exam 1 quiz 1

Question 1

1st gen antipsychotics aka and 2nd gen antipsychotics aka

Answer 1

1st gen = conventional, 2nd gen = atypical

Question 2

5 things antipsychotic drugs can be used for that isn’t mental health

Answer 2

antiemetics, Tourette’s syndrome, huntington’s chorea, delirium, migraine headache

Question 3

is haloperidol 1st or 2nd gen

Answer 3

1st

Question 4

is chlorpromazine 1st or 2nd gen

Answer 4

1st

Question 5

how do 1st gen antipsychotics work?

Answer 5

block dopamine-2 (D2) receptors, limit activity of dopamine

Question 6

MOA of 2nd gen antipsychotics?

Answer 6

block dopamine and serotonin

Question 7

alogia

Answer 7

poverty of thought and speech

Question 8

avolition

Answer 8

loss of motivation

Question 9

anhedonia

Answer 9

inability to experience pleasure or joy

Question 10

delusions

Answer 10

false, fixed beliefs that cannot be corrected by reasoning

Question 11

1st gen antipsychs primarily target what kind of symptoms?

Answer 11

positive

Question 12

2nd gen antipsychs target which kinds of symptoms?

Answer 12

positive and negative, too

Question 13

antidote for anticholinergic toxicity?

Answer 13

physostigmine

Question 14

list three 2nd gen antipsychotics

Answer 14

risperidone, olanzapine, clozapine

Question 15

risk w/ clozapine?

Answer 15

agranulocytosis

Question 16

mandatory lab with clozapine?

Answer 16

weekly WBC counts for first 6 months, then frequent monitoring

Question 17

neutropenia

Answer 17

WBC below 1500

Question 18

common organ impairment w/ antipsychotics?

Answer 18

liver - frequent liver function tests

Question 19

anticholinergic toxicity s/s?

Answer 19

hyperthermia, hot/dry/red skin, reduced bowel sounds, paralytic ileus, agitation, delirium, fluctuating VS, tachycardia, mydriasis, mental status changes, worsening psych symptoms

Question 20

antipsych with potential to increase QT?

Answer 20

rispiridone

Question 21

NMS?

Answer 21

neuroleptic malignant syndrome

Question 22

s/s of NMS?

Answer 22

reduced consciousness, muscular rgidity, autonomic dysfunction (hyperpyrexia, labile hypertension, tachycardia, tachypnea, diaphoresis, drooling)