Exam 2 Flashcards
Everything except DM
Input from the 5 senses; can be ignored or perceived and transferred to short memory in <1 second
Sensory memory
Limited capacity
Temporary recall
Processed in 10–15 seconds long-term storage or decay
first to go when there are memory lapses
Short-term memory
Subconscious influence of previously encountered information on subsequent performance
*stays the longest
Implicit (procedural)
Structured facts, meanings, concepts, and knowledge
Explicit– semantic
Autobiographical of events, contextual knowledge, and associated emotions
Explicit– episodic
hyperactive, hypoactive, mixed
Types of delirium
apathy
loss of interest in activities
social withdrawal
isolation
trouble concentrating
impaired thinking
similar features of dementia and depression
dementia is a global impairment impacting intellectual functioning, memory, and at least one of the following
Abstract thinking
Judgment and language
Identification of people and objects
Personality changes
Ability to use object appropriately
associated with cerebrovascular disease
memory loss usually less severe than AD
mood changes
can occur in conjunction with AD–> mixed dementia
key features of vascular dementia
impaired attention, planning
difficulties with complex activities
disorganized thought
symptoms of vascular dementia
complex visual hallucinations
parkinsonism
sleep disturbances
fluctuating cognition
most likely to be misdiagnosed
dementia with lewy bodies
Parkinson’s disease dementia (PDD)
Dementia with Lewy bodies (DLB)
Neuropsychiatric symptoms → DLB
3 presentations of lewy body disease
common in younger groups
memory intact in early stages
changes in behavior and personality
disinhibition and impulsivity are common
types: Pick’s disease, progressive supranuclear palsy, and corticobasal degeneration
frontotemporal dementia
gradual loss of memory and function
eventual inability to recognize friends/ family/ self
majority of cases– 50-60%
Alzheimers disease
repair is disabled by amyloid plaques
Alzheimer’s disease
aggregation of amyloid beta–>
tau tangle formation–>
inflammation–>
synapse dysfunction and cell death–>
dementia
Amyloid Hypothesis
ApoE4 carriers have greater AB deposits than non-carriers
4= greatest risk
2= lower risk
donepezil and memantine
drug options for neurotransmitter depletion
removes beta amyloid plaques from the brain
aducanumab
blocks formation of amyloid beta plaques in the brain
lecanemab
temporal lobe and hippocampus
memory loss
frontal lobe and limbic system
personality/behavior changes
appears normal
stays mentally and physically active
no treatment necessary
no impairment
will begin to experience forgetfulness
no treatment necessary
very mild decline
will begin to notice a change and decline in function
Alzheimers can be diagnosed
mild decline
thinking and reasoning become more obvious and new issues appear
clear s/sx of AD are seen
moderate decline
may experience significant confusion and become agitated
begins to require help with day to day activities
moderately severe decline
may begin to wander
requires assistance/ reminders with ADLs
requires constant supervision
severe decline
loss of ability to respond to environment or communicate
loss of movement and locomotion
disease complication may result in death
very severe decline
no cognitive impairment (NCI)
0
very mild cognitive impairment (MCI)
0.5
mild dementia
1