Exam 2 Flashcards
How did we figure out the localization of language?
Lesion studies, stimulation studies and imaging studies.
What happens when you present an object to the right hemisphere by touching it with left hand or presenting in the left visual field?
- Patient can pick out the correct object with left hand, but cannot with right hand
- Patient claims nothing was presented
What happens during neural maturation?
Dendrites and axons develop.
What is the Kennard Principle?
That functions are spared when injury happens during infancy–before 1.
What is alternating attention?
Ability to shift focus and move between tasks with different cognitive requirements.
What conditions are caused by incorrect pathway formation?
Athetosis and dystonia.
Complete this graph of the cognitive-emotional interaction theory.
Name the three types of inattention.
Inattentional blindness
Change blindness
Attentional blink
What is a neural tube?
A rolled-up sheet of cells that will form the brain and spinal cord. It is formed 3 weeks after conception.
What abnormal development is this?
Polymicrogyria
What behavioral changes happened in monkeys after frontal lesions?
- Reduced social interaction
- Loss of social dominance
- Inappropriate social interaction
- Altered social preferences
- Reduced affect
- Reduced vocalization
What happens when you show a word in the left visual field of a split brain patient?
They do not report seeing the word but can draw the word–right hemisphere.
List the embryonic development of the cortical gyri in order.
- Gyrus rector, insula, cingulate
- Parahippocampal, superior temporal
- Prerolandic and postrolandic, middle temporal, superior and middle frontal, occipital
- Inferior and transverse temporal, medial and lateral orbital, angular, supramarginal
- Paracentral
- Anterior and posterior orbital
Which hemisphere is dominant for facial recognition?
The right.
Identify the word processing areas.
Describe the Wernicke-Geschwind model.
A model that explains the relationship between Broca’s and Wernicke’s areas.
Begins at the angular gyrus (posterior temporal lobe). Information flows towards Broca’s area through
- Wernicke’s area (spoken word comprehension, sound images of words)
- Arcuate fasciculus (connects W with B)
- Broca’s area (motor programs for speaking words)
Complete Posner’s Attention Model
What kind of amnesia is linked to damage to anterior thalamic nuclei?
Anterograde amnesia.
What is the difference between short-term and working memory?
The short-term memory is a temporary storage of information, whereas the working memory allows for temporarily storing and manipulating information.
Describe the role of the cerebellum in memory.
Classical conditioning.
Describe the Papez theory of emotion.
Limbic structures (thalamus, hypothalamus, mammilary bodies, cingulate gyrus and hippocampus) act on the hypothalamus to produce emotional states.
What are the four components of emotion?
- Physiology
- Distinctive motor behaviour
- Self-reported cognition
- Unconscious behaviour
In which hemisphere is the speech if a dichotic listening subject reports hearing in the right ear?
Left hemisphere.
What is Kluver-Bucy syndrome?
It results from bilateral damage to to amygdala and inferior temporal cortex.
Symptoms include:
- Tameness and loss of fear
- Indiscriminate dietary behaviour (will eat anything)
- Indiscriminate sexual activity
- Hypermetamorphosis: irresistible impulse to notice and react to everything in sight
- Examine objects by mouth
- Visual agnosia
Describe the role of the temporal cortex in memory.
The anterior temporal cortex has a role in semantic memory.
What are the stages of brain development?
- Cell birth (neurogenesis, gliogenesis)
- Cell migration
- Cell differentiation
- Cell maturation
- Synaptogenesis
- Cell death and synaptic pruning
- Myelogenesis
What problems can lead to brain deformities?
Genetics, trauma and toxic agents.
Define attentional blink.
Failure to detect a second stimuli if presented within 500ms of the first.
Describe the cognitive-emotional interaction theory of emotions.
Proposed by LeDoux. The emotional system evalutes internal and external stimuli. Circuits in the amygdala interact with several cortical areas to influence affective behaviour.
Describe the role of the amygdala in memory.
Emotional conditioning, storing emotional events and coding emotional signals.
Damage disrupts emotional memory, but not implicity or explicit memory.
What guides synapse formation?
Genes, cues, and signals.
What is the role of the anterior cingulate gyrus in emotion?
Emotional monitoring and evaluation.
Name and describe the cortical components of language.
- Broca’s area: working memory, articulation
- Insula: lesion leads to speech apraxia
- Wernicke’s area: holding sentences in memory, rhyming
- Posterior middle temporal gyrus: lesion leads to fluent aphasia
- Superior temporal gyrus: sentence comprehension
- Arcuate fasciculus: recurring utterances
Name the models of memory.
Sensory modality-based
Content-based
Time-based
Storage capacity-based
What is sustained attention?
Ability to maintain attention and remain alert to stimuli over prolonged periods of time.
What is anterograde amnesia?
Inability to acquire new memories.
What is the purpose of the highlighted areas?
What is the Wada technique?
Putting one hemisphere to sleep with barbiturate sodium amytal, and checking function during that time.
Describe the asymmetry in emotional processing in the frontal lobe.
- Left hemisphere lesions: flattened mood
- Anterior lesions: reduction in facial expression
- Left frontal leasions: decrease in talking
Who was Leborgne?
Broca’s first case. He was also know as Tan–the only word he could say. Had a lesion in Broca’s area.
Which brain structures support the alert function?
Locus coerulus
Right frontal cortex
Parietal cortex
Define change blindness.
Failure to detect changes in the presence, identity or location of objects in scenes.
Describe Korsakoff’s Syndrome.
Characterized by:
- Anterograde and retrograde amnesia
- Confabulation
- Meager conversation content
- Lack of insight
- Apathy
Caused by thiamine (B1) deficiency.
Damage may be in medial thalamus, mammillary bodies, or caused by general atrophy due to alcoholism.
What effects did Wilder Penfield produce with electrical stimulation?
- Total arrest of speech
- Hesitation and slurring
- Speech distortion and repetition
- Number confusion
- Naming difficulties
- Misnaming and perseveration
Name and describe the three pure aphasias.
- Alexia without agraphia: Poor reading. Lesion located in left lateral occipital sulcus (visual word form area).
- Agraphia: Poor writing. Lesion located in left parietal region (supramarginal gyrus or insula).
- Word deafness: Poor comprehension and repetition. Lesion located in tracts between auditory systems and Wernicke’s area.
What happens when you present a word in the right visual field of a split-brain patient?
He can read or name the word–left hemisphere dominant speech.