Exam 1 Study Guide - Lab Flashcards
Dissolution of the drug
pharmaceutic
Effect of drug action because of hereditary influence
pharmacogenetics
Four processes of drug movement to achieve drug action
pharmacokinetic
Drug tolerance to repeated administration of a drug
Tachyphylaxis
One-half of the drug concentration to be eliminated
Half-life
Drug bound to protein
Protein binding
Effect of drug action on cells
Pharmacodynamics
Drug that blocks a response
Antagonist
Toxic effect as a result of drug dose or therapy
Toxicity
Located on a cell membrane to enhance drug action
Receptor
Drug that produces a response
Agonist
Psychologic benefit from a compound that may not have the chemical structure of a drug effect
Placebo
Causes inactive drug action/response
Protein-bound drug
Free active drug causing a pharmacologic response
Unbound drug
Proceeds directly from intestine to the liver
Hepatic first pass
Breakdown of a drug into smaller particles
Dissolution
Drug absorbed by diffusion
Passive absorption
Drugs that affect various receptors
Nonselective receptors
Time it takes a drug to reach minimum effective concentration
Onset
Occurs when a drug has reached its highest plasma concentration
Peak Action
Length of time a drug has a pharmacologic effect
Duration of action
The margin of safety of a drug
Therapeutic index