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Virology > Exam 2 > Flashcards

Exam 2 Flashcards

1
Q

Structure of HSV-2 (type of DNA/RNA Structure, Capsid shape, Enveloped or not, extra)

A
  • double stranded DNA
  • icosahedral capsid
  • tegument
  • enveloped
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2
Q

Structure of VZV (type of capsid, type of DNA/RNA Structure), Capsid shape, Enveloped or not, extra?

A

Double stranded DNA
Icosahedral capsid
Tegument
Enveloped

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3
Q

Structure of CMV (type of capsid, type of DNA/RNA Structure), Capsid shape, Enveloped or not, extra?

A

Double stranded Liner DNA
Icosahedral capsid
Enveloped

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4
Q

Structure of Influenza (type of capsid, type of DNA/RNA Structure), Capsid shape, Enveloped or not, extra?

A

8 segments of single stranded RNA
Helical capsid
Enveloped

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5
Q

Structure of SARS-CoV-2 (type of capsid, type of DNA/RNA Structure), Capsid shape, Enveloped or not, extra?

A

Single stranded RNA
Helical capsid
Enveloped

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6
Q

Structure of HEP A (type of capsid, type of DNA/RNA Structure), Capsid shape, Enveloped or not, extra?

A

Single stranded RNA
Icosahedral capsid
Non-enveloped

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7
Q

Structure of HEP B (type of capsid, type of DNA/RNA Structure), Capsid shape, Enveloped or not, extra?

A

Partially double stranded DNA
Icosahedral capsid
Enveloped

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8
Q

Structure of HEP C (type of capsid, type of DNA/RNA Structure), Capsid shape, Enveloped or not, extra?

A

Single stranded RNA
Icosahedral capsid
Enveloped

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9
Q

Structure of HIV (type of capsid, type of DNA/RNA Structure), Capsid shape, Enveloped or not, extra?

A

Single stranded RNA
Cone shaped capsid
Enveloped

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10
Q

Viral Nucleic Acid Organization of HSV-2

A

dsDNA —> dsDNA
Liner genome

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11
Q

Viral Nucleic Acid Organization of VZV

A

dsDNA
Linear Genome

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12
Q

Viral Nucleic Acid Organization of CMV

A

dsDNA
Liner genome

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13
Q

Viral Nucleic Acid Organization of Influenza

A

-ssRNA —> +ssRNA —> -ssRNA
Segmented genome

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14
Q

Viral Nucleic Acid Organization of SARS-CoV-2

A

+ssRNA —> -ssRNA —> +ssRNA
Linear genome

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15
Q

Viral Nucleic Acid Organization of Hep A

A

+ssRNA —> -ssRNA —> +ssRNA
Linear genome

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16
Q

Viral Nucleic Acid Organization of Hep B

A

dsDNA —> +ssRNA —> dsDNA
Circular genome

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17
Q

Viral Nucleic Acid Organization of Hep C

A

+ssRNA —> -ssRNA —> +ssRNA
Linear genome

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18
Q

Viral Nucleic Acid Organization of HIV

A

+ssRNA —> dsDNA —> +ssRNA

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19
Q

Viral Replication cycle happens where in HSV-2

A

Nucleus

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20
Q

Viral Replication cycle happens where in VZV

A

Nucleus

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21
Q

Viral Replication cycle happens where in CMV

A

Nucleus

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22
Q

Viral Replication cycle happens where in Influenza

A

Nucleus

23
Q

Viral Replication cycle happens where in SARS-CoV-2

A

Cytosol

24
Q

Viral Replication cycle happens where in Hep A

A

Cytosol

25
Q

Viral Replication cycle happens where in Hep B

A

Cytosol

26
Q

Viral Replication cycle happens where in Hep C

A

Cytosol

27
Q

Viral Replication cycle happens where in HIV

A

Cytosol and Nucleus

28
Q

Pathology of HSV-2

A

Primary infection in genitals and anus causing genitalia ulcers, fever, headache, muscle aches, and swollen lymph nodes

29
Q

Pathology of VZV

A

Exclusive human virus, causes chicken pox. Reactivation causes: herpes zoster, burning pain in nerves and skin, compromised blood flow, nervous system disorder, retinal necrosis,

30
Q

Pathology of CMV

A

Tissue damage, inflammation in organs, combined immune deficiency (CIDs), hepatitis retinitis, encephalitis, gastrointestinal disease

31
Q

Pathology of Influenza

A

Acute respiratory disease, runny nose, aches and pains, pandemic strains more deadly

32
Q

Pathology of SARS-CoV-2

A

Acute respiratory disease, first time in humans, brain fog, respiratory and fecal shed and spread

33
Q

Pathology of Hep A

A

Acute, gut and liver disease, fecal and oral spread, jaundice

34
Q

Pathology of Hep C

A

Acute and chronic, fatigue, jaundice, liver disease, cancers and failure, virus in blood, EHM, cryoglobulinemia, peripheral neuropathy, immune disorders

35
Q

Pathology of Hep B

A

Acute and Chronic, fatigue, jaundice, abdominal pain and nausea, liver disease, cancers and failure

36
Q

Pathology of HIV

A

Destruction of CD4 T cells, immune deficiency, opportunistic infection

37
Q

Immune evasion of HSV-2

A

Down regulates immune system through mRNA host degradation, latency, blocks MHC

38
Q

Immune evasion of VZV

A

Inhibits Tcells, latency

39
Q

Immune evasion of CMV

A

Blocks NK cells, latency’s

40
Q

Immune evasion of Influenza

A

IFN suppression, shift and drift, antigenic variation

41
Q

Immune evasion of SARS-CoV-2

A

Antigenic variation, IFN suppression

42
Q

Immune evasion of Hep A

A

short incubation period, immune tolerance and exhaustion

43
Q

Immune evasion of Hep B

A

Short incubation period, immune tolerance and exhaustion

44
Q

Immune evasion of Hep C

A

High genetic diversity, escape mutations, immune tolerance and exhaustion, inhibition of INF, shift and drift

45
Q

Immune evasion of HIV

A

Latency, CD4 dependent, quasi species

46
Q

Prevention and treatment of HSV-2

A

Acyclovir, Valtrex

47
Q

Prevention and treatment of VZV

A

Varivax, Zostravax, Shingrex

48
Q

Prevention and treatment of CMV

A

No vaccines

49
Q

Prevention and treatment of Influenza

A

Flu Block, Flu Zone, Flu mist, intenuated/killed vaccines

50
Q

Prevention and treatment of SARS-CoV-2

A

Spike protein braised vaccines,

51
Q

Prevention and treatment of Hep A

A

Inactivated whole virus vaccine

52
Q

Prevention and treatment of Hep B

A

Capsid biased vaccine

53
Q

Prevention and treatment of Hep C

A

No vaccines

54
Q

Prevention and treatment of HIV

A

PrEP (pre-exposure proflaxis

Virology (1 decks)

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