exam 2 Flashcards
what are some examples of infectious diseases?
Smallpox, Hepatitis, syphilis, influenza, measles, cholera, bubonic plague
In which ways were infectious disease eradicated in the 1960’s?
- immunization (vaccinations)
- public health measures: pasteurization of milk, proper disposal of sewage, purification of water, improvements in personal hygiene and nutrition
- antibiotics
What are the different types of infectious agents?
parasites, bacteria, viruses
give an example of a parasite, bacteria, and virus
parasite: ringworm, pin worm, roundworm
bacteria: staphylococci, tuberculosis, syphillis
virus: hepatitis, HIV, small pox, coronavirus
What are some means of transmission for infectious diseases?
- water
-food - vectorsliving organisms that transfer from one hose to another like animals
- aerosols:
-fecal to oral
The chain of infection transmission pattern in linked between what?
pathogen, reservoir, mode of transmission, and susceptible host
what are the components of the chain of infection?
- susceptible host ( babies, children, elderly, immunocompromised people, unimmunized people, anyone)
- infectious agent (parasite, virus, bacteria)
- reservoir ( food, water, soil, human, wild animals, pets)
portal exit: mouth ( saliva, vomit), cut in the skin (blood), diapering and toileting (stool)
-mode of transmission: contact (toys, hands, sand), droplets( sneeze, cough, or speak) - portal of entry: mouth, eyes, cuts in the skin
how do public health measures relate to the chain of infection?
public health measure aim to interrupt the chain of infection by targeting its most vulnerable links
How is eradication possible?
if there’s is no human reservoir and if the vaccine exists
when was small pox eradicated? is Polio eradicated everywhere/
- small pox was eradicated in 1977
polio is eradicated in the western hemisphere but is still in other countries. in these other countries there is opposition of getting vaccinations due to various reasons (lack. of trust in the government, moral/ religious beliefs, misinformation )
what are the public health measures that are aimed against infectious disease?
- contact tracing
- epidemiological surveillance
- quarantine
immunization and treatment of those who are infected
what is herd/ community immunity? what are the thresholds for herd immunity for certain diseases?
herd immunity is when a proportion of the population is immune to a disease due to being immunized or having had the disease before and protects those who are not as it lowers the chance of disease being spread from person to person
-thresholds:
- rubella 83-85%
influenza - 80-90%
- mumps - 75-86%
measles - 83-94%
polio - 75- 86%
how is herd immunity lost?
when people do not get vaccinated or people move out of the place they have lived in long enough to create the herd immunization if they are not vaccinated
what are some structural failures of the ebola outbreak?
- lack of funding in the health care systems in Guinea, Sierra Leone, and Liberia
-lack of sufficient epidemiological surveillance and contact tracing - lack of severity acknowledgement from local government and WHO
lack of resources (space for the infected to go, PPE) - traditional burial rituals that spread the disease increasingly
- cross border migration
What is HIV? when was it first recognized in the US? what was it caused by? what are the facts about HIV?
-HIV - Human Immuno Defiency Virus
- it was first recognized in the us in 1981
- it is caused by a retrovirus and attacks the immune system
- screening tests recognizes the antibodies
there are many drugs now available to treat it however there is no cure
How is HIV/ Aids transmitted?
- sexual contact
- sharing of needles:
- through intravenous drugs use, epically use of unsterile needles
- mother to infant ( vertical transmission) through:
prenatal or during birth, breastfeeding - blood transfusions: prevented through blood screenings
( circumcision helps protect men against contracting HIV from women but it does not prevent women contracting from men)
what are some examples of emerging diseases?
- ebola
- monkey pox
- west nile virus
- SARS and other corona viruses
- hantavirus
- other hemorrhagic viruses
what are some factors that lead to the emergence of new infectious disease:
- international travel
- modern agricultural practices
international distribution of food and exotic animals - increasing injection drug use and risky sexual behavior
All about infleunza
- RNA virus like HIV (genetic material of the virus is RNA not DNA)
- the virus is constantly mutating
- vaccine must be changed constantly
- new lethal strains appear periodically
- epidemic of 1918-1919 killed 20 million to 20 million worldwide
what are two types of influenza that are constant threats?
bird flu and H1N1
T o F: Both the inactivated and live attenuated (weakend) vaccine usually
made using egg-based manufacturing process
True
How many national influenza centers are there in 114 countries that conduct year round surveillance of infleunza?
144
which large international organization olds a meeting twice a year about which strain of influenza to include in a vaccine?
World Health Oragnization
What are some examples of new bacterial threats?
- Ecoli 0157:H7 in food
- lyme disease
- Group A streptococci
- Legionnares disease
- Antibacterial resistance
How does people obtain antibacterial resistance?
- improper medical use
- use in agriculture
-MRSA ( improper use of antibiotics cana lead to antibiotic resistant infections like MRSA)
T o F: Tuberulosis is the second leading cause of infectious disease death worldwide
False: it is the firs leading cause of infectious disease death world wide
what proportion of the world is infected with TB? who is at a higher risk of of getting TB?
1/3 & people with HIV
what is the fatality rate for untreated TB? how is TB transmitted? Are antibiotics effective in treating TB?
50% & it is transmitted through aerosols (droplets that hold on to the pathogen and linger in the air)
- Antibiotics are effective but must be taken for several months
when was there a resurgence of TB in the us?
in the early 1990’s
what is the risk of improperly using antibiotics with TB?
it can lead to antibiotic resistance and multi drug resistance as well as making the mortality rate exceed 50%
wat is the best approach for preventing antibiotic resistance?
directly observed therapy (patients have to take their medication under the surveillance of a medical professional)
what is the public health response to emerging infections?
- Global surveillance on human, domestic animal, and wildlife populations
- agency surveilllance
- institute of Medicine Recommendations:
( new vaccines, new anti microbial dugs, measures against vector based diseases, and banning use of antibiotics for growth promotion in animals)
what agencies are responsible to global surveillance of infectious disease?
- World Health Organization
- CDC - International Emerging Infections Program
- WHO for animal health
- Food and Agricultural Organization for the United Nations
how should public health address vaccine hesitancy? what is the most effective method to address this
carrot, sticks, and sermons
- carrots: prizes for doing th health behavior
- sticks: penal it for not doing the health behavior
- sermon: trying to persuade people to do the health behavior
for vaccinations carrots are the most effective but the others can als be used
what is the leading cause of death and disability in the us?
Chronic Disease,
what are the top two causes of death in the us?
cancer and heart disease
What does chronic disease impact? what are the causes of chronic disease?
- impacts the quality of life severely
- has multiple causes, risk factors are less recognizable
what is the two types of research done on chronic disease?
epidemiological research & Laboratory research
what two leading causes of death in the US does cardiovascular disease encompass?
heart disease and stroke
fill in the blank: ___________ is part of the development of cardiovascular disease
atherosclerosis (narrow and hardened arteries due to plaque build up)
what are the risk factors for cardiovascular disease:
- diet, high blood pressure, diabetes, and smoking all interact to cause injury of the artery walls
- cholesterol level - the lower the better
- (LDL - low is better , HDL- high is better )
- genetics
- exercise (lowers total cholesterol and increases HDL) (smoking decreases HDL)
- use of statins for secondary prevention is widespread
What are plays a role in high blood pressure? what are the ranges for health blood pressure and hypertension stage 1?
- obesity, smoking, stress, and salt
- health blood pressure less than 120/80
hypertension stage one is 130-139/80-89
T or F: secondary prevention is not effective for high blood pressure
false: it is effective
T or False Cancer is more difficult to understand than cardiovascular disease
True
how does cancer arise?
from mutations in DNA caused by chemicals,viruses,and radiation
what causes 1/3 of cancer deaths?
tobacco use
what is diabetes? is it a major cause of disability? what are the different types
deficiency in the ability to metabolize (break down) sugar
- yes diabetes is a major cause of disability
- type 1 diabetes: “childhood onset” - insulin production failure
-type 2 “ adult onset”- insulin resistance
which types of diabetes is risiing in prevelance i the us?
type 2 and it is closely correlated with obesity
what contributes to the seriousness of diabetes as a public health problem?
lack of access to routine medical care
what is a prominent psychological factor that affects our health? Provide examples
stress
- ex: mortalities (death) increases after death of a spouse,loss of a job, divorce, etc.
- ex: stress increases your risk of the common cold and heart disease
- more daily struggles with stress at lower SES
How long can post covid or Long covid conditions last?
they can last weeks, months, or longer
T or F; There are tests available to diagnose post covid conditions
False there are not tests
What are some symptoms of Long Covid?
- fever
- difficulty thinking or concentrating “brain fog”
- heart palpations
chest pains - coughing
-sleep problems - difficulty breathing
Define Teratogens
a substance or agent that causes birth defects
what are some examples of environmental teratogens and their effects?
- alcohol - fetal alcohol syndrome
- drugs: acutane, hormones, cocaine, heroin
- environmental chemicals: ( ex: Minimatas disease in japan due to mercury exposure in the water)
-infectious pathogens: congenital syphilis (syphilis passed to child during birth), rubella, toxoplasmosis
Fill in the blank: genetic materials for humans are located on ___ chromosomes
46
what are two types of genetic diseases (specifically chromosomal abnormalities)
trisomy 21 and down’s syndrome
what is the difference between autosomal dominant, x-linked, and autosomal recessive?
- autosomal dominant: affected person inherits one copy of gene (dominant allele) to express disease and then passes it to all of their children
- autosomal recessive: affected person needs to inherit two copies of a gene
- x - linked: passed on by mother and the disease occurs commonly in males (mother has two XX’s and a males needs one x (ether recessive or dominant) to inherit the disease
Can the severity of genetic conditions be influenced by environment?
yes it can (ex: taking folic acid can reduce the risk of spina bifida in a child)
what influences susceptibility to adulthood diseases?
Genes
are mental disorders genetic?
they are believed to be partially genetic
what two conditions are newborns screened for at birth? can early detection of these conditions prevent or reduce permenant damage?
- PKU and hypothyroidism
- the early detection of PKu and hypothyroidism can prevent or reduce damage
define genomics
how genes act in the body and how they interact with environmental influences to cause disease
what are the benefits of genomic medication?
earlier treatment and increased prevention
what is an example of how genomic medicine relates to cancer genes?
- studying someone’s genome and understanding if their body has barca 1 and brca 2 they are at a genetic predisposition for developing breast cancer.this puts people in a weird ethic dilemma beacause they do not know if finding out will
why is genetic counseling controversial?
because people believe that genetic abnormalities can be unethical to pass on and its kind of the practice of eugenics and choosing the most desirable genetics to pass onto a child
what is the difference between the leading cause of death and the actual leading cause of death?
-the leading cause of death is the diagnosis at the time of death
- the actual leadin cause fo death is the underlying causes of death / root causes
what is the leading cause of death a result of?
combination of external and genetic factors
T or F: the actual leading cause of death is not preventable is and is not the aim of public health interventions
false; the actual leading cause off death is preventable and is the aim of public health interventions