Exam 1 Material Flashcards
What are the four basic tissues of the human?
epithelial, muscle, neural & connective tissue
What is the function of each type of bone cell?
osteoblast - form bone
osteocyte - maintain or nurture bone
osteoclast - remodel bone
What are the bone cells embedded in?
an amorphous matrix consisting of ground substance, protein fibers and various minerals
What is the primary constituent of the ground substance?
glycosaminoglycans
What types of glycosaminoglycans predominate in bone?
chondroitin sulfates, keratin sulfates & hyaluronic acid
What is the principle type of protein fiber in bone?
collagen type I
What are the primary constituents of the bone mineral?
calcium, phosphate, citrate & carbonate ions
What is the most frequently described deposit in bone?
hydroxyapatite
Bone is also the repository for what additional ions?
sodium, magnesium, fluoride, lead, strontium & radium
What is Wolff’s Law as it pertains to bone?
living tissue will respond to stressors such as anxiety, tension or pressure; bone is formed or absorbed in response to these same stressors
What three responses of “living” bone were stressed in class?
it has the ability to heal, to remodel under stressor such as anxiety, tension nor pressure and to age
Bone is the embryological derivative of which specific connective tissues?
mesenchyme and/or cartilage
What is the name given to the pattern of ossification in mesenchyme?
intramembranous ossification
What is the timing for the appearance of intramembranous ossification?
from the second to third month in utero
What part of the axial skeleton is primarily formed by intramembranous ossification?
the skull
What is the name given to the pattern of ossification in cartilage?
endochondral ossification
Wha tis the timing for the appearance of ossification in cartilage?
from the second to fifth month in utero
Which skull bones are ossified by both endochondral and intramembranous ossification?
the mandible, sphenoid, temporal & occipital bones
Which bone of the appendicular skeleton is formed by both endochondral and intramembranous ossification?
the clavicle
Wha tare the names given to the venters of ossification based on time of appearance?
primary centers of ossification appear before birth
secondary centers of ossification appear after birth
Mature bone is described as being composed of what areas based on bone density?
cortical or compact bone and spongy, cancellous or trabecular bone
What is the name given to the bone below an articulating surface?
subchondral bone
What is the name of the outer fibro-cellular covering of a bone?
the periosteum
What is the name given to the fibro-cellular lining of bone?
the endosteum
What are the primary sources of variation observed in bone?
sexual dimorphism (gender variation), ontogenetic variation (growth or age variation), geographic or population-based variation (ethnic variation) and idiosyncratic variation (individual variation)
Differences in the number of morphology of vertebrae within the population based on male and female variation is identified as which type of variation?
sexual dimorphism or gender variation
Differences in the number or morphology of vertebrae within the population based on age or developmental variation is identified as which type of variation?
ontogenetic variation
Differences in the number or morphology of vertebrae within the population based on ethnicity or locational variation is identified as which type of variation?
geographic variation or population based variation
What are the six more commonly used classifications of normal bone?
long bones, short bones, flat bones, irregular bones, paranasal sinus or pneumatic bones and sesamoid bones
Which classifications of bone are characteristic of the appendicular skeleton?
long bones, short bones and sesamoid bones
What is the characteristic feature of a long bone?
it is longer than it is across (length greater than breadth)
What are the names given to the parts of a long bone?
the diaphysis (shaft) and typically two epiphyses (extremities)
What is the primary characteristic of short bones?
they are essentially cuboidal
What are examples of short bones?
most of the bones of the carpus and tarsus
What is the characteristic of sesamoid bone?
the bone develops within a tendon
What are consistent examples of sesamoid bones?
patella and pisiform
Which classification of bone are characteristic of the axial skeleton?
flat bones, irregular bones and paranasal sinus or pneumatic bones
What are flat bones?
a thin layer of spongy bone is sandwiched between two layers of compact bone
What are examples of flat bones?
the parietal bone and sternum
What is the name given to the spongy bone of the skull?
diploe
What is characteristic of irregular bone?
numerous projections or irregular outlines
What are examples of irregular bone?
the vertebrae and innominate bones
What is characteristic of pneumatic bone?
air spaces within the bone
What are examples of pneumatic bone?
frontal, ethmoid, maxilla, sphenoid & temporal
What bones contain paranasal sinuses?
frontal, ethmoid, maxilla & sphenoid
What are the classifications given to abnormal bone stressed in Spinal Anatomy?
accessory and heterotopic bone
What is the name given to bone formed from existing bone?
accessory bone
What are examples of accessory bone?
para-articular processes and bony spurs of vertebrae
What is the name given to bone formed in a non-bone location?
heterotopic bone
What are examples of heterotopic bone?
calcific deposits in the pineal gland, heart, and ligaments
What are the four basic surface feature categories?
elevations, depressions, tunnels or passageways & facets
When do the surface features of a bone become prominent?
during and after puberty
What are the types of osseous elevations?
linear, rounded and sharp
What are the types of osseous linear elevation?
the line, ridge and crest
What are the types of rounded osseous elevation?
tubercle, protuberance, trochanter, tuber or tuberosity and malleolus
What are the categories of sharp osseous elevations?
spine and process
What are the categories of osseous depressions?
linear and rounded depressions
What are the categories of osseous linear depressions?
notch or incisor, groove, and sulcus
What are the categories of rounded osseous depressions?
fovea and fossa
What are the names given to openings on the surface of bone?
ostium or orifice and hiatus
What is the definition of an osseous ostium?
a round or oval opening on the surface of bone
What is the definition of an osseous hiatus?
an irregular opening on the surface of bone
What are themes given to osseous ostia which completely penetrate bone?
foramen or canal
What is the name given to to an ostium which does not completely penetrate through a region of bone but appears as a blind-ended passageway?
meatus
What are the categories of osseous facets?
flat facets and rounded facets
What are the categories of rounded osseous facets?
articular heads and articular condyles
How many bones form the typical adult skeleton?
206 bones
What are the subdivisions of the skeleton?
the axial skeleton and appendicular skeleton
How many bones form the typical adult appendicular skeleton?
126 bones
How many bones form the typical adult axial skeleton?
80 bones
What bones form the axial skeleton?
the skull, hyoid, vertebral column, sternum and ribs
What is the total number of bones forming the typical adult skull?
28 bones
What is the name given to the adult skull minus the mandible?
the cranium
What are the names given to the top of the adult skull?
the calvaria or calva
What are the categories of bone forming the typical adult skull?
the neurocranium, the facial skeleton (splanchnocranium or visceral cranium) and the auditory ossicles
What is the neurocranium?
the bones that support or protect the brain
How many bones form the typical adult neurocranium?
8 bones
What bones form the neurocranium of the typical adult skull?
the frontal, parietal, temporal, occipital, sphenoid and ethmoid
How many bones form the facial skeleton (splanchnocranium or visceral skeleton)?
14 bones
What is the facial skeleton (splanchnocranium or visceral cranium)?
the bones that support the face or front of the head
What bones form the facial skeleton?
mandible, vomer, nasal, maxilla, lacrimal, inferior nasal concha, palatine and zygomatic
By strict definition, what is the splanchnocranium?
the bones that support the face minus the mandible
What bones form the splanchnocranium?
vomer, nasal, maxilla, lacrimal, inferior nasal concha, palatine and zygomatic
How many bones comprise the typical adult auditory ossicles?
6 bones
How many bones are present in the adult hyoid?
1 bone
What is the number of bones comprising each region of the typical adult spinal column or vertebral column?
7 cervical, 12 thoracic, and 5 lumbar vertebrae, 1 sacrum and 1 coccyx
What is the name given to the presacral region of the typical adult vertebral column or spinal column?
the spine
Wha tis the total number of bones forming the typical adult spine?
24 bones
What is the definition of spine as it pertains to the vertebral column?
the pre-sacral region of the vertebral column or spinal column
How many bones are present in the typical adult sternum
1 bone
What regions are present along the typical adult sternum?
the manubrium stern, the corpus stern and the xiphoid process
How many ribs are present in the typical adult skeleton?
12 pair or 24 ribs
What is the number of vertebrae in a typical adolescent?
33 segments
What is the number of vertebrae in a typical adult?
26 segments
What constitutes the spine?
the 24 presacral segments; the cervical, thoracic and lumbar vertebrae
How many segments unite to form the typical sacrum?
5 segments
How many segments unite to form the typical coccyx?
4 segments
What does the term “cervical” refer to?
the region of the neck
What is the typical number o segments in the cervical region?
7 segments
What does the term “thoracic” refer to?
breast plate or chest; it referred to the armor bearing region of the torso
What other term is often used to identify the vertebral segments of the chest?
the dorsal segments; the dorsals
What is the typical number of segments in the dorsal or thoracic region?
12 segments
What does the term “lumbar” refer to?
the loin; the region between the rib and the hip
What is the typical number of segments in the lumbar region?
5 segments
What does the term “sacrum” refer to?
the holy bones or holy region
What does the term “coccyx” refer to?
a cuckoo birds’ bill or cuckoo bird’s beak
Which region of the spine is more stable in terms of the number of segments/vertebrae?
the cervical region
What is the length of a typical male spinal column?
about 70 centimeters or 28 inches
What is the length of a typical female spinal column?
about 60 centimeters or 25 inches
What is the difference in length between a typical male and typical female spinal column?
about 3 inches
What is the length of the male cervical region ?
about 12 centimeters or 5 inches
What is the length of the male thoracic region?
about 28 centimeters or 11 inches
What is the length of the male lumbar region?
about 18 centimeters or 7 inches
What is the length of the male sacrum?
about 12 centimeters or 5 inches
Based on the numbers for individual regions of the vertebral column, what is the length of the male spine?
about 58 centimeters or 23 inches
How does the vertebral column participate in protection of neural tissues?
the spinal cord and beginning PNS are located within the vertebral segments
How does the vertebral column participate in protection of the viscera?
ribs are attached to vertebrae to form the thorax thus protecting the heart and lungs
What parts of the body are supported by the vertebral column?
the head, upper extremities, ribs, viscera, and pelvis
How does the vertebral column participate in skeletal formation?
ribs are formed from the costal process of the embryonic vertebral template
What levels of the vertebral column specifically accommodate weigh-baring transfer?
S1-S3 at the auricular surface
Distinguish between motion and locomotion.
motion is movement without travel; locomotion is movement to a new site or location
What is specifically responsible for shape and position of the human frame?
comparative anterior vs posterior height of the vertebral body and comparative anterior vs posterior height of the intervertebral disc
How does the vertebral column accommodate transmission?
the peripheral nerve communicates with the central nerve system via the intervertebral foramen
What organ(s) is (are) specifically associated with the horizontal axis of the skull?
the eye and the vestibular apparatus of the inner ear
How is the vertebral column involved ins stabilization of visceral function?
integrity of the spinal column enhances appropriate nerve system control of viscera
When does gastrulation occur or a 3-layered embryo form?
third week in utero
What are the 3 layers of the embryo called?
ectoderm, mesoderm, endoderm
Invagination of the ectoderm along the primitive streak gives rise to what embryonic structure?
notochord
What is the name given to the mesoderm that will give rise to the vertebral column?
paraxial mesoderm
What does paraxial mesoderm give rise to that will form he vertebral column?
somites
Name the areas of cellular differentiation formed within the somite.
sclerotome, myotome and dermatome
What part of the somite will give rise to the vertebral column?
sclerotome
List, in order, the names of the successive vertebral columns formed during development?
membranous, cartilaginous, skeletal or osseous
Migration of sclerotomes to surround the notochord forms what developmental feature?
the perichordal blastema
The perichordal blastema gives rise to what processes?
neural processes and costal processes
What is the name of the artery located between adjacent perichordal blastemae?
intersegmental artery
Cell proliferation within the perichordal blastema will results in what features?
a loose cranial sclerotomite and a dense caudal sclerotomite
What forms between the sclerotomites of a perichordal blastema?
the intrasclerotomal fissure (fissure of von Ebner)
The intrasclerotomal fissure (fissure of von Ebner) gives rise to what developmental feature?
the perichordal disc
The perichordal disc in the presumptive location of what adult feature?
the intervertebral disc
What is the earliest embryonic feature that will identify the position often adult intervertebral disc?
the intrasclerotomal fissure (fissure of von Ebner)
Th union of a dense caudal sclerotomite and a loose cranial sclerotomite from adjacent perichordal blastemae gives rise to what feature?
the vertebral blastema
What vessel will be identified adjacent to the vertebral blastema?
the segmental artery
When will cartilage first form in the membranous vertebral blastema?
beginning in the 6th embryonic week
What is the name given to the replacement of mesoderm by cartilage?
chondrification
Chondrification is the first identified in which region of the embryonic vertebral column?
the cervical region
What is the names given to the centers of chondrification withi the vertebral blastema?
centrum center, neural arch center, transverse process center
How many centers of chondrification typically appear in the vertebral blastema?
Six…2 for the centrum, 2 for the neural arch, 2 for each transverse process
What is the earliest time that centers of ossification appear in the cartilaginous vertebra?
During the 7th embryonic week
Ossification begins in which region of the embryonic vertebral column?
The lower cervical-upper thoracic region
What is the name given to the centers of ossification based on time of appearance?
Primary centers appear in utero, secondary centers appear after birth
What is the ration of primary to secondary centers of ossification for a typical vertebra?
3 primary centers: 5 secondary centers
What are the names of the primary centers of ossification for a typical vertebra?
Centrum centers and neural arch centers
How many primary centers of ossification appear in the typical vertebra?
Three…1 for centrum, 2 for neural arches
What is te classification of the joint forming between primary centers of ossification?
Cartilage syndchondrosis/amphiarthrosis synchondrosis
What are the names of the synchondroses forming between primary centers of ossification in the typical vertebra?
Neurocentral synchondrosis and neural arch synchondrosis
What are the names of the five secondary centers of ossification for a typical vertebra?
Tip of the transverse process, tip of the spinous process, epiphyseal plate centers
How many secondary centers of ossification appear in the typical vertebra?
Five… 1 for the tip of each transverse process, 1 for the tip of the spinous process, 1 for each epiphyseal plate
Where are the names of the synchondroses forming between secondary centers of ossification and the rest of the typical vertebra?
Tip of the transverse process synchondrosis, tip of the spinous process synchondrosis, and epiphyseal ring synchondrosis
What is the range of appearance for secondary centers of ossification of a typical vertebra?
During puberty, typically ages 11-16 years old
What are the three basic osseous parts of a vertebra?
The vertebral body, vertebral arch, and the apophyseal regions
What is formed by the vertebral body and vertebral arch?
The vertebral foramen
What is the general shape of the vertebral body at each region of the spine?
Cervical - rectangular; thoracic - triangular; lumbar - reniform
What is the name given to the compact bone at the superior and inferior surfaces of the vertebral body?
Superior epiphyseal rim, inferior epiphyseal rim
What is the name given to the cartilage found at te superior and inferior surface of a developing vertebral body?
Superior epiphyseal plate, inferior epiphyseal plate
What are the names of the openings found around the margins of the vertebral body?
Nutrient foramina or vascular foramina
What large opening is usually observe dat the back of the vertebral body?
The basivertebral venous foramen
What is the name of the vessel entering the nutrient or vascular foramen?
Osseous artery
What is the name given to the large vessel exiting the back of the vertebral body?
The basivertebral vein
What is the semicircular region of bone attached to the back of the vertebral body called?
The vertebral arch
What is the name given to the anterior part of the vertebral arch?
The pedicle
What is the name given to the posterior part of the vertebral arch?
The lamina
What is the name given to the intermediate part of the vertebral arch where the transverse process and articular processes attach?
The lamina-pedicle junction
What is the name of the feature at the upper and lower surfaces of the pedicle?
The superior vertebral notch or superior vertebral incisure; th inferior vertebral notch or inferior vertebral incisure
What is the generic orientation of the pedicle at each region of the spine?
Cervical - posteriolateral
Thoracic - posterior, slight lateral
Lumbar - posterior
All lamina are oriented in what direction?
Posterior and median
What is the name given to the overlap of laminate seen on X-ray?
Shingling
What ligament will attach to the lamina?
The ligamentum flavum
What is the name given to abnormal bone the attachment site of the ligamentum flavum?
Para-articular process
What classification of bone will para-articular processes represent?
Accessory bone
What is the name given to the lamina - pedicle junction at each region of the spine?
Cervical - articular pillar; thoracic and lumbar - pars interarticularis
What is the name given to the junction of the vertebral arch - spinous process on lateral x-ray?
The spinolaminar junction
What is the name given to the tubular bone growth regions of the vertebral arch?
Apophyseal regions
What names may be given to each apophyseal of the spine?
The transverse apophyseal or transverse process; articular apophyseal or articular process; spinous apophysis or spinous process