exam #2 Flashcards
agonist
ENHANCE the activity of a neurotransmitter
≠ EPSP
antagonist
REDUCE the activity of a neurotransmitter
≠ IPSP
how does Botox work at the synapse?
it’s an antagonist. decreased ACh at the neuromuscular junction
how does cocaine work at the synapse?
it’s an agonist. it keeps DA in the synapse longer
Metabolic tolerance
changes in metabolic enzymes
example of metabolic tolerance?
ALDH levels are increased in chronic drinkers
Cellular tolerance
changes in brain cells
example of cellular tolerance?
decreased receptor density
learned tolerance
changes in behavior
examples of learned tolerance?
alcohol use and beam walking in rats, heroine users and overdosing
what neurotransmitter system is involved with addiction?
mesolimbic dopamine system
Anterior (rostral) direction
toward the head
Posterior (caudal) direction
toward the tail
ventral direction
toward the belly
dorsal direction
toward the back
ipsilateral
structures on the same side of the midline
contralateral
structures on opposite sides of the midline
Meninges
3 protective membranes that surround the brain and spinal cord
Dura mater
tough outermost layer (meninge)
pia mater
delicate innermost layer (meninge)
Arachnoid membrane
lies between dura mater and pia mater (meninge)
2 division of the automatic nervous system?
sympathetic nervous system and parasympathetic nervous system
sympathetic nervous system
arouses the body for action, “fight or flight” response
parasympathetic nervous system
“rest and digest” response, opposes the sympathetic response
what kind of information travels along the dorsal portions of the spinal chord?
sensory info (body to the brain)
what kind of information travels along the ventral portions of the spinal chord?
motor info (brain to body)
what are the 3 divisions of the hindbrain?
medulla, cerebellum, pons
medulla
oldest part of the brain, control vital functions (like heart rate and breathing), contains several nuclei
cerebellum
“little brains”, contains the most neurons, involved in movement/balance
pons
bridge….connects cerebellum to the rest of the brain, contains several nuclei
tectum
located in the midbrain…the roof
superior colliculi
visual part of the tectum….. ex: friend waving across the street