Exam 1: Patho (Anemias)

Question 1

Pernicious anemia

Answer 1

(Macrocytic-normochromic)

Lack of vitamin B leads to altered DNA synthesis

Question 2

Folate deficiency

Answer 2

(Macrocytic-normochromic; Decreased RBC production)

Lack of folate leads to premature cell death

Question 3

Iron deficiency

Answer 3

(Microcytic-hpochromic; Decreased RBC production)

Lack of iron leads to lack of hemoglobin

Question 4

Thalassemia

Answer 4

(Microcytic-hypochromic; Inherited disorders)

Congenital - impaired synthesis of hemoglobin chain

Question 5

Sickle cell anemia

Answer 5

(Inherited disorders; Normocytic-normochromic)

Congenital-abnormal hemoglobin molecule

Question 6

Post hemorrhage

Answer 6

(Normocytic-Normochromic; Extrinsic RBC destruction or loss)

Blood loss leads to insufficient RBC

Question 7

Anemia of chronic Disease

Answer 7

(Normocytic-Normochromic; Decreased RBC production)

Chronic infection, inflammation, malignancy leads to increased demand or suppression

Question 8

hemolytic disease of the newborn

Answer 8

(Extrinsic RBC destruction or loss)

maternal antibodies cause destruction of fetal cells

Question 9

Acute blood loss

Answer 9

(Extrinsic RBC destruction or loss)

blood loss leads to insufficient RBC

Question 10

Aplastic anemia

Answer 10

(Normocytic-Normochromic; Decreased RBC Production)

Bone marrow suppression leads to decreased production (Toxic, radiant, immune injury)