Exam #2 Flashcards
what inhibits sodium transport in the thick ascending loop of henle?
Loop diuretics such as
bumetanide, furosemide, torsemide and etacrynic acid
What drug produces diuresis by increasing renal tubular osmotic pressure
Mannitol
Which is true about diuretics
Spironolactone may help decrease/reverse aldosterone evoked cardiac hypertrophy in CHF patients
Diuretcs are therapeutic for
treat and manage HTN
treat and manage ascites
remove pulmonary edema
enhance renal excretion of a toxic drug
What drug produces metabolic acidosis with continued use?
Acetazolamide
What drug reduces urine output in patients with central diabetes insipidus?
Desmopressin
a patient has been taking lasix for 5 months, what is a side effect of chronic diuresis?
hypokalemia
What causes HTN and decreased preload by stimulating synthesis and release of vasodilatory prostaglandins?
Furodemide
Why should you not take asprin with loop diuretics?
because asprin blocks prostaglandin release
Diuretics are used therapeutically for
to lower arterial BP
to remove pulmonary edema
to increase excretion of toxic drugs
to reduce ascites fluid in pts with hepatic cirrhosis
the use of diuretics with digoxin to treat CHF can lead to
a reduction in blood volume and loss of potassium
which drug is used to prevent the renal tubular re-absorption of sodium caused by high blood levels of aldosterone?
spironolactone
HTCZ acts in the ________ to prevent the renal tubular absorption of sodium
the early portion of the distal convoluted tubule
Chronic use of _____ may cause hypokalemia
furosimide
which of the following it true regarding the use of Mannitol?
readily filtered at the glomerulus, does not cross the blood brain barrier, is not absorbed following oral administration, and is an osmotic diuretic
