Exam 1 Week 1 Flashcards
What is Maternal Morbidity? How is measured?
:A condition outside of normal pregnancy, labor, and childbirth that negatively affects a woman’s health during those times
-per 1,000 live births
What is Maternal Mortality? How is it measured?
:Pregnancy related deaths that occurred during or within 1 year following pregnancy resulting from complications of pregnancy itself
-per 1,000 live births
PRMR stands for =
Definition =
Pregnancy related mortality ratios
of pregnancy related deaths per 1000 live births
of deaths in first 28 days of life/1000 live births =
Neonatal Mortality
of deaths within 1st year of life/1000 live births =
Infant Mortality
of stillborns and deaths in the first week of life/1000 births
Perinatal Mortality
Preterm Neonates Categories 1) 2) 3) 4)
1) Very premature
2) Moderately premature
3) Late preterm
4) Term
___ weeks is minimum to reach viability, or fetal weight greater than ____
24
500g
Very Premature =
less than 28 weeks
Moderately Premature =
28-34 weeks
Late Preterm
34 wks 0/7 days - 36 wks 6/7 days
Term
anything between beginning of 38-42 wks
Neonatal birth weight categories 1) 2) 3) 4) 5)
1) Extremely low birth weight
2) Very low birth weight (VLBW)
3) Low birth weight (LBW)
4) Normal birth weight
5) Macrosomia (High/excessive) birth weight
6 aspects of child birth that are changing with time?
1) Birth Environment
2) Involvement of fathers/significant others
3) Labor Pain Management
4) Induction/Interventions
5) C-sections
6) Postpartum care
What is considered Normal Birth Weight?
2500 - 4000g
What is considered Macrosomnia (High/excessive) Birth Weight?
> 4000 g
What are the two major factors of poor neonatal health outcomes?
- Prematurity
- Low birth weight
What is considered preterm?
prior to the END of 37th week of gestation
What is considered Early Term?
37 wks 0/7 days - 38 wks 6/7 days
Some goals for Healthy People 2020
- Dec fetal and infant deaths
- Dec in maternal mortality rates
- Dec in cesarean births
- Dec in low birth weight neonates
- Dec in use of tobacco and illicit drugs during pregnancy
- Inc in maternal prenatal care
- Inc in number of mothers who breastfeed
Where does fertilization take place?
ampulla of the fallopian tube
The union of the ovum and sperm forms a zygote (46 chromosomes) by the process of _______
Meiosis
Once the zygote is formed what happens?
A series of mitotic cell divisions take place
Cleavage cell division continues to form a _____ : a mass of ___ cells
Morula, 16
The inner cell mass is called a _______ which forms the _____ and _____
Blastocyst
Embryo, Amnion
The outer cell mass called the _______ forms the ______ and _____
Trophoblast
Placenta & Chorion
Implantation occurs __-__ days after conception in the ______
7-10 days
endometrium
After implantation, the endometrium becomes the ______ (______)
Decidua (placenta)
What is considered the embryonic stage? Why is it significant?
During implantation to 8 weeks
During this stage organogenesis occurs
What things can impact organogenesis (3)? During which time?
1) Risk of malformation
2) Teratogen exposure
3) Infection exposure
During embryonic stage aka from implantation to 8 weeks
When does the embryo become a fetus?
at 9 weeks
What is the fetal tissue called?
Chorionic villi = vascular processes of the chorion of the embyro entering the formation of the placenta
What are the two tissues of the placenta?
Maternal Tissue and Fetal tissue
Chorionic villi acts as the area of _____ between the maternal and fetal _____, and has the same genetic material as the _____ cells
exchange, circulation, fetal
What is the term for the maternal tissue of the placenta that is part of the endometrium?
Decidua Basalis
What are the Cotyledons?
The separations of the decidua basalis
Which side of the placenta is more beefy and vascularized?
Maternal tissue
When the placenta is expelled how do you which side is which?
The DULL side is the maternal decidua
The SHINY side is the fetal mebranous side
What are the functions of the placenta?
1) Metabolic and gas exchange
2) Hormone production
3) Amniotic fluid regulation
5) Cushion and sock absorption
The umbilical cord is made out of what?
2 Arteries, 1 vein (AVA), and covered in Wharton’s Jelly
What is the function of Wharton’s Jelly?
It is a gelationous substance that covers, provides insulation, and protects the umbilical cord from compression
What is the purpose of the vein and arteries of the umbilical cord?
Umbilical vein brings oxygenated blood to baby
Umbilical arteries take DE-oxygenated blood away from the baby
2 types of amniotic membranes-purpose and location?
Amnion-inner membrane near the baby, produces the amniotic fluid
Chorion-outer membrane further from the baby, toward the mom
What are the two amniotic fluid abnormalities?
1) Polydramnios
2) Oligohydramnios
What is the Ductus Venosus?
What does it bypass?
This is the duct that shunts a portion of the blood from the umbilical vein directly to the inferior vena cava
Bypassing the LIVER
What is the Foramen Ovale?
What does it bypass?
The opening between the left and right atrium that allows blood to flow straight to left atrium by
Bypassing the LUNGS
What is the Ductus Arteriosus?
What does it bypass?
Vessel that shunts blood from pulmonary artery straight to the aorta and to the circulation
Bypassing the LUNGS
What is the process of fetal circulation?
1) The umbilical vein carries oxygenated blood from the maternal side of the placenta
2) Crosses through the ductus venosus into the inferior vena cava and then to right atrium
3) Crosses the Foramen ovale from right atrium to left atrium
4) Some blood is pumped to the pulmonary artery passing a small amount of blood to the lungs-just enough to supply organ/stimulate growth
5) The larger portion of blood passes from the pulmonary artery though the patent ductus arteriousus into the descending aorta, and into circulation
6) Finally blood returns to placenta through the two umbilical arteries and process is repeated
How long is pregnancy? Days, weeks, months?
280 days, 40 weeks, 10 months
Once the zygote starts to move, it takes ___ days to reach the endometrial cavity.
3
Ovum is thought to be fertile for how long?
Once fertilized it will begin to secrete ______
6-24 hours
hCG
Explain the “all or none” theory
During the first 14 days, terotogenic exposure will either cause death of the embryo or nothing at all.
What is the window of greatest vulnerability for the embryo?
15-60 days, when major organogenesis occurs
Why is exchange across the placenta minimal in the first 3-5 months?
due to thickness and decreased permeability which gradually increases until final month when placenta begins to age
When does the completion of maternal placental and fetal circulation occur?
17 days after conception (when the embryonic heart begins to function)
When does the placenta develop into its own discrete organ? (having both transport and endocrine functions)
14 weeks
What caused the umbilical cord to appear twisted or spiraled?
utero fetal movement
What is nuchal cord?
When the umbilical cord encircles the infant’s neck
amount of amniotic fluid at 10 weeks? after 20 weeks?
30 cc, 700-1000cc
Color of normal amniotic fluid?
What is Meconium? What could it indicate?
Clear
First feces of an infant, makes fluid dark green/brown which could also indicate fetal distress
Production of fluid varies by
excreting and swallowing by fetus
Functions of amniotic fluid
Cushions, Thermoregulation, freedom of movement for musculoskeletal development, and keeps umbilical cord free of compression
Polyhydramnios
What 3 abnormalities is it associated with?
> 2000 ml at term
Maternal/fetal issues -
1) maternal diabetes
2) neural tube defects,
3) chromosomal deviations or malformations of CNS or GI tract that prevents normal swallowing of amniotic fluid by fetus