Exam 2 Flashcards
tuberculosis
Reportable, communicable inflammatory destructive disease
extrapulmonary TB sites (6)
bones, spine, kidneys, reproductive organs, CNS, larynx
facts about mycobacterium tuberculosis
aerobic
acid fast
slow growing, sensitive to heat and UV
destroyed by sunlight, heat, and pasteurization
grows inside the body, not outside
risk factors of TB (gender, age, geographical)
alcoholism r/t malnutrition
elderly
homeless
overcrowded
men
children <15
young adults (15-44 with preexisting conditions)
africa, asia, latin america, europe, carribean
BCG vaccine
makes you test + on skin test
need to do chest x-rays or blood test to get accurate result
routes of TB
airborne (droplet)
inhalation of infected droplet nuclei from COUGHING, laughing, sneezing
large droplets settle, small ones are inhaled
treatment of TB
6-12 months
bed rest until no symptoms
isolation until - sputum
sensitization of TB
phagocytes bombard area with bacteria, lymphocytes start inflammatory response and destroy some lung tissue
2-10 weeks after primary infection
patho of TB
inhaled infected droplet deposited in lungs
inflammatory reaction at site
body attempts to phagocytize the wall-off the tubercule
ghon tubercle formed
granuloma in lung tissue
how can dormant TB become active again
mental and physical stress
immunosuppressive drugs
oncology agents
inadequate drug prescription
latent TB
lives and doesn’t grow
doesn’t make you feel sick
CAN’T spread
active TB
grows in the body
makes you feel sick
CAN spread
sputum culture for TB
identify tubercule bacilli
essential to confirm diagnosis
3 specimens on consecutive days
TB skin test
appearance of “wheal” if done properly
read result within 48-72 hours
10mm or more is +
5-9 is doubtful, repeat
for HIV, 5mm or more is +
what to do with TB converters
they are at risk for developing TB
give INH prevention
TB symptoms (8)
Fatigue
Malaise
Anorexia
Weight loss
Chronic productive cough
Night sweats
Advanced state hemoptysis=blood in sputum
Low grade fever in the late afternoon
primary resistance to TB
resistance to 1 or more TB agents with no previous treatment
secondary resistance to TB
resistant to 1+ TB agent, undergoing therapy
multidrug resistance to TB
resistant to 2+ agents (INH and rifampin)
what to give with INH (TB)
vitamin B6
anti TB drugs
INH, rifampin
pyrazinamide
ethambutol (myambutol)
foods to avoid with INH
Tuna
aged cheese
red wine
soy sauce
yeast extract bc it could have histamine (causes side effects [headaches, diaphoresis, etc] and decreased absorption)
nutrition for TB
high protein, calories, and Ca+
iron and vit B6
labs for TB
AST and ALT
purpose of alveoli
gas exchange
diffusion
separates alveolar from vascular membrane
damage permits exchange between lungs and blood
how much mucus production a day
3 oz
pleura
Lines lungs and thoracic cavity
Kept moist from fluids secreted between pleural surfaces, prevents friction and facilitates filling and emptying of lungs
Secretes pleural fluid–smooth motion of lungs within pleural cavity (air filled so it’s subject to 3rd spacing with pleural effusion)
Depends on mucus and surfactant
when does surfactant develop
34 weeks of gestation
what does surfactant do
facilitates inflation of alveoli
prevents the alveoli from collapsing (keeps them slightly open even when lungs are empty)
tidal volume (what is it, amount, and what effects it)
The amount of air inspired and expired in a normal breath
500 mL
May not vary
total lung capacity (what is it, amount, and what effects it)
the maximum amount the lungs can expand
TV+IRV+ERV+RV (5800 mL)
decreased with atelectasis and pneumonia
increased in COPD
vital capacity (what is it, amount, and what effects it)
the maximum amount of air exhaled after maximal inhalation
TV+IRV+ERV (4600 mL)
decrease in neuromuscular disease, generalized fatigue, atelectasis, pulmonary edema, COPD, and obesity
inspiratory reserve volume (what is it and amount)
the maximum amount of air inhaled after a normal inhalation
3000 mL
expiratory reserve volume (what is it, amount, and what effects it)
maximum amount of air that can be exhaled forcibly after normal exhalation
1100 mL
decreased with obesity, ascites, pregnancy
residual volume (what is it, amount, and what effects it)
volume of air remaining in lungs after maximum exhalation
1200 mL
may be increased with obstructive disease
inspiratory capacity (what is it, amount, and what effects it)
maximum amount of air inhaled after normal expiration
TV+IRV (3500 mL)
decrease in restrictive disease or obesity
functional residual capacity (what is it, amount, and what effects it)
amount of air remaining in lungs after normal expiration
ERV+RV (2300 mL)
may be increased in COPD
decreased in ARDS and obesity
what do accessory muscles do
get rid of trapped air and increase tidal volume
Why does pursed lip breathing work
increases exhalation time to reduce airway resistance and prevent airway collapse
How often to do diaphragmatic breathing
5x/hour for 1 minute with 2 min rest periods