Exam 2 (5-8) Flashcards
Risk Factors in Pregnancy
- age
- parity
- lifestyle
- low income
- existing health conditions
- genetics
- environment
Age and Pregnancy Risk Factors
- being too young or old
- young: high BP, anemia, go into labor earlier, STI’s, decreased prenatal care
- old (over 35): higher risk for C-sections, delivery complications, prolonged labor, infants with genetic disorders
Parity and Pregnancy Risk Factors
- 5 or more pregnancies
- risk for preterm labor
Lifestyle and Pregnancy Risk Factors
- poor nutrition, vegetarian diet
- substance use: alcohol or drugs
Low Income and Pregnancy Risk Factors
- no prenatal or inadequate care
- screen for drugs
Existing Health Conditions and Pregnancy Risk Factors
- diabetes
- PCOS
- obesity
- zika
- autoimmune diseases: lupus, multiple sclerosis
- cardiac disease
- HIV/AIDS
Genetics and Pregnancy Risk Factors
- defective -> chromosomal abnormalities could lead to spontaneous abortion
Pregestational Pregnancies at Risk
- substance abuse
- diabetes
- anemia
- HIV/AIDS
- heart disease
Gestational Onset Pregnancies at Risk
- hypertensive disorders
- spontaneous abortions
- ectopic pregnancies
- Rh alloimmunization
- herpes
- GBS+
- CMV (herpes)
- hyperemesis gravidarum
- gestational trophoblatic disease (multiple tumors)
Substance Abuse During Pregnancy
- 30% of women
- rates higher in 1st and 2nd trimester
- universal screening for everyone
- may be associated with decreased fetal growth restriction, stillbirth, preterm birth, neurological development: hyperactivity, poor cognitive function
- increased use of medically assisted treatment
- most at risk: below poverty level, exposed to violence, DV, depression, less than high school education, unmarried, unemployed
- most common: smoking cannabis in white women
- frequently misdiagnosed
- autonomy vs nurse’s obligation
- fear of losing custody: decrease prenatal care
- prenatal use: withdrawl syndrome in newborn
Heroin Treatment
behavioral therapy mized with pharmacological therapy (MAT) medical assisted therapy
* methadone
* buprenorphine
* naltrexone
Methadone: Heroin Treatment
- most common
- during pregnancy, brings addicted woman into agencies that promote prenatal care
- help with withdrawl symptoms
Buprenorphine: Heroin Treatment
- better treatment adherence with fewer side effects and overdoses in comparison to methadone
Naltrexone: Heroin Treatment
- opioid antagonist, non-addictive, may improve compliance if an issue
- work through same opioid receptior, but safer
Patho of Diabetes
diabetes: metabolic disease with hyperglycemia from insulin secretion defects
* makes blood more viscous and causes high BV, cellular dehydration, polyuria, and polydipsia (excessive thirst)
* starts to burn both proteins and fats = ketones and fatty acids which causes weight loss because of breakdown in tissue
* change in vascular circulation with organs
Four Cardinal S/S of Diabetes
- Polyuria
- Polydypsia
- Weight Loss
- Polyphagia
Polyuria in Diabetes
excrete large volumes of urine
* glucose hyperconcentrated = kidney loses ability to pull glucose from water
* osmotic pressure rises, H2O cannot be absorbed back into blood = urination
Polydipsia in Diabetes
dehydration in cells, can be from polyuria
Weight Loss in Diabetes
breakdown of fats and muscles to make ketones and fatty acids
Polyphagia in Diabetes
tissue breakdown = starvation
person may eat excessive amounts of food
Classifications of Diabetes Mellitus
- Type 1 DM: absolute insulin deficiency
- Type 2DM: insulin resistance
- Gestational Diabetes: any degree of glucose intolerance
White’s Classification of Diabetes
in pregnancy
based on age of diabetes, duration of illness, presence of any organ involved
* eyes and kidneys
* classes A-C: positive pregnancy outcome if glucose controlled
* classes D-T: poor outcome, vascular damage
Influence of Pregnancy of Diabetes on Physiological Changes in 1st Tri.
alter insulin requirements
* insulin decreases because increased estrogen and progesterone stimulates pancreas to make more insulin
* this increases peripheral use of glucose
* hypoglycemia with N/V
Influence of Pregnancy of Diabetes on Physiological Changes in 2nd and 3rd Tri.
maternal metabolism directed toward supplying adequate nutrition for fetus
* placental hormones: cause insulin resistance
* promote more blood glucose to transfer through placenta
* fetus produces nore glucose when it gets glucose
Influence of Pregnancy of Diabetes on Hormones
- hPL
- somatotropin (growth hormone)
- promotes more insulin on bloodstream
- do not produce sufficient amount of insulin to maintain glucose homeostasis
Other Influences of Pregnancy in Diabetes
- accelerates progress of vascular disease
- more difficult to control in pregnancy
- fetus will get bigger since insulin turns into fat
Maternal Risks with Diabetes
- poor glycemic control = miscarriage and big baby (over 4000g)
- risk for C-section
- hydramnios: fetal urination, uterine dysfunction, infection
- hyperglycemia and ketoacidosis
- high risk for infections
- worsening retinopathy
Fetal Neonatal Risks with Diabetes
produce insulin around 14 wks = growth hormone
* macrosomia: could have birth injury delivering vaginally
* congenital abnormalities
* IUGR: interuterine growth retardation = decreased profusion to placenta with decreased vascularity
* respiratory distress syndrome: inhibit enzymes necessary for surfactant production
Clinical Therapy for Diabetes
- early detection and diagnosis
- assess risk at 1st visit
- if low risk: screen at 24-28wks
- if high: screen asap
Diabetes Levels
> 128 mg/dL fasting glucose
200 mg/dL random glucose
6.5% ha1c
Increased Risk for Diabetes
- over 40
- family history
- obesity
- PCOS
- hypertension
- glucosuria
- prior macrosomic, malformed, stillborn
Screening for Gestational Diabetes
at 24-28wks
1hr 50g glucose tolerance test
Screening for Diabetes: Negative
lower than 140
routine care
Screening for Diabetes: Positive
over 140
3hr 100g GTT test
fasting 95
1hr: 180
2hr: 155
3hr: 140
if 2 values exceed these: positive
negaive = 1 value greater
Hemoglobin A1C Control
normal: 4-5.9%
hemoglobin will stick to RBC
* levels between 5-6 = fetal malformation rates comparable to those observed in normal pregnancy (2-3%)
* goal for HA1C = 3 months prior to conception
* HA1C concentration = fetal anomaly rate 20-25%
Pregnancy Complications
- Rh factor
- ABO incompatability
- ectopic pregnancy
- HSV
- GBS+
- preeclampsia/eclampsia
- gestational trophoblastic disease
Rh Alloimmunization
Rh = inherted protein on surface of RBC (+)
no protein (-)
Rh - Mother
Rh + baby
antibody-antigen response
sensitized mother
No Treatment to Sensitized Mother
- jaundice
- anemia
- brain damage
- heart failure
- death
Maternal Alloimmunization
when woman’s immunse system is sensitized to foreighn erythrocyte surface antigen
stimulates the production of IgG antibodies
Sensitized Woman
small amounts of fetal blood cross the placenta
maternal IgM antibodies are produced and RhoGam will not help since she is sensitized
2nd Pregnancy and Sensitized Woman
Rh+ child - IgG antibodies produced and cross placenta
risk for hemolysis of fetal RBC
Indirect Coomb’s Test
identifies antigen that could cause problems in newborns or mother
possible need for transfusion
positive test = antibodies present, no RhoGam
negative test = no antibodies present
Amniocentesis and Rh Compatability
using amniocentesis to test if fetus is Rh + or -
Ultrasound and Hemolytic Anemia
faster blood flowing through ultrasound
Other Interventions for Rh Incompatability
- monitoring pregnancy
- intrauterine transfusions of newborn
- exchange transfusion of newborn: erythopoietin and iron
Goals of Rh Incompatability
- prevent sensitization
- treat isoimmune disease in newborn
RhoGam Shot
when mom is not sensitized with - titer of + fetus
300mcg Rh immune globulin (RhoGam) IM at 28 wks
repeat dose within 72 hrs with + newborn
also given if any mixing of blood occurs
ABO Incompatibility
common and mild type of hemolytic diseases in babies
mom type O and infant type A or B
Maternal Serum Antibodies Crossing the Placenta
- can cause hemolysis of fetal RBC
- mild anemia
- hyperbilirubinemia
- not treated antepartally
Perinatal Infections
- herpes simplex virus
- GBS
HSV
1:6 between ages 14-49 are infected
Fetal Neonatal Risks with HSV
- spontaneous abortion
- preterm labor
- intrauterine growth resistance
- neonatal infection
- varies with route of birth and presence of lesions
- c-section of outbreak during labor
Clinical Therapy of HSV
- antiviral after 36wks gestation
- acyclovir, famciclovir, valacyclovir
- can reduse the need for a c-section
GBS
- in lower gastrointestinal tracts, urogenital tracts
- fetal risk: unexpected intrapartum stillbirth
- clinical therapy guidelines
Hypertensive Disorders
- chronic hypertension
- chronic hypertension with superimposed preeclampsia
- preeclampsia/ecclampsia
- gestational hypertension
Preeclampsia Diagnosis
- BP of over 140/90 with proteinuria
Preeclampsia Diagnosis: Before 20 Weeks
- no stable proteinuria and chronic hypertension
- new or increased proteins and preeclampsia superimposed on chronic hypertension
Preeclampsia Diagnosis: After 20 Weeks
- proteinuria and preeclampsia
- no proteinuria and gestational hypertension
Patho of Preeclampsia
- affects 5-10% of women
- multiorgan disease
- spiral arteries of uterus do not increase in diameter to promote perfusion to placenta
- vascular remodeling does not happen and decrease in placental perfusion and hypoxia occur
- endothelial dysfunction and vasospasm
- imbalance of vasodialating hormones: prostacyclin and vasoconstricting hormones: thromboxane
Three Characteristics of Preeclampsia
- vasospasm and decreased organ perfusion
- intravascular coagulation
- increased permeability and capilary leakage
Vasospasm and Decreased Organ Perfusion: Preeclampsia
- hypertension
- uteroplacental spasm - intrauterine growth restriction
- glomerular damage - oliguria (small amounts of urine)
- cortical brain spasms - CNS problems
- retinal arteriolar spasms - blurred vision
- hyperlipidema
- liver ischemia
Intrautuerine Coagulation: Preeclampsia
- hemolysis of RBC
- platelet adhesion - low platelet count and DIC (affects clotting)
- increased VIII antigen
Increased Permeability and Capilary Leakage: Preeclampsia
- decreased serum albumin levels and decreased intravascular volume as fluid with protein
- increase in blood viscosity
- proteinuria
- generalized edema
- pulmonary edema
Clinical Manifestations and Diagnosis
don’t use mild
proteinuria is not an official criteria
BP over 140/90 on two occassions, 4hrs apart after 20wks
low platelets, renal insufficiency, impaired liver function
Risk Factors to Preeclampsia
- first pregnancy
- materal age below 19 and above 30
- african american or hispanic
- low socioeconomic status
- family history
- chronic hypertension
- diabetes
- lupus
- multigestation
- gestational trophoblastic disease
- fetal hydrops
Nursing Assessment: Worsening Preeclampsia
- increased edema
- scotomata (vision problems)
- blurred vision
- decreased urinary output
- epigastric pain
- vomiting
- bleeding gums
- persistent/severe headache
- neurological hyperactivity: deep tendon reflex, clonus (involuntary muscle contractions)
- pulmonary edema
- cyanosis
Eclampsia
- seizures or coma
- multifocal, focal, generalized
- nursing assessment suring seizure
- treatment: magnesium sulfate, antihypertensive agents
- fetal reaction to survive: should reconsider when mom stabilizes
Preeclampsia Treatment
- early detection
- treat symptoms
- early treatment: bedrest, regular diet, monitor BP, proteinuria
- hospitalization if more severe
- therapeutic goal: diastolic BP between 90-100
- meds: hydralazine, labetol, oral nifedipine, magnesium sulfate: CNS depressant, seizure prophylaxis, smooth muscle relaxant, safe for fetus
HELLP Syndrome
continuation of preeclampsia
H) hemolysis
E) elevated
L) liver enzymes
L) low P) platelet count
* associated with severe preeclampsia
* symptoms: N/V, malaise, epigastric pain
Postpartum and HELLP
- possibility of HELLP
- eclampsia for 48hrs
- increased cardiovascular issues in future
Preeclampsia Maternial Consequences
- with eclampsia: 20% maternal mortality rate
- risk of: abrupto placenta, retinal attachment, cardiac failure, cerebral hemorrhage/stroke
Preeclampsia Fetal Consequences
- fetal growth retardation
- fetal hypoxia
- fetal death
Ectopic Pregnancy
- pregnancy outside of uterine cavity (2% of all preg)
- 95% implant in the fallopian tubes
- normal cell growth and division
- pressure from growth causes symptoms
- will rupture if pressure is too great: maternal death in 1st trimester
Risk Factors to Ectopic Pregnancies
- history of STI’s or PID
- previous tubal, pelvic, or abdominal surgery
- endometriosis
- IVF or other methods of assisted reproduction
- in utero: Diethylstilbestrol (DES) exposure with abnormalities of reproductive organs
- use of IUD
Management of Ectopic Pregnancies
- salpingostomy/salpingectomy (removal of conception product/tube)
- methotrexate
- monitor blood loss
- emotional support
Hydatiform Mole (Molar Pregnancy)
- abnormality of placenta from fertilization
- forms grape-like cysts that fill entire uterus instead of normal placental tissue
- vast proliferation of trophoblastic tissue associated with loss of preg and can lead to the development of cancer = choriocarcinoma
- 20% become malignant
2 Types of Molar Pregnancies
- complete molar preg: ovum with no functioning or missing nucleus or empty egg with normal sperm
- partial: some fetal tissue present with normal ovum but two sperm
Increase Incidence of Molar Preg
- women with low protein intake
- > 35 years old
- Asian women
- experienced prior miscarriage
- undergone ovulation stimulaiton (clomid)
S/S of Molar Preg
- rapid vaginal growth
- vaginal bleeding
- N/V
- hypertension
- abnormally high hCG levels
- no fetal heartbear
- ultrasound: only cysts and no fetus
Management of Molar Preg
- D&C
- monitor for malignancy through serial hCG levels
- no preg for 1 year
- emotional support
Complications of Labor
- bleeding disorders (PP and PA)
- placenta previa
- placental abruption
- polyhydramnios
- oligohydrammios
Placenta Previa
- implantation in lower uterine segment, over or near cervical os (the opening in the cervix at each end of the endocervical canal)
- may be multifactional uterine scarring predisposes to lower segment implantation
Risk Factors: Placenta Previa
- scarring from previos previa, prior C/S, abortion, multiparity
- large placenta, multigestation
- infertility, non-white, low SES, short interpregnancy interval
- impeded endometrial vascularistriction: >35 years old, diabetes, smoking, cocaine
- hemorrhage for mom
- prematurity, malpresentation, IUGR/fetal anemia for fetus
S/S of Placenta Previa
- painless, intermittent bleeding
- confirmed by ultrasound
- lower uterine segment not as responsive to oxytocin - use methergine
Nursing Assessment: Placenta Previa
- avoid vaginal exams
- monitor vitals and SpO2
- continuous EFM (electronic fetal monitoring)
- assess for preterm labor, non-stress test
- BPP (biophysical profile), amniocentesis for lung maturity studies
Active Bleeding in Placenta Previa
- large bore IV access
- meaure I and O
- weigh pads
- CBC, coagulation studies, T and X
- O2 at 95%
- anticipate possible c-section birth
Placental Abruption
- premature separation of a normally implanted placenta
- bleeding may be external or concealed
- severity depends on degree or separation
- types: partial or complete
Risk Factors of Placental Abruption
- hypertension
- seizures
- blunt trauma to maternal abdomen
- short umbilical cord
- previous history of abruption
- smoking or cocaine use
S/S of Placental Abruption
- sudden onset of intense, sharp abdoment pain
- uterine irritabilitym tachysystole, increased resting tone
- vaginal bleeding may or may not be present
- dark “port wine” stained amniotic fluid
- fetal heart rate patterns indicative of compromise
- maternal tachycardia
Management of Placental Abruption
- assess fundal height
- consider abdominal girth measurements
- assess for increased pain or tenderness
- assess for S/S of shick
- I and O
- weigh pads
- provide continuous EFM
- provide O2 to maintain above 95%
- anticipate and prepare for emergency delivery
- observe for DIC, administer blood products
Polyhydraminos
- excessive amniotic fluid, over 2000mL
- associated with fetal GI abnormalities and maternal diabetes
- treatment: shortness of breath and pain - amniocentesis
Oligohydramnios
- scanty amniotic fluid, less than 500mL
- etiology - unknown
- risks: detal adhesions and malformation
- treatment: amnioinfusion
Assessment Prenatally
- anticipate what may have compromised fetus in utero
- maternal and prenatal history: blood type, lab values, GBS/HIV/HepB, diabetes, preeclampsia, smoking/substance abuse, trauma and disorta wiht high glucose levels
Assessment Intrapartum
anticipate what will occur in labor
* analgesia/anesthesia, prolonged rupture of membranes, meconium stained amniotic fluid, nuchal cord, use of forceps/vacuun, evidence of fetal distress, precipitous birth
Timing/Frequency of Assessments
- 1st assessment right at 30sec
- about 85-90% do not need any assistance to life
- placed skin-to-skin
- ABC immediately at birth
- thermoregulation
- APGAR scoring
- physical exam of newborn
- considerations of newborn’s classification
Timing of Newborn Assessment
- admission assessment: 2nd assessment
- physical exam
- general measurements
- gestational age assessment
- attachment
Ongoing Assessments
- process of adaptation to extrauterine life
- nutritional status: ability to feed
- behavioral state/organizational abilities
General Measurements
- weight: avg 2500-400g, 70-75% of body is water weight
- head circumference: avg 33-35cm, 2cm greater than chest circ
- chest circ: nipple line
- abdominal circ
- length: range of 18-22in (48-52cm)
Birth Weight and Gestational Age Classes
- LGA (large)
- AGA (appropriate)
- SGA (small)
Gestational Assessment: New Ballard Scale
- neuromuscular activity
- physical maturity
- maturity rating table
Estimating GA
first 4hrs after birth
* can preduct at-risk infants and keep alert of problems
* Ballard Tool
Ballard Tool
- each finding given point value: -5 to +5
- maternal conditions may affect certain components: stress and diabetes
Physical Maturity Characteristics Assessment
- skin
- lanugo
- sole (plantar) creases
- areola and breast bud tissues
- ear/eye formation
- genitalia
Skin
7 sub-classifications from transparent skin to peeling
Lanugo
thin, soft hair usually arounf 24-25wks
Sole Creases
full term: deep sole creases down to and including heel as skin loses fluid and dries after birth
Ear Forming and Cartilage
more premature: not as thick of cartilage
Eyes
fused eyelids premature
see how tight or loose
Male Genitals
should have 5-10mL breast buds
term infant: fully descended testes and entire surface of scrotum is covered by rugae
Female Genitals
prominent clitoris, labia majora widely separated, labia minora protudes beyond labia majora
LM can be dark in some ethnic groups
Neuromuscularity in Newborn
- posture in supine position
- square window
- arm recoil
- popliteal angle
- scarf sign
- heel to ear
Preterm Resting Posture
supine, undisturbed, should be more flexed with increased tone but is more flaccid
Full Term Resting Posture
increased tone and more flexed
Square Window Sign
bending wrist
full term infant will be able to touch hand to wrist
Arm Recoil
- lying in supine: flex both elbows, hold for 5sec, extend arms at baby’s side, and release
- angle of recoil to which forearm springs back into flexion is noted
- preterm will not have any arm recoil
Popliteal Angle
- bend knee and push foot towards head
- mature: little flex and cannot bend over 90 degrees
- preterm: straight leg and lots of flex
Scarf Sign
- extend infant arm across body
- mature: bend elbow, not very flexible
- preterm: straight arm, lots of flexibility
Scarf Sign
- extend infant arm across body
- mature: bend elbow, not very flexible
- preterm: straight arm, lots of flexibility
Heel to Ear
- extend foot to ear
- mature: unable to do this
- premature: touch foot to ear
General Appearance of Newborn
head large for body
tend to stay in flexed position, can hold head up
Pulse Rates
- 110-160
- sleep can go down to 70
- crying can go up to 180
- check apical pulse for 1min
Respiratory Rates
- 30-60 resp/min
- diaphragmatic but synchronus with abdominal movement
- count for 1 full minute
BP Rates
- 70/50 and 45/30 at birth
- 90/60 at day 10
Temperature
- normal range: 97.7-99.4
- axillary: 97.7-99
- skin 96.8-97.7
- rectal 97.8-99
Anterior Fontanelle
- diamond shaped
- closes in 18mo
- palpable with 2nd and 3rd finger
Posterior Fontanelle
- triangle shaped, no buldging
- closes 8-12 wks
- depression: dehydrated or decreased intracranial pressure
- bulging: increased intracranial pressure or trauma
Molding
baby in vertex positions for vaginal delivery
* pressure on head against cervix
* flat forehead and rises to point at posterior of skull “cone head”
Cephalohematoma
- collection of blood from broken blood vessels that build up under scalp
- does not cross suture line
Craniosynostasis
- premature fusion of cranial sutures
- results in growth restriction perpendicular to affected sutures and compensatory overgrowth in unrestricted regions
- will need surgery
Plagiocephaly
- rapidly growing head attempts to expand and meets type of resistance such as flat surface like crib
- helmets used to fix aesthetically
Eyes: Physical Assessment
- tearless crying: immature lacrimal ducts
- peripheral vision: like close up objects
- can fixate on near objects
- can perceive faces, shapes, colors
- blink in response to bright light
- pupillary reflex present
Ears: Physical Assessment
- soft and plaiable
- ready recoil
- pinna parallel with inner and outer canthus
Eye and Ear Variations
- low set ears: chromosomal abnormalities or renal problems
- abnormal malformations: absent pinna, abnormal folds
- edema in eyelids from delivery or subconjunctival hemorrhage
- transient strabismus: cross-eyed