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Virology > Exam 1 - Practice Quiz > Flashcards

Exam 1 - Practice Quiz Flashcards

1
Q

Swine influenza

A

Shope

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2
Q

Rabies vaccine, beer, father of microbiology

A

Louis Pasteur

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3
Q

Genome project

A

Craig Venter

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4
Q

1st virus discovered, Foot and mouth disease, postulates

A

Loffler, Frosch, Koch

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5
Q

Concept of possible vaccination, small pox in people

A

Edward Jenner

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6
Q

Globally eradicated

A

Small pox (1980), Rinderpest (2011)

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7
Q

Human measles/canine distemper

A

Viral family relationship

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8
Q

Respiratory vs. enteric vs. congenital

A

Epidemiological grouping of viruses

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9
Q

Cell receptor complementarity

A

Characteristics of host cell

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10
Q

Capsid, intracellular replication, DNA or RNA

A

Basic characteristics/structures of viruses

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11
Q

Feline panleukopenia/canine parvovirus

A

Viral family relationship

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12
Q

Cytopathic (cell death, giant cells/syncytia, inclusions), oncogenic formation

A

Cellular changes due to viral infection

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13
Q

Laboratory measurements of viral infectivity

A

TCID50 and plaque assay

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14
Q

Pathogenicity

A

Ability of virus to cause disease

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15
Q

Immune defenses, susceptibility, age, genetics

A

Host influence on infection outcome

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16
Q

Papilloma wart in skin

A

Localized infection

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17
Q

Numbers of particles, virulence, ability to damage cells, tropism

A

Virus influence on infection outcome

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18
Q

Respiratory, neurological, gastrointestinal signs in CDV

A

Systemic infection

19
Q

Latent-recurrent infection

A

Herpesviruses

20
Q

Acute self-limiting infection

A

Influenza viruses

21
Q

Acute infection with late complication

A

Canine distemper virus

22
Q

Slow infection ending in disease episode

A

Prion diseases

23
Q

Chronic infections

24
Q

Chronic infection with late disease

25
Q

Staining of tissue sections

A

Detect virus - immunohistochemistry, immunofluorescence, in-situ hybridization

26
Q

Snap tests

A

Either detect virus or detect antibodies - ELISA

27
Q

Antibody titer

A

Detect antibodies - ELISA, virus neutralization, hemagglutination inhibition

28
Q

Cell culture of nasal swabs

A

Detect virus - virus isolation

29
Q

Visualize viral particles

A

Detect virus - electron microscopy

30
Q

Identification of RNA or DNA

A

Detect viral genome (antigen) - PCR, gene sequencing

31
Q

Egg inoculation

A

Detect virus - virus isolation (used for Influenza)

32
Q

For diagnostic purposes, important to try to collect samples when peak viremia occurs. This optimized chances of detecting virus in collected specimens. When does peak viremia occur?

A

When fever peaks (pyrexia)

33
Q

Still has abilty to infect cells, may still be virulent in some species

A

Modified live (attenuated)

34
Q

Use ELISA to detect antibodies to wild type but not marker vaccine strain

A

DIVA - differentiation of infected from vaccinated animals

35
Q

Instructs cell to make a specific antigenic protein

A

mRNA vaccine

36
Q

Use recombinant virus vector from unrelated species

A

Canarypox for ferret canine distemper (CDV) vaccine

37
Q

Bedding, grooming equipement

A

Indirect transmission

38
Q

Point mutation that allows infection of a new host species

A

Antigenic drift

39
Q

Point mutation that allows immune escape

A

Antigenic drift

40
Q

Prolonged period of viral shedding

A

Persistent infection

41
Q

Genetic reassortment between viruses results in major antigenic change

A

Antigenic shift

42
Q

Dead-end host

A

Infected, but level of viremia not sufficient for transmission to occur

43
Q

Being born

A

Congenital transmission

44
Q

Rubbing, licking, intercourse

A

Direct contact transmission

Virology (2 decks)

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