Exam 1: Mentimeter Questions Flashcards

1
Q

Which of the following is not one of the three major lines of defense: adaptive immunity, physical barriers, autoimmunity, innate immunity

A

Autoimmunity

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2
Q

Cardinal signs of inflammation

A

Heat, pain, redness, swelling

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3
Q

What type of pathogen is free-living but lacks a membrane bound nucleus

A

Bacteria

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4
Q

Immune privileged sites

A

Brain & eyes

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5
Q

How does fluid from an infected site drain into the lymphatic system

A

Through blind ended lymphatic vessels

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6
Q

What kind of molecules do TCR and BCR recognize

A

BCR recognizes macromolecules and TCR recognizes peptides

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7
Q

How do lymphpcytes exit the lymph node

A

Efferent lymphatics

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8
Q

Defensins are amphipathic. What does this mean

A

Contain both hydrophilic and hydrophobic regions

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9
Q

Which complement activation pathway produces anaphyltoxins

A

All: alternative, lectin, and classical

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10
Q

Which of these is associated with the classical complement pathway: mannose binding lectin (MBL), spontaneous hydrolysis, antibodies, Factor B & D

A

Antibodies

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11
Q

Which is NOT a C3 convertase: iC3Bb, C3bC4b, C3bBb, C4bC2a

A

C3bC4b

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12
Q

Which pathogen associated molecular pattern (PAMP) is recognized by TLR5

A

Flagellin

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13
Q

Which innate cell is not a phagocyte

A

NK cell

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14
Q

Which neutrophil receptor initiates “rolling adhesion” from the blood

A

L-selectin

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15
Q

The term for when a cytokine acts back on the same cell that produced it

A

Autocrine signaling

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16
Q

Which enzyme is responsible for somatic recombination of VDJ segments of the B cell receptor

A

RAG1/2

17
Q

Where are N nucleotides found

A

In the center, between the P nucleotides (often symbolized as darkly colored)

18
Q

Which term describes the process of changing from an IgM to IgG antibody

A

Isotype switching

19
Q

Monoclonal antibodies are generated by the fusion of ___

A

B cells and myeloma cells