Exam 1: Mentimeter Questions Flashcards
Which of the following is not one of the three major lines of defense: adaptive immunity, physical barriers, autoimmunity, innate immunity
Autoimmunity
Cardinal signs of inflammation
Heat, pain, redness, swelling
What type of pathogen is free-living but lacks a membrane bound nucleus
Bacteria
Immune privileged sites
Brain & eyes
How does fluid from an infected site drain into the lymphatic system
Through blind ended lymphatic vessels
What kind of molecules do TCR and BCR recognize
BCR recognizes macromolecules and TCR recognizes peptides
How do lymphpcytes exit the lymph node
Efferent lymphatics
Defensins are amphipathic. What does this mean
Contain both hydrophilic and hydrophobic regions
Which complement activation pathway produces anaphyltoxins
All: alternative, lectin, and classical
Which of these is associated with the classical complement pathway: mannose binding lectin (MBL), spontaneous hydrolysis, antibodies, Factor B & D
Antibodies
Which is NOT a C3 convertase: iC3Bb, C3bC4b, C3bBb, C4bC2a
C3bC4b
Which pathogen associated molecular pattern (PAMP) is recognized by TLR5
Flagellin
Which innate cell is not a phagocyte
NK cell
Which neutrophil receptor initiates “rolling adhesion” from the blood
L-selectin
The term for when a cytokine acts back on the same cell that produced it
Autocrine signaling
Which enzyme is responsible for somatic recombination of VDJ segments of the B cell receptor
RAG1/2
Where are N nucleotides found
In the center, between the P nucleotides (often symbolized as darkly colored)
Which term describes the process of changing from an IgM to IgG antibody
Isotype switching
Monoclonal antibodies are generated by the fusion of ___
B cells and myeloma cells
