exam 1 psychopharmacology

Question 1

study of the use of psychotropics

Answer 1

psychopharmacolgy

Question 2

study of what the body does to the drug

Answer 2

Pharmacokinetics

Question 3

The study of what drugs do to the body is called

Answer 3

Pharmacodynamics

Question 4

absorption, distribution, metabolism, excretion is part of what

Answer 4

pharmacokinetics

Question 5

these things increase the serum level of other drugs

Answer 5

enzyme enhancers

Question 6

these things decrease the serum level of other drugs

Answer 6

enzyme inducers

Question 7

part of the brain that regulates powerful emotions

Answer 7

amygdala

Question 8

relay station for sensory info

Answer 8

thalamus

Question 9

essential for maintaining homeostasis of basic needs

Answer 9

hypothalamus

Question 10

which lobe is involved in executive functioning

Answer 10

frontal lobe

Question 11

made from tryptophan and made in the Raphe nuc

Answer 11

serotonin

Question 12

Made in the Locus Ceruleus and involved in the noradrenergic pathways

Answer 12

norepinephrine

Question 13

90% of serotonin receptors are found in the:

Answer 13

GI tract

Question 14

four major brain pathways

Answer 14

mesolimbic, mesocortical, nigrostriatal, tuberoinfundibulum

Question 15

produced in the ventral tegmental area (VTA) and acts on the 4 major pathways

Answer 15

dopamine

Question 16

dopamine inhibits prolactin in what pathway

Answer 16

tuberoinfundibulum

Question 17

increased dopamine in this pathway causes + symptoms

Answer 17

mesocortical

Question 18

decreased dopamine in this pathway causes motor symptoms

Answer 18

nigrostriatal

Question 19

main inhibitory neurotrans that creates calm

Answer 19

GABA

Question 20

main excitatory neurotrans

Answer 20

glutamate

Question 21

most drugs are broken down in the

Answer 21

liver

Question 22

what electrolyte is commomly affected by psychotrophic meds

Answer 22

sodium (hyponatremia)

Question 23

what is the therapeutic index

Answer 23

ratio that compares the toxic dose versus the effective dose

Question 24

chemical that binds to a receptor to produce an effect

Answer 24

agonist

Question 25

chemical that binds to a receptor but doesnt fully activate it

Answer 25

partial agonist

Question 26

chemical that binds and blocks the receptor

Answer 26

antagonist

Question 27

agent binds to the same receptor as an agonist but produces the OPPOSITE reaction

Answer 27

inverse agent

Question 28

undesired but foreseen reaction

Answer 28

side effect

Question 29

what is the mesolimbic pathway associated with

Answer 29

positive symptoms of schizophrenia, SGAs reduce dopamine activity here, which helps alleviate hallucinations.

Question 30

what is the mesocortical pathway associated with

Answer 30

related to negative symptoms, SGAs have less of a dopamine-blocking effect here, which helps preserve or even enhance dopamine transmission in this pathway decreasing anhedonia

Question 31

what is the Nigrostriatal pathway associated with

Answer 31

Movement and balance

Question 32

what is the tuberoinfundibular pathway associated with

Answer 32

dopaminerigc pathway associated with prolactin secretion. Antipsychotics block dopamine receptors here and increase the production of prolactin