Exam 2 Flashcards
What is ATP, how is it formed, and how does it provide energy during metabolism?
ATP is a high energy compound in the body, the usable form of energy derived from food. It is used during exercise as fuel.
What is the primary substrate used to provide energy at rest? During high-intensity exercise?
At rest, carbs and fats are almost equally broken down for energy. During high-intensity exercise, more carbs are used than fats to generate ATP.
What is the role of PCr in energy production, and what are its limitations? Describe the relationship between muscle ATP and PCr during sprint exercise.
Energy from PCr can be used to add a Pi molecule to ADP, forming ATP.
During sprint PCr decreases bc it is donating phosphates to ATP.
Describe the essential characteristics of the three energy systems?
ATP-PCr System- anaerobic, Pi separate from PCr by creatine kinase Pi combines with ADP and forms ATP using energy from PCr breakdown, main function is to maintain ATP levels early in exercise, energy yield= 1 mole ATP per 1 mol PCr Glycolytic System (glycolysis)- anaerobic, glucose/glycogen broken down to pyruvic acid. Pyruvic acid converted to lactic acid when no 02, energy yield= 1 mole glucose yields 2 mol ATP; 1 mol glycogen yields 3 ATP Oxidative system(oxidative phosphorylation)- aerobic, glycolysis, krebs cycle, etc, and yields- H20, CO2, 32-33 ATP per carb molecule
Why are the ATP-PCr and glycolytic energy systems considered anaerobic?
They don’t need oxygen to produce energy. ATP-PCr and glycolytic systems are major contributors of energy during short-burst activities.
What role does oxygen play in the process of aerobic metabolism?
Oxygen is used in the final step of cellular respiration as the final electron acceptor, and is used to create water. Without it only glycolysis can occur.
What is lactic acid, and why is it important?
Pyruvic acid is converted directly to lactic acid in the absence of oxygen. Acid decreases the fibers’ calcium-binding capacity and may impede muscle contraction.
Discuss the interaction among the three energy systems with respect to the rate at which energy can be produced and the sustained capacity to produce that energy.
ATP-PCr: up to 15 seconds of energy, 1 ATP per molecule of substrate, PCr to Cr, and anaerobic
Glycolysis: approx. 1 min of energy, 2-3 ATP per molecule substrate, glucose/glycogen to lactate, anaerobic
Oxidative Phosphorylation: approx. 90 min of energy, glucose/glycogen to CO2 and H2O, aerobic
What is meant by the crossover concept, and how does it change with endurance exercise training?
The cross over concept in relation to exercise intensity is the idea that the balance of fat and carbs utilization during exercise depends on the interaction between exercise intensity
How do type I muscle fibers differ from type II fibers in their respective oxidative capacities? What accounts for those differences?
Muscle fiber I fibers have more mitochondria and a higher concentration of oxidative enzymes compared to type II fibers, known as the fast-twitch fibers, fiber 5 fibers are better suited for glycolytic energy production since they need it faster
Metabolic reactions that do not require oxygen?
anaerobic metabolism
A simple sugar that is the body’s primary fuel source during exercise.
glucose
These are created within the mitochondria then there is excess oxygen and they can negatively affect cell function
reactive oxygen species
The enzyme that catalyzes the reaction that produces ATP from PC, ADP, and Pi
creatine kinase
Metabolic reactions that result in the synthesis of molecules
anabolism
Basic fuel sources, such as CHO, PRO, and fats
substrates
The storage form of glucose in the muscle and liver
glycogen
The breakdown of glucose to pyruvic acid
glycolysis
The process of breaking down a triglyceride to its basic units to be used for energy
lipolysis
A high-energy phosphate compound from which the body derives its energy
ATP
Metabolic reactions that result in the breakdown of molecules
catabolism
A series of chemical reactions that involve the complete oxidation of acetyl CoA to produce 2 mol of ATP along with hydrogen nd carbon, which combine with oxygen to form H2O and CO2
krebs cycle