Exam 1 - Lecture 1 Flashcards
renal clearance of stuff from kidney is
volume of plasma cleared over time
CH2O is what?
Clearance of free water or free water clearance, which is volume of water cleared from body per unit of time.
Our free water clearance is _____ when we have alot of ADH
low
Our free water clearance is ____ when we have few ADH
high
How do we calculate the MAP?
Diastolic pressure PLUS 1/3rd of the difference between systolic and diastolic pressure.
e.g.: 80 + ((120 - 80)/3) = 93
Highest resistance blood vessels in circulation are
arterioles
Upstream of arterioles, pressure is _____. Downstream, pressure is
High; low
The blood pressure in the venules is
10 mmHg
What is the pressure in the right atrium
0 mmHg, when healthy. If they are sick, it’ll be higher.
Delta P of systemic circulation is what?
100 mmHg.
100 at the aorta, 0 at the end (right atrium)
Pulmonary arterial pressure MAP is
16 mmHg
What is the MAP referred to in pulmonary artery?
PAP, or mPAP (mean)
Normal systolic and diastolic pressure in pulmonary artery is
25/8
What is the end of the pulmonary circuit?
Left atrium
Pressure of the left atrium
2 mmHg
Delta P of entire pulmonary circuit is
16 - 2 = 14 mmHg
(16 in the PA, 2 in the left atrium.)
PP means
pulse pressure
What is pulse pressure
difference between systolic and diastolic pressure
120/80 = PP of 40
Where is pulse pressure highest?
Large arteries
Why is there a widening of the pulse pressure in the large arteries compared to the aorta?
the walls are more stiff, whereas the aorta is more stretchy.
If the walls are stiff, there will be a _____ pulse pressure. If they are stretchy, there will be a _____ pulse pressure.
Higher; lower
If a vessel wall had zero stretch to it, what does this do during systole and diastole?
systole would be extremely high, diastole would be extremely low. Walls do not move, it is completely dependent upon the blood flow.
Are the veins stretchy or stiff?
Very stretchy, thats why pressure doesnt really change in the veins.
What are two things that can increase pulse pressure?
Higher stroke volume, and higher wall resistance.