Exam 1 Meds (Category, Class, SE/AE, Nursing Consideration/Intervention)) Flashcards
amoxicillin (Amoxil)
cell wall synthesis inhibitor
broad spectrum penicillin antibiotic
SE: allergic reaction
Nrsg: Assess for allergy to penicillin or cephalosporin/obtain C&S before abx therapy
ceftriaxone (Rocephin)
cell wall synthesis inhibitor
3rd gen cephalosporin antibiotic (respiratory infection)
SE: nephrotoxicity, pseudomonas colitis, anaphylaxis (contraindicated for PCN), superinfection of oral or vaginal candidiasis
vancomycin
cell wall synthesis inhibitor
glycopeptide antibiotic (for MRSA, pseudomembranous colitis caused by C. diff)
SE: red man syndrome (occurs when IV is administered too rapidly), ototoxicity, nephrotoxicity
Nrsg: administer over 1-2 hrs IV
azithromycin (Zithromax)
protein synthesis inhibitor
macrolide antibiotic
SE: photosensitivity, nephrotoxicity, hepatotoxicity
Nrsg: penicillin substitute
doxycycline (tetracycline)
protein synthesis inhibitor
tetracycline antibiotic (acne, H. Pylori, STIs)
SE: discoloration of teeth; CNS toxicity (nightmares)
Nrsg: NO antacid; can take have food and milk products (2hr before or after); do NOT give to children <8 y/o; pregnancy cat D
tetracycline (Sumycin)
protein synthesis inhibitor
tetracycline antibiotic (acne, H. Pylori, STIs)
SE: discoloration of teeth; CNS toxicity (nightmares)
Nrsg: NO antacid; NO food or milk; do NOT give to children <8 y/o; pregnancy cat D
gentamicin (Geramycin)
protein synthesis inhibitor
aminoglycoside antibiotic (serious systemic infections)
SE: ototoxicity and nephrotoxicity
Nrsg: narrow TI so check P&T; check for hearing loss and renal function
ciprofloxacin (Cipro)
DNA synthesis Inhibitor
fluoroquinolone (bacteriostatic)
SE: tendon rupture; tendonitis; serious heart dysrhythmias
Nrsg: NO antacids; monitor HR, increase fluids; monitor blood glucose
levofloxacin (Levoquin)
DNA synthesis Inhibitor
fluoroquinolone (bacteriostatic)
SE: tendon rupture; tendonitis; serious heart dysrhythmias
Nrsg: NO antacids; increases effect of oral hypoglycemic and caffeine, monitor HR, increase fluids; monitor blood glucose
trimethoprim/sulfamethoxazole (Bactrim)
Metabolism inhibitor
sulfonamide (bacteriostatic) (for UTI)
SE: crystalluria, photosensitivity
Nrsg: increase fluids b/c crystallization my cause kidney stones or kidney failure
isoniazid (INH)
1st line TB drug (inhibit cell wall synthesis)
SE: peripheral neuropathy; liver toxicity
Nrsg: vitamin B6; eat 1-2 hrs before or after; NO alcohol; no OTC drugs
rifampin
1st line TB drug (inhibits enzymes needed for protein synthesis)
SE: reddish-orange secretions; liver toxicity
Nrsg: no alcohol; do NOT take with food; no OTC drugs
ethambutol
1st line TB drug (inhibits cell wall synthesis)
SE: optic neuritis; increase uric acid; liver toxicity
Nrsg: no alcohol; no OTC drugs
amphotericin B (Fungizone)
antifungal
polyene (serious systemic fungal infection)
SE: “shake and bake” within 1-3 hrs (fever, chills, HA, tachycardia, hypotension); electrolyte imbalance (hypokalemia), nephrotoxicity
Nrsg: pretreat 30-60min before with acetaminophen, diphenhydramine, hydrocortisone; monitor BUN and creat; watch for OTC b/c of drug interactions
nystatin (Mycostatin)
antifungal
polyene (serious candida infection)
“swish and swallow”
SE: electrolyte imbalance (hypokalemia), nephrotoxicity
Nrsg: monitor BUN and creat ; watch for OTC b/c of drug interactions