Exam 2

Question 1

Lecture 1

Question 2

Allergy Monoclonal Antibody - Cytopoint

Answer 2

Canine Atopic Dermatitis
-Itching
-Scratching
-Infections
-Allergy relief
-4-8 weeks
-Safest for long term

MOA
-Blocks IL-31
-95% of clinical symptoms from environmental allergies
-IgE - Th2 cells

Question 3

Antihistamines - Benadryl, Zyrted, Allegra

Answer 3

-20% of cases effective
-Cheap
-Safe
Combine new non-sleep with old sleep antihistamines for best results

Question 4

Which is the best antihistamine in cats? 70% effective

What medication helps with sleep?

What medication helps with nerve pain and it is an antidepressant?

Which treatment helps restore the skin barrier?

Answer 4

-Chlorpheniramine - Antihistamine in cats

-Dextromethorphan - Sleep promoting

-Amitriptyline - nerve pain, antidepressant

-Oats, soothing bath treatment

Question 5

Which medications/treatments have the most adverse effects, but can be used for short burst 3-5 days to reduce severe itch caused by infection (yeast/mites) during the 1-2 week allergy treatment phase? 5-10 itch scale

Answer 5

1. Steroids
   -Demethasone: injectable or oral
2. Apoquel

Question 6

What medication is best antifungal for dogs?

Answer 6

Ketoconazole
-Very safe

Question 7

Which medication is FDA approved anti-fungal for cats? Dermatophyte and yeast infection triggered by diabetes

Answer 7

Itraconazole - Mycrosporum canis
-Oral

Question 8

What antibiotics can be used for dermatology treatments? what is the big concern? How long should the treatment last at minimum?

Answer 8

-21-28 days
Great skin antibiotics usually start with C
-Clindamycin
-Chloramphenicol
-Cephalexin
-Convenia = cephalosporin 3rd generation

Concerns
-MRSA
-Fluroquinolones = Enrofloxacin

Question 9

Should allergic dogs be bathed weekly?
What treatments can help prevent infection?

Answer 9

NO, it is a myth
Weekly is too often

Prevention of infection
-Oat bath
-Soothing and topical barrier repair
Look at the active ingredient

Glycotechnology
-Not as good as advertised
-Long chain sugars to coat the skin

Zin and Silver
-Help a little
-Head and shoulders shampoo

Question 10

Eat Disease - Otitis 3 steps

Answer 10

Step 1

-Clean at clinic
-EpiOtic advanced
-Alcohol flush for swimmers

Step 2 - Wax

-Favorite product EasOtic 1 pump 1ml short acting
-Long acting Claro = florfenicol, terbinafine: use every month
-Short acting or long acting product
-Antibacterial
-Anti yeast
-With steroid

Step 3 - Pus + Pain

-Pseudomonas treatment
-Tris-EDTA 4 oz
-With LA Baytril 12 cc (1000 mg)

Question 11

Cytopoint

Answer 11

MOA
-Selective for Th2
-Reduces immune modulator not suppressor

Question 12

Atopica - Cyclosporine

Answer 12

Immune modulator, not suppressive

-First FDA approved drug non-steroidal
-Takes a while before it works
-1 in 20 dogs vomits