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Calculations > Exam 2 > Flashcards

Exam 2 Flashcards

1
Q

What is a dose?

A

The amount of drug taken by a patient to bring the desired effect

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2
Q

What is the standard dose?

A

The amount of drug that produces the desired effect in the majority of the population

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3
Q

What is the usual dosage range?

A

The dose range determined to be safe and effective

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4
Q

What is a single dose?

A

The amount taken at one time

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5
Q

What is a daily dose?

A

Total dose per day

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6
Q

What is the total dose?

A

The amount taken during the course of therapy

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7
Q

What is the dosing regamin?

A

Schedule of dosing

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8
Q

What is the dosage form?

A

Finished pharmaceutical product (drug in tablet, capsule, etc.)

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9
Q

What kind of dosage form makes up the bulk of solid dosing forms?

A

Capsules and tablets

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10
Q

What kind of release forms are available for capsules and tablets?

A

Immediate release
Extended release
Controlled release

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11
Q

A prescription comes in for Gabapentin (capsule) 600mg but your pharmacy only has Gabapentin 300mg. What can you do to satisfy this prescription?

A

Double the quantity

If 1 capsule once daily make it two capsules once daily

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12
Q

If a prescription comes in for Ibuprofen 600mg but your pharmacy only has Ibuprofen 800mg how can you satisfy this prescription? (there is no scoring on the pill)

A

You cannot since you only have a higher dose of the original dose

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13
Q

A patient comes in for a standard release tablet but he cannot swallow pills whole. He asks you if he can crush this pill so he can take it as a powder. Is this okay?

A

Yes he can since it is standard release (if it was extended release he could not)

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14
Q

What are all the ways this tablet could be broken into without messing up the amount of drug in the dosage form?

A

1/4
1/2
3/4

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15
Q

What are the main oral liquid dosage forms?

A

Syrups
Elixers
Suspension

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16
Q

You have a suspension with a strength of 400mg/5mL. How much drug is in a 100 mL bottle?

A

400x100= 40000/5 =8000mg or 8 grams of drug

17
Q

A patient picks up a prescription for a suspension. You ask if they need a syringe or measuring spoon to use for taking the medication. They tell you no because they have a kitchen teaspoon at home. Is this okay?

A

No - household spoons are not advised by the FDA for dosing

18
Q

What is a fixed dose combination (FDC) product?

A

A single product that contains two or more active ingredients in a fixed dose ratio
(this decreases the flexibility of changing doses but increases the patient’s compliance because they do not have to take separate pills)

19
Q

What kind of drugs dose based off BSA?

A

Anti-cancer
Immunologic (biological)
Some pediatric dosing

20
Q

What is the BSA equation?

A
21
Q

What is the baseline BSA for an average adult?

A

1.73 m^2

22
Q

When would dosing need to be based on Creatinine clearance?

A

When renal function is a factor

23
Q

What is the potency of a drug?

A

Comparative for relative strength of drug to the reference standard to produce the same drug effect

24
Q

What happens during dose titration?

A

The drug doses are adjusted until the desired clinical effect is achieved

25
Q

What does equipotency do?

A

Finds the equivalent doses between 2 different drugs with the same effect

26
Q

What can the equinanalgesic dosing chart be used for?

A

Determine appropriate dose of new drug to be used

Determine appropriate dose of the new Route for the current or new drug

27
Q

What is the fraction sodium excretion? (FENA)

A

The percentage of the sodium filtered by the kidney which is excreted in the urine

28
Q

What does FENA do?

A

Gives an indication of whether renal disease is present

29
Q

What is the single dose?

A

1000 mg

30
Q

What is the daily dose?

A

2000 mg (1000 mg twice daily)

31
Q

What is the total dose?

A

60,000 mg (1000 mg taken 60 times)

32
Q

What is the dosage regimen?

A

twice daily for 30 days

33
Q

What is the dosage form?

A

Tablets

Calculations (1 decks)

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