Exam 1 Review Questions Flashcards
-ol
Beta 2 agonist
-zoline
Alpha 1 selective agonists
-zosin
Alpha 1 selective antagonists
-high incidence of orthostatic hypotension (limited effect on reflex tachycardia)
doxa-pra-tera
Non-selective alpha blockers
phentolamine (OraVerse) - LA reversal/vasodilation
phenoxybenzamine (Dibenzyline) - Raynaud’s/vasodil.
-lol
beta 2 antagonists
Mixed Alpha/Beta Antagonists
labetolol
carvedilol: hypertensive emergency/cocaine OD
Non-selective beta antagonist
propranolol (high lipid solubility - BBB)
-Migraines, essential tremor, thyrotoxicosis, etc.
sotalol (Betaspace)
Non-selective beta blocker
class 3 K+ channel blocker
Anti-arrythmic
metoprolol
Beta 1 specific antagonist
-Most common prescription for A-Fib
timolol (Timoptic) vs. betaxolol (Kerlone)
timolol is non-selective beta antagonist
betaxolol is beta 1 selective antagonist
Both used for glaucoma patient (ciliary body)
-mab
Monoclonal antibody (seratonin
Fremanezumab
Galcanezumab
Attach to CGRP; migraine treatment
Erenumab
Blocks CGRP receptor; migraine treatment
ergonovine (Ergotrate)
post-partum hemhorrage control
alpha and seratonin stimulation
bromocriptine
Parkinson’s
Dopamime stimulation
ergotamine
migraine treatment
alpha vasoconstriction and seratonin stimulation
sumatriptan (Imititrex)
5-HT1B/D Seratonin agonists
- prevent vasodilation (migraine treatment)
- Seratonin Syndrome (life threatening) is treated with esmolol (a Beta 1 antagonist)
Sympathomimetic Antagonists
acebutolol
penbutalol
pindolol
For epinephrine, which receptors dominate at low doses?
Beta receptors