Exam 2 Flashcards
Normal Fasting glucose levels
In glucose intolerance
<90
100 - 125
Fetal/newborn complications of diabetes in pregnancy
Birth defects
Macrosomia (large birth weight)
Stillborn
Hypoglycemia
Respiratory distress syndrome
Higher lifetime risk of obesity & glucose intolerance
Insulin requirements during pregnancy
1st trimester
2nd & 3rd
Labor
hPL is
1st - decrease in need for insulin (minimal fetal needs & low hPL)
2 & 3 - increased insulin requirements (placental maturation & high hPL)
Labor - increased energy = increased insulin needs
Human placental lactogen
OGTT is
What levels indicate GDM
What HbA1C level is a risk for GDM
Oral glucose tolerance test
Fasting > 95
75g 1Hr GTT > 180
75g 2Hr GTT > 153
- A1C greater than 7%
Maternal HIV transmission
How to treat HIV
Reduce instrumentation of what during labor
- Vertical transmission to baby through pregnancy, birth & breastfeeding (perinatal transmission)
- Treat with antiretroviral therapy AZT (start at 14 weeks till birth & IV during labor)
- episiotomies & fetal scalp electrodes
Gestational HTN is
How to diagnose
- Onset of HTN without proteinuria after 20th week (normal BP prior)
- BP of 140/90 on 2 counts 4-6hrs apart
Preeclampsia is
Risk factors
- HTN after 20 weeks with proteinuria
- primigravidity, obesity, preexisting medical condition, multi fetal pregnancy
Severe preeclampsia is
Signs/symptoms
Treatment
Management
BP > 160/110
- headache, blurred vision, oliguria, pulmonary edema, Epigastric pain
- Control BP, prevent seizures (quiet environment, sedatives), mag sulfate for neuro protection (baby)
- Assess vision & LOC, DTRs, edema, lung sounds… protect from injury
What is eclampsia
Signs & symptoms
Management
Preeclampsia with seizure activity or coma
- headache, blurred vision, epigastric pain, altered mental status, tonic-clinic convulsions, coma
- ensure patent airway, administer O2, fetal monitoring, mag sulfate
HELLP syndrome stands for
What is it
Betamethasone indication
Hemolysis, elevated liver enzymes, low platelets
- life threatening (high death risk) obstetric complication, clinically progressive
Hepatic dysfunction
- used to stimulate lung maturity in fetus
Magnesium sulfate is
administered by & therapeutic lvl
Toxicity & Antidote
Signs & symptoms of toxicity
Used to prevent seizures
- always IVPB & maintain therapeutic level 4-7
- >8 meq & antidote is calcium gluconate
- hyporeflexia, respiratory depression, decreased urine output, hypotension, cardiac arrest
Alpha-Fetoprotein analysis (AFP) detects what problems
Elevated vs low
Elevated AFP - neural tube defects, hydrocephaly, Turners syndrome
Low AFP - Down’s syndrome (trisomy 21)
Amniocentesis is
Preparation
Management
Danger signs
Collection of amniotic fluid for analysis
- no special diet restriction, stop anticoagulant meds, empty bladder, fetal monitoring, rhogam (for rh-)
- monitor vitals & fetal monitoring, observe puncture site, rest
- fever, leak of amniotic fluid, vaginal bleeding
Chorionic villus sampling (CVS) is
Potential risk
Diagnostic test for chromosome abnormalities & other inherited disorders (cannot detect neural TD)
- bleeding & hemorrhage, miscarriage, infection, digital or limb deficiency
Nonstress test (NST)
Reactive
Non-reactive
Indirect measure of uteroplacental fxn
- 2 FHR accelerations from baseline of at least 15bpm for at least 15 seconds
- absence of 2 FHR accelerations using 15 by 15 criteria in a 20 min time frame