EXAM 2 Flashcards
Interrupting which herb after taking it for a long time may result in difficulty sleeping, headaches, joint pain, nervousness, and stiff muscles?
- ) Boswellin
- ) Butterbur
- ) Devil’s claw
- ) Feverfew
4
Indicate whether the statement fits the description of ginkgo biloba, St. John’s wort, or both:
- ) Plant part(s) used: leaf only
- ) Plant part(s) used: leaf and flowers
- ) Clinically-proven preparations are 35-67:1 concentrates
- ) Extracts contain phytochemicals from the flavonoid family
Choices:
A.) Ginkgo biloba
B.) St. John’s wort
C.) Both Ginkgo biloba and St. John’s wort
- ) Ginkgo biloba
- ) St. John’s wort
- ) Ginkgo biloba
- ) Both Ginkgo biloba and St. John’s wort
Which constituent of ginkgo must be removed because it has been shown to incite allergic responses and other toxic reactions?
- ) bilobalides
- ) kaempferol glycosides
- ) ginkgolic acids
- ) ginkgolides
3.) ginkgolic acids
On which two families of constituents are medicinal ginkgo extracts standardized?
- ) vanillic acids
- ) hydroxykynurenic acids
- ) flavonoid glycosides
- ) terpene lactones
- ) flavonoid glycosides
4. ) terpene lactones
Distinguish between the pharmacological effects of ginkgo biloba and St. John’s wort
- ) Inhibits synaptic reuptake of neurotransmitters
- ) Upregulates 5-hydroxytryptamine receptors
- ) Increases tolerance of brain tissue to hypoxia
- ) Inhibits platelet activation factor (PAF)
- ) Increases skin response to the effects of UV radiation
- ) Inhibits age-related decline of choline and alpha-adrenergic receptors
Choices:
A.) Hypericum perforatum (St. John’s Wort)
B.) Ginkgo biloba
- ) Hypericum perforatum
- ) Hypericum perforatum
- ) Ginkgo biloba
- ) Ginkgo biloba
- ) Hypericum perforatum
- ) Ginkgo biloba
The German Commission E determined that ginkgo extracts were indicated for all of the following except _____________.
- ) cognitive deficits due to organic brain disease
- ) prevention of stroke
- ) intermittent claudication
- ) vertigo or tinnitus, if due to vascular or involutional etiology
2.) prevention of stroke
T/F: Only St. John’s wort extracts with moderate to high hyperforin content have been found effective in clinical trials
False
T/F: The placebo effect probaby accounts for at least 50% of the beneficial effects of St. John’s wort on depression
True
T/F: Lower cost and fewer adverse effects are two distinct advantages of either ginkgo or hypericum extracts over pharmaceutical medicines typically prescribed for dementia or depression, respectively.
True
T/F: Marked improvement in depressive symptoms can be expected to occur within one to two weeks of therapy with hypericum extracts.
False
St. John’s wort may interact significantly with which of the following types of drugs? (Choose the most complete answer)
- ) All of these
- ) Anticoagulants
- ) Protease and reverse transcriptase inhibitors
- ) Two of these
- ) Immunosuppressants
- ) Selective serotonin reuptake inhibitors (SSRIs)
1.) All of these
Match the common name with the Latin binomial:
- ) Kava
- ) Hops
- ) Lemon balm
Choices:
A.) Humulus lupulus
B.) Piper methysticum
C.) Melissa officinalis
- ) Piper methysticum
- ) Humulus lupulus
- ) Melissa officinalis
Match the herb with the plant part(s) primarily used:
- ) Kava
- ) Valerian
- ) Lavender
- ) Hops
- ) Lemon balm
- ) Passion flower
Choices: A.) strobiles (female flowers) B.) rhizome C.) aerial parts, including fruits D.) flowers only, any gender E.) leaf F.) root
- ) rhizome
- ) root
- ) flowers only, any gender
- ) strobiles (female flowers)
- ) leaf
- ) aerial parts, including fruits
Match the herb with its active constituent(s) or the biochemical families the constituent(s) belong to:
- ) sesquiterpenes
- ) linalyl acetate and cineol
- ) pyrones
- ) humulone and lupulone
Choices: A.) Lavender B.) Hops C.) Kava D.) Valerian
- ) Valerian
- ) Lavender
- ) Kava
- ) Hops
Which medicinal herb has been studied primarily as aromatherapy?
- ) Valerian
- ) Lavender
- ) Lemon balm
- ) Hops
- ) Passion flower
2.) Lavender
Which potential adverse reaction to kava has led to a product recall in Europe and a public warning issued by the US FDA?
- ) Teratogenicity
- ) Liver damage
- ) Carcinogenicity
- ) Kidney damage
2.) Liver damage
T/F: Aqueous and ethanol extracts of valerian root are equivalent in the quality of their actions.
False
Which subspecies of Valerian is recommended for use in valerian preparations?
- ) indica
- ) officinalis
- ) edulis
- ) japonica
2.) officinalis
Valerian products with a high content of which constituent should not be used due to potential toxicity?
- ) Valerenic acid
- ) Acetoxyvalerenic acid
- ) Valepotriates
3.) Valepotriates
Upon which neurotransmitter does Valerian appear to exert its pharmacological effects?
- ) Gamma-aminobutyric acid (GABA)
- ) Acetylcholine
- ) Dopamine
- ) Norepinephrine
1.) Gamma-aminobutyric acid (GABA)
T/F: At least one human study has demonstrated that valerian extract had no adverse effects on the reaction time, alertness, or concentration.
True
T/F: Patients with sleep disturbances can expect to achieve improvement after only a few days of valerian use.
False