Exam 1 - Review

Question 1

The use of computer datases/algorithms to analyze proteins/genes/complete collection of DNAs that comprise an organism (i.e. genome)

Answer 1

Bioinformatics

Question 2

Intersection of healthcare and data acquisition/analysis, bringing together the skills of healthcare and computer sciences in order to improve healthcare.

Answer 2

Medical informatics

Question 3

Division of GenBank, contains sequence data and other information on “single-pass” cDNA sequences from numerous organisms.

Answer 3

dbEST

Question 4

System that automatically partitions GenBank sequences into a non-redundant set of gene-oriented clusters.

Answer 4

UniGene

Question 5

Stores gene expression profiles derived from curated GEO Dataset

Answer 5

Geo profiles

Question 6

Stores original submitter-supplied records (i.e. series, samples, and platforms) as well as curated Datasets

Answer 6

GEO datasets

Question 7

What is GUI?

Answer 7

A graphical representation which allows users to interact with software through graphical icons.

Question 8

What is command line?

Answer 8

Console or text-based representation in which the user types commands to operate software or devices

Question 9

A program that controls the hardware and provides services to other programs (i.e. Linux or Windows)

Answer 9

Operating system

Question 10

A way of specifying operations

Answer 10

Programming language

Question 11

What are some challenges bi data analytics in healthcare face?

Answer 11

Capture, cleaning, storage, security, visualization, updating

Question 12

What is a data silo?

Answer 12

A collection of information in an organization that is isolated from and not accessible by other parts of the organization

Question 13

Field looking to improve disease outcomes by developing smart diagnostics and targeted therapeutics.

Answer 13

Translational genomics

Question 14

Used to determine whether a particular therapy will be useful for a patient.

Answer 14

Clinical genomics

Question 15

What is a transcriptome?

Answer 15

All RNA molecules in one cell or a population of cells

Question 16

Generally describe how RNA-seq is used.

Answer 16

Converts long RNAs into a library of cDNA fragments which are sequenced using high-throughput sequencing and aligned to a reference genome

Question 17

What are the components of a good abstract?

Answer 17

Informative title, explains project and why it is important, describes the known an unknown (i.e. how will the unknown be addressed), explains tools used, describes results