Exam

Question 1

Suprabasal split

Answer 1

Pemphigus vulgaris
Hailey-Hailey
Dariers disease
FAD / warty dyskeratoma / acantholytic acanthoma
Grover’s disease

Question 2

Subepidermal split w infl

Answer 2

Bullius pemphigoid (eos, antigen BP230 and BP180, linear IgG and C3)
Other eos: bullous drug, bullous arthropod, herpes gestationis)
If nts:
Linear IgA (linear IgA, drugs vancomycin)
Dermatitis herpetiformis (transglutaminase, gran IgA)
Bullius lupus (gran, full house)
Cicatricial pemphigoid (mucous membrane)
Sweet’s and nt dermatoses
If lymphs:
bullous LP

Question 3

Subepidermal split wo infl

Answer 3

Epidermolysis bullosis acquisita (antibodies to collagen 7)
Cell-poor bullous pemphigoid
Porphyria cutanea tarda (hereditary with mutation in uroporphyrin, or acquired)
Pseudo PCT (drug related)
Amyloidosis

Question 4

Psoriasiform w superf epid pallor

Answer 4

Acrodermatitis enteropathica
Pellagra
Necrolytic migratory erythema
Necrolytic acral erythema

Question 5

Lobular panniculitis

Answer 5

A1AT
Pancreatic panniculitis
Lupus panniculitis
SPLTCL
Subcut fat necrosis of newborn
Steroid panniculitis

Question 6

Erythroderma - SCALP-ID

Answer 6

Sezary syndrome
Contact dermatitis
Atopic dermatitis
Lymphoma/leukemia
Psoriasis/PRP
Idiopathic/ichthyosis
Drug (gold, penicillin)

Question 7

Perforating disorders

Answer 7

Elastosis perforans serpiginosa (Down syn, Ehlers-Danlos, PXE and penicillamine)
Reactive perforating collagenosis
Perforating folliculitis (renal impairment)
Kyrle disease

Question 8

Palisading gran infl

Answer 8

Necrobiosis lipoidica
Gran annulare
Necrobiotic xanthogranuloma
Rheumatoid nodule
Epith sarcoma
Palisading and neutrophilic gran derm
Infection

Question 9

Non necrotic gran infl

Answer 9

Sarcoid
Infx (TB, lepromatous leprosy, tuberculoid leprosy)
Foreign body : zirconium and beryllium, talc, gout, rupt EC, triamcinolone, tattoo, paraffinoma

Question 10

Xanthomatous gran infl

Answer 10

Xanthelasma (no lipid abn)
Xanthogranulomas (touton giant cells)
Rosai Dorfman (s100, CD68, plasma cells)
Reticulohistiocytoma
Lipid abnormalities:
Eruptive xanthoma
Tuberous xanthoma
Xanthoma

Question 11

Spongiosis w eos

Answer 11

Herpes gestationis
Arthropod
Allergic
Atopic
Pemphigus
Pemphigoid
Incontinentia pigmenti
Eosinophilic folliculitis
Erythema toxicum neonatorum

Question 12

Spong w parakeratosis

Answer 12

Pityriasis rosea
EAC
Psoriasis

Question 13

Subcorneal split

Answer 13

Pemphigus foliaceus
Pemphigus erythematosus
SSSS
Bullous impetigo

Question 14

Interface vacuolar w dyskeratosis

Answer 14

EM/SJS/TENS
GVHD (hypergranulosis, involving hair follicle)
FDE

Question 15

Interface lichenoid

Answer 15

LP
LPLK
lichenoid drug (parakeratosis, eos)

Question 16

Dermal infl w a Grenz zone

Answer 16

Gran faciale
Lepromatous leprosae
B cell lymphoma

Question 17

Neutrophilic dermatoses

Answer 17

Sweet’s
EED
Gran and nt palisading dermatoses
IBD assoc infl derm

Question 18

Sclerotic dermis

Answer 18

Scleroderma/morphea
Radiation dermatitis

Question 19

Dermal mucin

Answer 19

Scleredema
Scleromyxedema/lichen myxedematosus
Pretibial myxedema
Papular mucinosis

Question 20

Intracorneal pustule

Answer 20

Pustular psoriasis
AGEP
Sneddon-Wilkinson disease
IgA pemphigus
Pemphigus foliaceus
Infantile acropustulosis
Miliaria
Bullous impetigo
SSSS

Question 21

Palmoplantar keratoderma

Answer 21

Diffuse/focal/punctate
Hereditary/acquired (more common)
Inherited: ichthyosis, EB
Acquired:
Vascular - lymphoedema
Infx (tinea, scabies, warts, syphilis)
Infl (PRP, psoriasis, eczema)
Trauma (callus)
Iatrogenic - drugs (BRAF inhibitors)
Neoplastic - internal cancer