Exam 2 Flashcards
ventilation def
the movement of gas into and out of the lungs
what does adequate spontaneous ventilation require
sufficient Vt, RR, and minute volume to support O2 and CO2 removal, while maintaining acid-base balance
Single best clinical index of ventilation
PaCO2
Hypoventilation, hyperventilation, normal values
Normal 35-45 mmHg
Hypoventilation > 45 mmHg
Hyperventilation < 35 mmHg
anatomic deadspace def (and normal)
vol of gas in conducting airways down to terminal bronchioles
Normal 1mL/ lb IBW (~150mL)
alveolar deadspace (and normal)
alveoli that are ventilated w/o perfusion
Normal 0
what diseases increase alveolar deadspace
deadspace diseases; emphysema and PE
physiologic deadspace def (and normal)
total fxnal DS volume that consists of the alveolar and anatomic DS
VDphys = VDanat + VDalv
Normal phys DS = anat DS
Phys DS > anat DS with DS disease (ex emphysema and PE)
mechanical DS def
volume of rebreathed gas d/t mechanical device (ex ventilator tubing)
alveolar ventilation def (and normal)
vol of gas reaching alveoli that are ventilated AND perfused per min
Normal 4-5Lpm
most common reason for initiating mechanical ventilatory support
acute respiratory failure
what is ventilatory capacity affected by
respiratory drive, lung function, ventilatory workload, and ventilatory muscle strength
ventilatory requirements are determined by
oxygenation status, CO2 production, lung function, circulatory balance, acid base production
causes of ARF
- PNA
- ARDS
- Trauma
- Sepsis
- Post op respiratory failure
- COPD exacerbation
early manifestations of ARF
- Tachycardia
- Tachypnea
- Diaphoresis
- Anxiety
- Respiratory distress
signs of ARF
- Decreased resp drive
- Accessory muscle use
- Intercostal retractions
- Chest wall & diaphragmatic asynchrony
- Decreased chest wall excursion
- Apnea
goals for mechanical ventilatory support
- Provide adequate alveolar ventilation
- Ensure adequate tissue oxygenation
- Restore & maintain acid-basis balance
- Decrease WOB
- Normalize alveolar ventilation & PaCO2
- Correct respiratory & metabolic acidosis
- Reverse hypoxemia
- Relieve respiratory distress
indications for mechanical ventilation
apnea, acute vent failure, impending vent failure, refractory hypoxemia,
what do you do if a peds pt is apneic
check for foreign body aspiration
causes of apnea
cardiac arrest, MI, trauma, shock, OD, spinal cord injuries, neuro disease, general anesthesia, paralytics
acute vent failure def
sudden increase in PaCO2 w a decrease in pH
what pH indicates mech vent needed
pH < 7.25
chronic vent fail def
increase in PaCO2 but pH normal d/t metabolic compensation
impending vent failure def
vent failure likely to occur in immediate future
what does IVF often lead to
elective intubation/ventilation
what do you try before elective intubation
HHF/HFNC for 30-120 mins
wdyd for a COPD pt w IVF and pH > 7.25
BiPAP trial
how to dx refractory hypoxemia
FiO2 increase > 10% & PaO2 increase < 5 mmHg
P/F ratio def
PaO2/FiO2 - measure the effectiveness of O2 transfer across the lung
P/F ratio classifications
- Mild ARDS: P/F 200-300 mmHg (while on PEEP 5)
- Mod ARDS: P/F 100-200 mmHg (while on PEEP 5)
- Severe ARDS: P/F < 100 mmHg (while on PEEP 5)
why do ARDS pts have severe oxygenation problems
increased intrapulmonary right to left shunt
full ventilatory support def
provides 100% of pt’s vent needs
full vent support is available through
VC and PC
types of full vent support
AC/VC, AC/PC, SIMV/VC, SIMV/PC
how does a ventilator (on full support) minimize amt of pt effort
by delivering adequate Vt, RR, and minute volume
can spont breathing pts trigger vent in CMV
YES; if pt goes apneic, vent will deliver set breath
partial vent support def
Requires pt to continue to spont breathe to maintain adequate alveolar ventilation but provides enough support required to maintain good PaCO2
what is partial vent support available through
SIMV
what rate requires pt to breathe on SIMV
RR < 8-10bpm
VC-CMV
all mandatory breaths, pt/time triggered, volume/time cycled
what does the clinician set in VC-CMV
desired Vt, minimum RR, insp peak flow, insp flow waveform, trigger sensitivity
advantages of VC-CMV
i. Constant Vt (even when compliance/Raw changes)
ii. Guaranteed minimum ventilation delivered (d/t set RR and Vt)
iii. Provides full vent support
disadvantages of VC-CMV
i. Unsafe PIPs may occur (d/t reduced compliance or increased Raw)
ii. Unsafe Pplat may occur (d/t inappropriate Vt or reduced compliance)
iii.Improper trigger sensitivity or inadequate flow rates may increase WOB
PC-CMV
all mandatory breaths, pt/time triggered, time cycled
what does the clinician set in PC-CMV
insp pressure, RR, I-time (or insp % time), insp rise time/ramp, trigger sensitivity
advantages of PC-CMV
i. Constant insp pressure
ii. Desired Vt can be achieved by adjusting PIP or I-time