Exam 2 Flashcards

1
Q

Who took pollution serious and issued the 1st antipollution law

A

Edward I

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2
Q

Who was the “mother of smog research”

A

Mary Ander

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3
Q

What created the Donora Smog of 1948 resulting in 21 deaths?

A

Hydrogen fluoride from factories

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4
Q

What was the correlation of deaths and the London fog?

A

Sulfur dioxide spikes

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5
Q

Principal function of the lung is _____

A

gas exchange

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6
Q

What is the surface area of the lungs equate to?

A

Half the size of a tennis court

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7
Q

Difference between inhalation and pulmonary toxicology

A

Inhalation: deals with route of exposure
Pulmonary: only effects on the lung; site of toxicity

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8
Q

Where can the most exposure be found in the conducting airways of the lungs?

A

Bronchioles regions

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9
Q

What is the better name for clara cells?

A

Club cells

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10
Q

Which cell type functions to protect the bronchial epithelium?

A

Clara cells

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11
Q

Which cell type secretes pulmonary surfactant?

A

Type 2 Alveolar Cells

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12
Q

Mixture of lipids and proteins that increase the ability of the lung to expand and also stops it from collapsing at the end of expiration

A

surfactant

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13
Q

What shape cells are type 2 alveolar cells?

A

cuboidal

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14
Q

Expansion of the thoracic cavity by contraction of the _______

A

diaphragm

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15
Q

Relaxation of the diaphragm and contraction of the _________

A

internal intercostal muscle

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16
Q

Inspirations is an (active/passive) process, expiration is an (active/passive) process

A

active, passive

17
Q

In boyles law, volume and pressure are ____ related

A

inversely

18
Q

Approximately 5700cm3 of air is required to reach _ _ _

A

TLC (total lung capacity)

19
Q

Volume that resides in the lungs after expiration

A

Residual volume (RV)

20
Q

Volume of air that is moved in and out of the lungs

A

Vital capacity (VC)

21
Q

Fraction of air moving in and out during rest

A

tidal volume (TV)

22
Q

During heavy oxygen demand what two fractions can increase?

A

Tidal volume and respiratory rate

23
Q

TLC (total lung capacity)=

A

VC (vital capacity) + RV (residual volume)

24
Q

What test measure the ability to move air in and out of the lungs, allowing a diagnosis of obstructive and restrictive diseases?

A

Spirometry