Exam 2 Flashcards

1
Q

Structure of HSV-2 (type of DNA/RNA Structure, Capsid shape, Enveloped or not, extra)

A
  • double stranded DNA
  • icosahedral capsid
  • tegument
  • enveloped
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2
Q

Structure of VZV (type of capsid, type of DNA/RNA Structure), Capsid shape, Enveloped or not, extra?

A

Double stranded DNA
Icosahedral capsid
Tegument
Enveloped

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3
Q

Structure of CMV (type of capsid, type of DNA/RNA Structure), Capsid shape, Enveloped or not, extra?

A

Double stranded Liner DNA
Icosahedral capsid
Enveloped

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4
Q

Structure of Influenza (type of capsid, type of DNA/RNA Structure), Capsid shape, Enveloped or not, extra?

A

8 segments of single stranded RNA
Helical capsid
Enveloped

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5
Q

Structure of SARS-CoV-2 (type of capsid, type of DNA/RNA Structure), Capsid shape, Enveloped or not, extra?

A

Single stranded RNA
Helical capsid
Enveloped

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6
Q

Structure of HEP A (type of capsid, type of DNA/RNA Structure), Capsid shape, Enveloped or not, extra?

A

Single stranded RNA
Icosahedral capsid
Non-enveloped

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7
Q

Structure of HEP B (type of capsid, type of DNA/RNA Structure), Capsid shape, Enveloped or not, extra?

A

Partially double stranded DNA
Icosahedral capsid
Enveloped

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8
Q

Structure of HEP C (type of capsid, type of DNA/RNA Structure), Capsid shape, Enveloped or not, extra?

A

Single stranded RNA
Icosahedral capsid
Enveloped

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9
Q

Structure of HIV (type of capsid, type of DNA/RNA Structure), Capsid shape, Enveloped or not, extra?

A

Single stranded RNA
Cone shaped capsid
Enveloped

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10
Q

Viral Nucleic Acid Organization of HSV-2

A

dsDNA —> dsDNA
Liner genome

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11
Q

Viral Nucleic Acid Organization of VZV

A

dsDNA
Linear Genome

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12
Q

Viral Nucleic Acid Organization of CMV

A

dsDNA
Liner genome

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13
Q

Viral Nucleic Acid Organization of Influenza

A

-ssRNA —> +ssRNA —> -ssRNA
Segmented genome

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14
Q

Viral Nucleic Acid Organization of SARS-CoV-2

A

+ssRNA —> -ssRNA —> +ssRNA
Linear genome

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15
Q

Viral Nucleic Acid Organization of Hep A

A

+ssRNA —> -ssRNA —> +ssRNA
Linear genome

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16
Q

Viral Nucleic Acid Organization of Hep B

A

dsDNA —> +ssRNA —> dsDNA
Circular genome

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17
Q

Viral Nucleic Acid Organization of Hep C

A

+ssRNA —> -ssRNA —> +ssRNA
Linear genome

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18
Q

Viral Nucleic Acid Organization of HIV

A

+ssRNA —> dsDNA —> +ssRNA

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19
Q

Viral Replication cycle happens where in HSV-2

A

Nucleus

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20
Q

Viral Replication cycle happens where in VZV

A

Nucleus

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21
Q

Viral Replication cycle happens where in CMV

A

Nucleus

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22
Q

Viral Replication cycle happens where in Influenza

23
Q

Viral Replication cycle happens where in SARS-CoV-2

24
Q

Viral Replication cycle happens where in Hep A

25
Viral Replication cycle happens where in Hep B
Cytosol
26
Viral Replication cycle happens where in Hep C
Cytosol
27
Viral Replication cycle happens where in HIV
Cytosol and Nucleus
28
Pathology of HSV-2
Primary infection in genitals and anus causing genitalia ulcers, fever, headache, muscle aches, and swollen lymph nodes
29
Pathology of VZV
Exclusive human virus, causes chicken pox. Reactivation causes: herpes zoster, burning pain in nerves and skin, compromised blood flow, nervous system disorder, retinal necrosis,
30
Pathology of CMV
Tissue damage, inflammation in organs, combined immune deficiency (CIDs), hepatitis retinitis, encephalitis, gastrointestinal disease
31
Pathology of Influenza
Acute respiratory disease, runny nose, aches and pains, pandemic strains more deadly
32
Pathology of SARS-CoV-2
Acute respiratory disease, first time in humans, brain fog, respiratory and fecal shed and spread
33
Pathology of Hep A
Acute, gut and liver disease, fecal and oral spread, jaundice
34
Pathology of Hep C
Acute and chronic, fatigue, jaundice, liver disease, cancers and failure, virus in blood, EHM, cryoglobulinemia, peripheral neuropathy, immune disorders
35
Pathology of Hep B
Acute and Chronic, fatigue, jaundice, abdominal pain and nausea, liver disease, cancers and failure
36
Pathology of HIV
Destruction of CD4 T cells, immune deficiency, opportunistic infection
37
Immune evasion of HSV-2
Down regulates immune system through mRNA host degradation, latency, blocks MHC
38
Immune evasion of VZV
Inhibits Tcells, latency
39
Immune evasion of CMV
Blocks NK cells, latency’s
40
Immune evasion of Influenza
IFN suppression, shift and drift, antigenic variation
41
Immune evasion of SARS-CoV-2
Antigenic variation, IFN suppression
42
Immune evasion of Hep A
short incubation period, immune tolerance and exhaustion
43
Immune evasion of Hep B
Short incubation period, immune tolerance and exhaustion
44
Immune evasion of Hep C
High genetic diversity, escape mutations, immune tolerance and exhaustion, inhibition of INF, shift and drift
45
Immune evasion of HIV
Latency, CD4 dependent, quasi species
46
Prevention and treatment of HSV-2
Acyclovir, Valtrex
47
Prevention and treatment of VZV
Varivax, Zostravax, Shingrex
48
Prevention and treatment of CMV
No vaccines
49
Prevention and treatment of Influenza
Flu Block, Flu Zone, Flu mist, intenuated/killed vaccines
50
Prevention and treatment of SARS-CoV-2
Spike protein braised vaccines,
51
Prevention and treatment of Hep A
Inactivated whole virus vaccine
52
Prevention and treatment of Hep B
Capsid biased vaccine
53
Prevention and treatment of Hep C
No vaccines
54
Prevention and treatment of HIV
PrEP (pre-exposure proflaxis