Exam 2 Flashcards
What are different types of movement?
Intracellular, muscle, cell motility/shape
What are the two components of movement?
Cytoskeleton that provides movement and motor proteins that provide movement.
What are microtubules?
Tubulin polymers that conduct intracellular traffic and are part of a dynamic system. Make up cellular components like flagella and cilia.
What is the MTOC?
Microtubule organization center where microtubules of cell are organized from
What is the sliding filament theory?
Myosin pulls actin past itself to cause contraction. Force is generated by muscle shortening and increased cross bridges is directly proportional to tension generation.
What is a sarcomere?
Subunit of striated muscle bundled together in myofilament inside a myofibril.
What are motor units?
Somatic motors neuron and all the muscle fibers it innervates.
What are transverse tubules?
Tubules that carry action potentials deep into the muscle cell and is perpendicular to the myofibril
What is the sarcoplasmic reticulum>
Stores calcium which regulates muscle contraction. Calciums leaves down its gradient via voltage-gated ion channels and reenters through an ATPase pump.
What are myofibrils?
Bundles of actin and myosin.
What is the first step of skeletal muscle contraction?
The somatic motor neuron releases ach
What is the second step of skeletal muscle contraction?
Ach binds receptors which opens channels to cause an action potential
What is the third step of skeletal muscle contraction?
Action potential travels down t-tubules
What is the fourth step of skeletal muscle contraction?
Voltage-gated channels trigger calcium channels on sarcoplasmic reticulum to open
What is the fifth step of skeletal muscle contraction?
Calcium diffuses into cytosol and some binds to troponin.
What is the sixth step of skeletal muscle contraction?
Troponin changes shape and pulls tropomyosin away from binding spots on actin.
What is the seventh step of skeletal muscle contraction?
Myosin heads are able to form cross bridges with actin.
What is the eighth step of skeletal muscle contraction?
The powerstroke cycle occurs with actin being pulled past myosin causing sarcomere shortening.
What is the ninth step of skeletal muscle contraction?
Calcium is pumped back into the sarcoplasmic reticulum by calcium ATPase
What is the tenth step of skeletal muscle contraction?
Troponin releases calcium and tropomyosin slips back over binding spots preventing cross bridge formation.
What is the first step of cardiac muscle contraction?
Pacemaker cells depolarize which generates an action potential
What is the second step of cardiac muscle contraction?
The action potential travels along the conduction pathway and through cells via gap junctions.
What is the third step of cardiac muscle contraction?
Calcium entering as part of the action potential triggers the release of more calcium from the sarcoplasmic reticulum