves:
Nutritional intake recommendations and effects for Vitamin B12:
- 2.4μg/d
- Impacts/improves
- Nucleic acid metabolism
- Megaloblastic anemia prevention
- Impacts/improves
Nutritional intake recommendations and effects for Vitamin D:
- 200-70 400IU/d; >70 600IU/d
- Impacts/Improves
- Serum calcium and phosphorous concentrations
- Calcium absorption
- Impacts/Improves
Changes to connective tissue with aging:
- Increased stiffness
- Decreased Water Content
- Decreased strength
- Decreased cross sectional area and volume
Clinical implications of changes to connective tissue changes in aging:
- Increased risk of injury
- Pain
- Decreased function
- Disability
Joint range of motion changes in aging
- Joint range of motion (ROM) decreases with increasing age, although nonuniformly among joints, and is often direction-specific within a given joint.
- Generally, active and passive motion both decrease, with active ROM tending to decline more than passive.
Characteristics of the aging joint:
- Decreased joint space
- Increased laxity
- Altered dispersion of loads
- Altered joint movements of force
- DECREASED RANGE OF MOTION
Changes to the C-Spine with aging:
- gradual decline in ROM is seen beyond the age of 30
- extension and lateral flexion demonstrating the greatest decline.
Changes to the aging thoracic and lumbar spine:
- Examinations of thoracic and lumbar motion reveal:
- extension to be most limited in older adults
- minimal or no age-dependent decline in rotation.
Aging in the lower extremity:
- Declines in joint motion occur at the hip and foot/ankle joint complexes
- knee motion, in the absence of pathology, remains relatively consistent across the life span.
- Hip/ foot / ankle limitations most common in sagittal plane
Aging in the hip:
- Hip flexion is typically well maintained as people age.
- However, extension ROM has been shown to decrease by more than 20%.
- reduced hip extension seen with aging may directly relate to decreased walking speed in older adults
The aging ankle:
- Decreased ankle sagittal plane motion is seen with aging, particularly in the direction of dorsiflexion
The aging shoulder:
- The shoulder complex is most influenced UE joint, with flexion and external rotation being the primary motions affected.
- Compared to the lower extremity and trunk, there is relatively less influence of age on upper extremity joint ROM.
Impacts of aging on chondroid structures:
-
Excessive loading/torsion= OA
- Limited Capacity for healing
-
↑ Calcification of articular cartilage
- has been shown to occur independent of osteoarthritic changes, indicating that it is a typical response to aging.
-
Leads to ↓ tissue hydration
- Calcification, along with cellular and molecular changes associated with traumatic articular cartilage healing (lesion repair to the original hyaline cartilage with production of matrix molecules or fibrocartilage), leads to decreased osmotic pressure in articular cartilage.
- Decreased hydration compromises the viscoelastic properties and load-absorbing capacity of the cartilage
Impact of aging on IV discs (chondroid structure):
- The nucleus becomes more fibrous and less gel-like
- The annulus becomes less organized
- As a result, delineation of annulus and nucleus is diminished in older adults.
- Decreased water content is also noted in the intervertebral discs and is associated with shorter disc heights.
- The loss of disc height can lead to the chronic pathological condition referred to as spinal stenosis
- Change of the intervertebral disc also alters surrounding structures.
- The diarthrodial facet joints may experience greater loads
- elasticity of the ligamentum flavum may decrease because of decreasing tensile forces over time.
Changes to fibrous joint structures in aging:
- Increased stiffness
- Reduced elasticity.
- Decreased cross-sectional area and tensile strength.
- evidence from animal models
Changes to bony joint structures in aging:
- Directly
- changes in bone can influence the joint surfaces to alter joint mechanics
- Indirectly
- fractures and other bony structural change can alter joint alignment and function with possible secondary influences on joint mobility.
- Thickness and density of subchondral bone tends to decrease with advancing age
- this is not uniform at all joint surfaces
After the third decade formation vs. resorption in bone:
Favors resorption
Rate of bone loss in aging is affected by [4 factors]:
- Hormones
- Nutrition
- Calcium, Vitamin D
- Diseases:
- Crohn’s disease, Celiac disease, Anorexia; Rheumatoid Arthritis
- Lifestyle factors:
- Smoking, Alcohol excess, Inactivity
Hormones that affect rate of bone loss:
- Parathyroid
- Estrogen
- Testosterone,
- Progesterone
- Growth hormone
- Glucocorticoids
Bone loss in menopausal women:
- 20%-30% Cancellous bone
- 5-10% Cortical bone
- Continues for 4-8 years
• Bone loss in Post Menopausal Women and Men
- 20-25% overall
Clinical indicators of frailty [5 possible] criteria:
- must have 3 or more indicators for diagnosis
- Weakness in grip strength
- Slow walking speed
- Low physical activity
- Unintentional weight loss (>10lbs/yr)
- Self reported exhaustion
Frailty predicts:
- (Frailty increases with age)
- (Greater in women than in men)
- Worsening Mobility/ADL’s
- Disability
- Incident Falls
- Hospitalization
- Death
Second most common musculoskeletal disease
among adults:
- Arthritis
- Most common cause of disability associated with
- Activity limitation
- Reduced QOL
- High Health Care costs
- Impacts Women>Men
- Most common cause of disability associated with
Non-Modifiable Risk Factors for arthritis:
- Increasing age
- Gender
- Genetics
- Rheumatoid arthritis
- Systemic lupus erythematosus
- Ankylosing spondylitis
Modifiable Risk Factors for arthritis:
- Overweight/ Obese
- Joint injuries
- Certain infections
- Occupations
- Reduced Proprioception
- Poor joint biomechanics
- Muscle weakness
- Inactivity
Characteristics of Osteoarthritis
- Degenerative joint disease
- Most common form of arthritis
- Characterized by
- Focal and progressive loss of the hyaline cartilage of joints
- Bony changes
- Decreased ROM/Function
- Pain/Swelling
Osteoarthritis interventions include:
- Exercise-strengthening, aerobic, water-based
- NSAIDS and pharmacological interventions
- Lifestyle education
- Increased activity
- Activity pacing
- Weight reduction
- Bracing-Valgus/Varus
- Footwear assessment
Rheumatoid Arthritis is/causes:
- Chronic, Inflammation of synovium of joints
- Joint Damage
- Pain
- Loss of function
- disability
Three Phases of RA:
-
Phase one:
- Swelling of synovium-pain, warmth, stiffness, erythema, joint effusion
-
Phase two:
- Thickening of the Synovium
-
Phase three:
- Release of enzymes from inflamed cells
- Bone and Cartilage destruction
- Joint malalignment, pain, ↓ ROM
- Release of enzymes from inflamed cells
Interventions for RA:
- High-Intensity strength training and aerobic activity
- Less joint damage
- Less progression of joint damage
- Improved muscle strength
- Must adjust intensity according to current symptoms and functional abilities
Osteoporotic fractures lead to:
- Loss of height
- Increased Thoracic kyphosis that worsens over time
- Breathing difficulties, abdominal pain, digestive issues
- Decreased QOL, Mobility, Energy
- Pain and deterioration of physical function
Complications of Hyperkyphosis as a result of osteoporotic fractures:
- Reduced muscle strength
- Increased mediolateral body sway
- Decreased balance with gait
- Increased risk of falls
According to Mentz et. al., programs to improve mobility and decrease the risk of falls:
- focused on improving strength and flexibility of the foot and ankle
- attempt to enhance plantar sensation
According to Mentz et. al….independent predictors of balance and function:
- Ankle flexibility
- Plantar tactile sensitivity
- Toe plantar strength