Exam 1 Review Flashcards

1
Q

Acetic acids NSAIDs - 2

A

Etodolac

Diclofenac

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Celecoxib MAX

A

400mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Qd

A

Every day

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

1 oz = __g

A

30g

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

1 fl oz = __mL

A

30mL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

1 lb = ___kg

A

.45kg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Diclofenac MAX

A

1200mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Albumin has a strong affinity for weak acids. Which drug did we use as an example for high affinity protein binding?

A

Penicillin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Ibuprofen MAX

A

2400-3200mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Sq (sc)

A

Subcutaneous

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

1 kg = ___ lb

A

2.2lb

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

APAP dosing

A

325-650mg q 4-6hr

1000mg q 6-8 hr

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

1 lb = ___g

A

454g

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

4 drugs with established therapeutic ranges

A

Digoxin
Lithium
Phenytoin
Cyclosporin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

C fibers features

A

Unmyelinated
Slow
Dull, aching pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

All opioids we talked about are schedule II - which two arent and what schedule are they?

A

(III) codiene + APAP (tylenol #)

(IV) tramadol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Naproxen dosing

A

500mg stat

250-500mg q 6-8hr

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Naproxen Na MAX

A

1375mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Propionic acid NSAIDs - 4

A

Ibuprofen
Flurbiprofen
Naproxen
Naproxen Na

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Which are the phenanthrene opioids?

A
Codiene
Hydrocodone
Oxycodone
Morphine
Hydromorphone
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

APAP CD

A

1000mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Which LA is best used for dental infections (bc it’s pKa is the most acidic)?

A

Mepivicaine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

ASA analgesic/pyretic dosing

A

325-600mg q 4-6hr

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

1 gram = ___ grain (gr)

A

15.4 grain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

ASA classification

A

Acetylated salicylic acid derivative

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

ASA MAX

A

4000MG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

ASA adult LD

A

10-30gm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

APAP MAX with liver disease

A

2000mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Etodolac MAX

A

1500mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

6 schedule II drugs

A
Morphine
Oxycodone
Hydrocodone
Hydromorphone
Codeiene (alone)
Cocaine HCl
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Selective COX2 inhibitor NSAID - 1

A

Celecoxib

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Diflunisal MAX

A

1500mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

1 L = __ qt

A

1.06qt

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

Flurbiprofen dosing

A

50-100mg BID/QID

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

Naproxen MAX

A

1250-1500mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

1 schedule III drug

A

Tylenol #3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

ASA kid LD

A

4gm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

Ac

A

Before meals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

Po

A

By mouth

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

Etodolac dosing

A

200-400mg q 6-8 hr

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

Qod

A

Every other day

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

Name 2 drugs that undergo the 1st pass effect (if taken orally)

A

Morphine

Nitroglycerine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

A delta fibers features

A

Myelinated
Fast
Sharp pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

APAP MAX

A

3000-4000mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

2 drugs with active metabolites

A

Codeine (morphine)

Benzos

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

Difunisal classification

A

Non acetylated salicylic acid derivative

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

Diflunisal dosing

A

500-1000mg stat

250-500mg q 8-12 hr

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
48
Q

Celecoxib dosing

A

400mg stat

100-200mg BID

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
49
Q

1 tbsp = __cc

A

15cc

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
50
Q

Ibuprofen CD

A

400-800mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
51
Q

ASA antiplatelet dosing

A

81-325mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
52
Q

How many half lives does it take to reach steady state concentration?

A

4-5 t1/2’s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
53
Q

ASA CD

A

1000MG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
54
Q

Diclofenac dosing

A

50mg TID

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
55
Q

Schedule IV class of drugs

A

Benzos

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
56
Q

Qs

A

Sufficient quantity

57
Q

Hs (qhs)

A

@ bedtime

58
Q

Pc

A

After meals

59
Q

1 tbsp = __tsp

A

3 tsp

60
Q

Drug with a toxic metabolite

A

APAP

61
Q

1 tsp = __cc

A

5cc

62
Q

1cc = ___mL

A

1mL

63
Q

Flurbiprofen MAX

A

300mg

64
Q

Sig

A

Directions for use

65
Q

Naproxen Na dosing

A

275-550mg stat, then q 6-8 hr

66
Q

Primary prostaglandin involved in pain

A

PGE2

67
Q

1 gr = __mg

A

60mg

68
Q

Which are the phenylpiperidine opioids?

A

Meperidine (Demerol)

69
Q

Ibuprofen dosing

A

400-800mg q 4-6 hr

70
Q

Which opiods have active metabolites? (4)

A

Codiene
Hydrocodone
Oxycodone
Morphine

71
Q

Which opiods are subject to CYP polymorphism (2D6)? - 3

A

Codiene
Oxycodone
Tramadol

72
Q

Codiene dose forms

A

15-60mg

73
Q

Codiene dosing

A

30-60mg q4-6hr

74
Q

Codiene + APAP dosage forms

A

7.5-60mg codiene

300mg APAP

75
Q

Codiene + APAP dosing

A

30-60mg codiene q4-6hr

<4gm qd

76
Q

Hydrocodone + APAP dosage forms

A

2.5-10mg hydrocodone

325mg APAP

77
Q

Hydrocodone + APAP dosing regimen

A

5-10mg hydrocodone q4-6hr

<4gm qd

78
Q

Hydrocodone + ibuprofen dosage forms

A

5-7.5mg hydrocodone

200mg ibuprofen

79
Q

Hydrocodone + ibuprofen dosing regimen

A

1-2 tabs q4-6hr

80
Q

Oxycodone + APAP dosage forms

A

2.5-10mg oxy

325mg APAP

81
Q

Oxycodone + APAP dosing regimen

A

2.5-10mg oxy q6hr

<4gm qd

82
Q

Oxycodone + ibuprofen dosage forms

A

5mg oxy

400mg ibuprofen

83
Q

Oxycodone + ibuprofen dosing regimen

A

1 tab q6hr

84
Q

Oxycodone + ASA dosage forms

A

5mg oxy

325mg ASA

85
Q

Oxycodone + ASA dosing regimen

A

1 tab q6hr

86
Q

Morphine dosage forms

A

15-60mg

87
Q

Morphine dosing regimen

A

10-30mg q4hr

88
Q

Hydromorphone dosage forms

A

2mg

4mg

89
Q

Hydromorphone dosing regimen

A

2-8mg q3-4hr

90
Q

Meperidine dosage forms

A

50mg

100mg

91
Q

Meperidine dosing regimen

A

50-150mg q2-4hr

92
Q

Most potent opioid

A

Hydromorphone

93
Q

Least potent opioid

A

Codiene

94
Q

Evizo dosage forms

A

2mg (.4mL) prefilled auto injectors IM/SQ into thigh

95
Q

Narcan Nasal spray dosage forms

A

2mg

4mg

96
Q

Evizo dosing regimen

A

2mg q2-3min

97
Q

Narcan nasal spray dosing regimen

A

1 spray q2-3min

98
Q

Narcan injectable dosage forms

A

IV, SQ, IM
.02mg/mL
.4mg/mL
1mg/mL

99
Q

Narcan injectable dosing regimen

A

.4-2mg repeated 12-3min (up to 10mg)

100
Q

Typical duration of max pain intensity

A

2-3 days

101
Q

DOC for mild/moderate pain

A

400-600mg ibuprofen

102
Q

Fetal [drug] = __% of maternal [drug]

A

50-100%

103
Q

Pregnancy antibiotic DOC

A

(B lactam ring)
Penicillins
Cephalosporins

104
Q

Pregnancy antibiotic DOC w PCN allergy

A

Azithromycin (macrolide)

Clindamcin (lincosamide)

105
Q

Pregnancy antifungal DOC

A

Nystatin

Clotrimazole

106
Q

Pregnancy antiviral DOC

A

Penciclovir

107
Q

Pregnancy nonopioid analgesic DOC

A

APAP

108
Q

Pregnancy opioid DOC

A

Oxycodone + APAP

109
Q

Nitrous oxide - fetal [plasma] = ___% of maternal

A

80%

110
Q

Pregnancy LA DOC

A

Lidocaine

Prilocaine

111
Q

Which drug has a black box warning for peds pts?

A

Codeine - metabolize too quickly

112
Q

You can give a kid an adult dose @ ___kg body weight

A

40kg

113
Q

What are the 3 categories of drugs that are the biggest culprits of xerostomia?

A

Strong diuretics
Incontinence meds
Strong anticholinergics

114
Q

Strong anticholinergics are known to cause xerostomia. Which 3 drug classes are included in this?

A

TCAs
Psychotropics
Opioids

115
Q

Strong diuretic - culprit in xerostomia

A

Furosemide (Lasix)

116
Q

Incontinence meds that cause xerostomia (2)

A

Oxybutynin (Ditropan)

Tolterosdine (Detrol)

117
Q

4 psychotropics (strong anticholinergics) that cause xerostomia

A

Quetiapine
Mirtazapine
Risperidone
Olanzapine

118
Q

TCA (strong anticholinergic) causing xerostomia

A

Amitriptyline

119
Q

Max # of LA carps/visit for old ASA II + III pts

A

2-3 carps

120
Q

Biggest risk of NSAID use in elderly pts

A

Ulcers

60% of elderly people can have asymptomatic ulcers

121
Q

Most ADEs caused by LAs in elderly is caused by what?

A

Vessel injection

Use gow gates

122
Q

DOC for elderly anxiolytics?

A

2nd generation benzos - Lorazepam (starting w ½ dose)

NOT VALIUM

123
Q

What is ALWAYS the DOC analgesic for elderly

A

APAP

124
Q

The max daily dose of APAP is 3-4gm/day. What are the 2 conditions in the elderly that you need to adjust the MAX for? How do you adjust it?

A

Hepatic insufficiency
Alcohol abuse
Decrease by 50-75%

125
Q

If an elderly pt can’t take APAP, what are the NSAID options?

A

Ibuprofen

Salsalate

126
Q

What are the 2 opioid options for elderly pts?

A

APAP + codeien #2 or #3

Oxycodone/APAP

127
Q

What are the 6 meds on the Beers list of potentially inappropriate meds for older adults that are often used in dentistry?

A
Diphenhydramine
Long acting NSAIDs
Meperidine
Pentazocine
Long acting benzos
Muscle relaxants
128
Q

List 4 characteristics of drugs commonly involved in ADIs?

A

CYP450 involved
Highly protein bound
Chronic use
Narrow TI

129
Q

6 drugs that have a narrow TI that are commonly involved in ADIs

A
Digoxin
Warfarin
Cyclosporine
Lithium carbonate
Methotrexate
Phenytoin
130
Q

3 highly protein bound drugs that are commonly invovled in ADIs

A

Warfarin
Phenytoin
Sulfonylureas (glybride)

131
Q

What class of drugs is commonly invovled in ADIs due to their tendency to displace other protein bound drugs?

A

NSAIDs

132
Q

Epinephrine has DIs with? 2

A

TCAs

Coke, meth

133
Q

NSAIDs DIs - 4

A

Alcohol
HTN drugs (ACEIs, diuretics, beta blockers)
SSRIs
Low dose ASA

134
Q

NSAIDs or ASA has DI which which drug?

A

Warfarin

135
Q

Tetracyclines have interactions with which 3 drugs?

A

Dairy products
Antacids
Ca + Fe supplements

136
Q

Metronidazole has interactions with which 2 drugs

A

Lithium

Alcohol

137
Q

Amoxicillin has interactions with which drug

A

Warfarin

138
Q

Azithromycin and clarithromycin has interactions with which drug

A

Digoxin

139
Q

Benzos have interactions with which 5 drugs

A
Alcohol
Opioids
Antihistamines
Macrolide antibiotics
Protease inhibitors