Exam 1 Lec1-6 Flashcards

1
Q

Who are the historic figures in the evolution of surgery?

A
  • Aristotle
  • Grandfather of Comparative anatomy
  • First to describe the absence of gallbladder in horses
  • Andreas Vesalius (1500s)
  • Father of modern human anatomy
  • Ambroise Pare (1500s)
  • Innovative wound treatments
  • Turpentine ointment more effective than boiling oil
  • Controlling hemorrhage by ligation
  • Gunshot and shrapnel (small pieces of metal in wound) wounds in horses
  • John Lister (1800s)
  • Pioneer of antiseptic surgery by Louis Pasteur concepts
  • William T.G. Morton (1800s)
  • Dentist
  • First use of ether
  • William Roentgen
  • Discovered X-rays 1895
  • 1896 first medical use of X-rays. Thomas Edison discovered the fluoroscope in 1896
  • John Hunter (1700s)
  • Anatomist and surgeon
  • Began using the scientific approach to medicine and surgery
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2
Q

Give examples of major developments in surgery and the impact/outcomes for patients?

A
  • Caesarian Section
  • 272 BC first time performed
  • Mother died of poisoning, but baby saved
  • High mortality in live mothers
  • Uterus closing improved survival
  • Routine in VetMed, low mortality
  • Surgical technique William Halsted
  • Early 1900s
  • Meticulous
  • Hemostasis
  • Local anesthetics
  • Patient care
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3
Q

What are some recent advances and how do they impact modern surgical techniques?

A
  • Research in shock, trauma, wound healing
  • Perioperative care
  • Structured residencies programs ACVS 1967
  • Minimal invasive surgery
  • Laparoscopically assisted gastropexy
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4
Q

What are the Instrument Categories?

A
  • Scalpels
  • Scissors
  • Needle holders/Needle drivers
  • Tissue forceps
  • Hemostatic forceps
  • Retractors
  • Miscellaneous instruments
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5
Q

Scalpels

  • *Slide cutting**
  • *Blade should be perpendicular to the skin surface**
A
  • Used to incise tissue
  • Reusable No. 3 and 4 with detachable blades
  • Available disposable blades/handles
  • Some with Retractable blade shield

Blades
No. 10: small animal surgery common
No. 15: smaller version of 10, precise incisions in smaller tissue
No. 11: Stab incisions into fluid-filled spaces/organs
No. 12: Curved angle, limited applicability, cats elective dissection onychectomy (declawing)

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6
Q

Types of scalpel grips and uses

A
  • Pencil grip: 30-40 degrees. Shorter, finer, more precise incision. Angle reduces cutting edge contact, best for long incisions.
  • Fingertip grip: Best accuracy and stability for long incisions
  • Palmed grip: Strongest hold, allows exertion of great pressure on the tissue, often unnecessary
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7
Q

Scissors

  • Type of point
  • Blade shape
  • Cutting edge

Held with the tips of the thumb and ring finger. Index finger resting on the shanks near the fulcrum. Rings should be kept near the distal finger joint

A
  • Curved: greater maneuverability and visibility
  • Straight scissors: greatest mechanical advantage when cutting tough or thick tissue
  • Metzenbaum (Metz, Nelson, delicate, or tissue scissors): more delicate than Mayo scissors. Sharp and blunt dissection or incision of finer tissues
  • Mayo scissors: used for cutting dense, heavy tissue, such as fascia.
  • Iris Scissors (curved or straight): delicate, ophthalmic procedures and other meticulous surgeries, fine cuts
  • Bandage scissors: blunt tip to reduce risk of cutting skin.
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8
Q

Scissors Grips

The larger the angle between the blades when cutting, the less the scissors stabilize the tissue and the less accurate the cut is

Using the end of the blade stabilizes tissue more securely, and allows a more precise cut

A
  • Wide-based Tripod Grip
  • Most efficient hold
  • Thumb and ring finger through the rings.
  • Middle finger on top of ring finger
  • Index finger along handles towards fulcrum.
  • Backhand Grip
  • Typically for cutting from left to right (less awkward)
  • Thumb and middle finger through the rings
  • Handle resting on 3rd and 4th fingers
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9
Q

Should the scissors be completely closed while making incision? Why?

How are scissors used during blunt dissection? What typed of tissue is to be avoided?

A

They should not be completely closed is the cut is to be continued because it causes a ragged incision.

They should be nearly closed, advanced, and nearly closed again.

-Blunt dissection: (e.g., separation of tissue by inserting the points and opening the handle) may be used to separate loosely bound tissues, such as muscle or fat, or to undermine skin edges
avoid tougher tissue or where precise cuts are possible.

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10
Q

Needle Holders

A
  • Grasp and manipulate curved needles
  • Long needle holders facilitate working in deep wounds
  • *Grasp suture only at the suture’s end, where it will not be in a surgical knot!**
  • Needle holder finely serrated or smooth jaws: for holding suture, prevent fraying or cutting suture.
  • High-quality: noncorrosive, high-strength alloy, glare-free finish. Diamond surface tips or tungsten carbide (replaceable inserts)
  • *Mayo-Hegar & Olsen-Hegar: ratchet lock just distal to the thumb. MEDIUM to COARSE needles
  • *Castroviejo: spring and latch mechanism for locking
  • *Mathieu: ratchet lock at the proximal end of the handles, which permits locking and unlocking simply by progressively squeezing the handles together.
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11
Q

Needles

A
  • *Needles should be placed perpendicular to the needle holder. **
  • Parts of needle: point, body/shaft, Swaged (eye) end.

Needle generally grasped near its center: advances through tissue with greatest force and less risk of breakage

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12
Q

Needle holders Grips

A
  • Palmed grip: no fingers are placed in the rings, upper ring rests against the ball of the thumb. Strong driving force but less precision
  • Thenar grip: the upper ring rests on the ball of the thumb and the ring finger is inserted through the lower ring. Good mobility, but handles pop apart when releasing, tissue movement.
  • Thumb-ring finger grip: thumb is placed through the upper ring and the ring finger through the lower ring. Best precision and preferable for delicate tissue.
  • Pencil grip: Used with Castroviejo needle holders.
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13
Q

Tissue Forceps

A
  • Tweezer-like, non-locking instruments used to grasp tissue.
  • Tissue forceps with large teeth should not be used to handle tissue that can be easily traumatized
  • DeBakey forceps: smooth tips, for delicate tissue, such as viscera or blood vessels
  • Brown-Adson forceps: have small serrations on the tips that minimize trauma but facilitate holding tissue securely.
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14
Q

Tissue Forceps

A
  • Tweezer-like, non-locking instruments used to grasp, stabilize, expose tissue layers during suturing, etc.
  • Tissue forceps with large teeth should not be used to handle tissue that can be easily traumatized
  • DeBakey forceps: smooth tips, for delicate tissue, such as viscera or blood vessels
  • Brown-Adson forceps: have small serrations on the tips that minimize trauma but facilitate holding tissue securely.
  • Generally used in the non-dominant hand
  • Should be held in the pencil position
  • Holding the shanks in the palm greatly limits maneuverability.
  • When not in use they can be palmed
  • When needles are grasped with forceps during suturing, they should be grasp perpendicular to the shaft.
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15
Q

Hemostatic Forceps

A
  • They are crushing instruments used to clamp blood vessels
  • Straight or curved tips vary in size from 3 inches (Mosquito hemostats) to 9 inches (Angiotribes)
  • Serration on the jaws of larger hemostat forceps may be transverse, longitudinal, diagonal, or a combination.
  • Longitudinal serrations: gentler to tissue than cross-serrations.
  • Serration extend from the tips of the jaws to the boxlocks
  • Kelly forceps: transverse serrations extend only over the distal portion of the jaws. Used on larger vessels.
  • Crile forceps: have transverse serrations that extend over the entire length of the jaw. Used on larger vessels.
  • Rochester-Carmalt forceps: are larger crushing forceps often used to control large tissue bundles, such as during an ovariohysterectomy. They have horizontal grooves with cross-grooves at the tip ends to prevent tissue slippage.
  • Satinsky forceps: Specialized cardiovascular forceps (e.g., Satinsky forceps) allow occlusion of only a portion of the vessel.
  • Ochsner forceps: have large teeth at the tip, which help prevent tissue slippage within forceps.
  • Allis Tissue Forceps: have interlocking sharp teeth; firmly grasps tissue that is going to be removed from the body.
  • Babcock tissue forceps: have broad, flared, and blunt grasping tips that are more delicate and can be used carefully on tissue remaining in the body (stomach).
  • Doyen intestinal forceps: non-crushing, occluding forceps with shallow longitudinal striations that are used to temporarily occlude the lumen of the bowel.
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16
Q

Retractors

A
  • Hand-held retractors and self-retaining retractors are used to retract tissue and improve visualization.
  • Ends maybe hooked, curved, spatula-shaped, or tooth.
  • Some maybe bent by the surgeon to conform to the structure or area of the body being retracted.
  • Hohmann: spatula-shaped
  • Malleable or ribbon: maybe bent
  • Senn (rake) retractors: small, double-ended retractors with three small, finger-like projections on the end and a flat, curved blade on the other
  • Army-Navy: larger, blunt broad blades on each end for retraction of large amounts of tissue.
  • Self-retaining retractors (e.g., Gelpi, Weitlaner) maintain tension on tissue and are held open with a boxlock or another device (e.g., a set-screw, such as in Balfour and Finochietto retractors).
  • Balfour retractors: retract abdominal wall
  • Finochietto: during thoracotomies.
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17
Q

Retractors

A
  • Gelpi: self-retaining, maintains tension on tissue, held open by boxlock or another device.
  • Weitlaner: similar to Gelpi, but with three theeth.
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18
Q

Miscellaneous Instruments

A
  • Magnifying loupes: helpful in improving visibility of small tissues, etc.
  • Specialized example: Arthrex Meniscal Knives
  • Suction tips:
  • Poole: not precise, sucking the pool
  • Yankauer
  • Frazier: very precise
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19
Q

Miscellaneous clamps and forceps

A
  • Backhaus towel clamp:
  • Allis tissue forceps:
  • Babcock

Orthopedics

  • Lempert, Ruskin, Kerrison
  • Duck-bill double action rongeurs
  • Bone holding forceps

Periosteal elevators

  • AO-round edge
  • AO-curved blade and straight edge
  • Freer

Orthopedics

  • Chisel
  • Mallet
  • Orthopedic wire
  • Wire twisters
  • *Jacobs chuck and key**

Neurosurgery

  • Lens loop
  • Small nerve root retractor
  • Tartar scraper
  • Freer dissector
  • Large right angle nerve root retractor.
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20
Q

Suture Materials and Patterns

A
Suture function
Size
Characteristics 
Suture materials
Suture selection: wound repair, hemostasis,  healing supporting tissue layers. Depending on type of tissue and anticipated duration of healing.  
Needles 
Suture Patterns
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21
Q

How long does suture need to function according to the type of tissue?

A
  • Muscles, subcutaneous tissue, skin: a few days of support needed
  • Vessels: hours of ligature support until clot forms
  • Fascia: weeks
  • Tendons: months

Individual patient variation further affects suture choice

  • Infection
  • Obesity
  • Malnutrition
  • Neoplasia
  • Drugs (e.g., steroids)
  • Collagen disorders
  • Hypoproteinemia
  • Radiation therapy
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22
Q

What is the primary function of suture?

What are some ideal characteristics of suture?

A

Maintain apposition of tissue until wound’s tissue strength returns

  • Easy to handle
  • Reacts minimally in tissue
  • Noncapillary
  • Nonallergenic
  • Noncarcinogenic
  • Nonferromagnetic
  • Absorbs with minimal reaction after the tissue has healed
  • Holds securely when knotted
  • Inhibits bacterial growth
  • Resists shrinking in tissue
  • *The ideal suture material does not exist**
  • *surgeons must choose a suture that most closely approximates the ideal for a given procedure and tissue**
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23
Q

Suture Size, Flexibility.

A

USP: United States Pharmacopeia

  • 12-0 being the smallest
  • 7 being the largest
  • Dimensions from fine to coarse
  • Smallest diameter suture that will adequately secure wounded tissue should be selected: minimize trauma as it passes through tissue, reduce the amount of foreign material left in the wound.
  • *There is no advantage in using suture that is stronger than the tissue**

Flexibility

  • Torsional stiffness and diameter determines it
  • Ligating vessels or performing continuous suture patterns
  • Less flexible can not be used on small vessels
  • Nylon and surgical gut are relatively stiff compared to silk suture.
  • Braided polyester sutures have intermediate stiffness
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24
Q

Suture surface characteristics and coating

Which sutures have Capillarity and which don’t?

A
  • It influences the ease with which it is pulled through tissue (amount of friction or “drag”) and the amount of trauma caused.
  • Smooth surfaces suture: for delicate tissue, require greater tension to ensure good apposition of tissues. Have less knot security.
  • Braided sutures: have more drag than monofilament sutures. They are often coated to reduce capillarity (Capillarity is the process by which fluid and bacteria are carried into the interstices of multifilament fibers).
  • Polyglycolic acid, silk have degrees of capillarity (macrophages are too big to enter interstices = very small space)
  • Monofilament are considered noncapillary: coating reduces capillarity.
  • *Capillary sutures should not be used in contaminated or infected sites**
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25
Q

How is Knot tensile strength measured?

What is knot security, holding capacity?

A
  • It is measured by the force in pounds that the suture strand can withstand before it breaks
  • Sutures should be as strong as the normal tissue
  • *Tensile strength of the suture should not greatly exceed the tensile strength of the tissue**

Relative knot security: is the holding capacity of a suture expressed as percentage of its tensile strength

Knot holding capacity of a suture: is the strength required to untie or break a defined knot by loading the part of the suture that forms the loop.

Tensile strength is the strength required to break an untied fiber with a force applied in the direction of its length.

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26
Q

How are Suture Materials Classified?

A

Structure

  1. Monofilament: less tissue drag, no interstices, break easily by needle drivers. Nonwicking, more memory, does not handle well.
  2. Multifilament: generally more pliable (ease of handling, adjust knot tension and secure knots) and flexible, may be coated. Wicking, less memory, good handling.

Behavior in Tissue

  1. Absorbable: degraded. Ex: Surgical gut, Chromic Gut. Lose tensile strength 60 days.
  2. Nonabsorbable: encapsulated or walled off by fibrous tissue.

Origen

  1. Synthetic: synthetic polymers broken down by hydrolysis
  2. Organic: Organic Absorbable CAT GUT = gradually digested by tissue enzymes and phagocytized.
  3. Metallic
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27
Q

Absorbable Organic Cat Gut Suture
What is is made of?
Does it elicit inflammation?
What is tanning?

A

Most common made from submucosa of sheep intestine or the serosa of bovine intestine. 90% collagen, broken down by phagocytosis. *Elicits a notable inflammatory reaction.

  • Tanning (cross-linking of collagen fibers) slows absorption
  • Increased tanning implies prolonged strength and reduced tissue reaction
  • Available in plain, medium chromic, or chromic.
  • Knots may loosen when wet
  • Rapidly removed from infected sites, quickly degraded in catabolic patients
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28
Q

Synthetic Absorbable
What process brakes it down?
How does Alkaline environments influence it?
Which one is stable in infected wounds?
Which one is acceptable to use in E. coli contaminated area/urine?
-Polyglactin 910, Polyglycolic acid, Polydioxanone, Polyglyconate, Glycomer 631.

A
  • Broken down by hydrolysis
  • Minimal tissue reaction
  • Not influence by digestive enzymes
  • *Polyglactin 910 and Polyglycolic acid degraded rapidly in Alkaline environments but stable in contaminated wounds. Rapidly degraded in infected urine**
  • *E. coli acceptable: Polydioxanone, Polyglyconate, Glycomer 631. **
  • *Proteus spp. and P. mirabilis: accelerate degradation (7days).
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29
Q

Nonabsorbable Suture

  • Organic
  • Synthetic
  • Metallic
A
  • Silk: most common organic nonabsorbable. *Braided multifilament made by a special silkworm.
  • Excellent handling, used in cardiovascular procedures.
  • Coated or uncoated
  • Does not maintain sufficient tensile strength after 6 months = not used in vascular grafts
  • Avoided in contaminated sites

Synthetic nonabsorbable

  • Braided multifilament: polyester or coated caprolactam
  • Monofilament threads: polypropylene, polyamide, orpolybustester
  • Typically strong and induce minimal tissue reaction
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30
Q

Cable ties

A

Should never be implanted in the body. Toxic substances released during degradation = abscess or tumor formation.

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31
Q

Metallic sutures

  • Standard for judging knot security*
  • Standard for judging tissue reaction
A
  • Stainless steel most common, and stable in contaminated sites.
  • Surgical steel is strong and inert with minimal tissue reaction
  • Knot ends evoke inflammatory response
  • Tendency to cut tissue
  • May fragment and migrate
32
Q

Considerations in Suture Selection
Suture selection for Skin
Subcutaneous Sutures

A
  • Length of time required to help wound or tissue
  • Risk of infection
  • Effect on wound healing
  • Dimension and strength

Skin Sutures

  • Monofilament should be used
  • Synthetic monofilament nonabsorbable have good knot security and relatively non-capillary
  • Absorbable can be used but still need to be removed bc body fluids is what allows absorption

Subcutaneous Sutures

  • Are used to obliterate dead space and reduce tension on skin edges
  • Multi or monofilament absorbable material preferred
33
Q

Suture selection for Abdominal Closure

A
  • Rectus fascia may be closed with interrupted or continuous suture pattern
  • Most common pattern is simple continuous, which a strong nonabsorbable or standard absorbable monifilament suture with good knot security should be used (e.g., polypropylene, polybustester, polydioxanone, polyglyconate).
  • One size larger than normal
  • Knots are to be tied carefully. Three or four square knots (six or 8 throws)
  • Standard absorbable suture preferred
34
Q

Suture selection for Muscle, Tendon, Parenchymal Organs (liver, Spleen, Kidney), Hollow Viscus Organs (trachea, GI, Bladder).

A
  • Muscle has poor holding power and it is difficult to suture
  • Absorbable or nonabsorbable ok
  • Sutures need to NOT be parallel to the muscle fiber bc they are likely to pull out.

Tendon

  • Should be strong, nonabsorbable, and minimally reactive.
  • Taper or taper-cut needle is less traumatic
  • Largest suture that will pass without trauma

Parenchymal organs
-Absorbable monofilament

Hollow Viscus Organs

  • Absorbable monofilament recommended
  • Nonabsorbable may be in urinary bladder or gallbladder. May be extruded into lumen when implanted in intestine
  • **Polyglycolic acid (Dexon brand) suture rapidly dissolves when in sterile urine (6days) or infected urine (3 days).
35
Q

Suture Selection for Contaminated Wounds

Which material is to be avoided and which is preferred?

A
  • Sutures should be avoided in highly contaminated or infected areas
  • Avoid multifilament nonabsorbable
  • Absorbable material preferred
  • Surgical gut should be avoided
  • Synthetic monofilament nylon and polypropylene may elicit less infection
36
Q

Sutures for vessels and vascular Anastomoses

A
  • Absorbable suture to be used

- Monofilament nonabsorbable for Anastomoses, such as polypropylene

37
Q

What does the selection of Surgical Needles depend on?
What are surgical needles made from?
What is surgical Yield, ductility, sharpness?
What are the basic components, types, and sizes of needles?

A
  1. the type of tissue to be sutured
  2. Topography of the wound
  3. Characteristics of the needle
    * Stainless steel: strong, corrosion free, does not harbor bacteria.*

Surgical Yield: the amount of angular deformation a needle can withstand before becoming permanently deformed.

Ductility: the needle’s resistance to breaking during bending pressure

Sharpness: angle of the point and the taper ratio of the needle. The sharpest needles have a long, thin, tapered point with smooth cutting edges.

-Components: 1. Needle point 2. Needle body/shaft 3. Swaged end
-Types: holes 1. Closed 2. French
-Shapes/sizes:
A. Straight
B. 1/4 opthalmic procedures
C. 5/8 require more pronation and supination of the wrist, but easier to use in confined locations than 3/8 needle
D. 1/2 most common
E. 3/8 most common

38
Q

What are the different point types in needles?

A
  1. Taperpoint
  2. Tapercut
  3. Regular cutting
  4. Reverse cutting
  5. Spatula point
  6. Blunt point
39
Q

How are suture patterns classified?

What is appositional? Inverting? Everting?

A

A. Interrupted
B. continuous

  1. By the way the oppose tissue
    - appositional: one tissue edge apposed to another
    - Everting: turn the tissue edges outward, away from the patient and toward the surgeon
    - Inverting: turn tissue away from the surgeon, or toward the lumen of a hollow viscus organ
  2. By which tissues they primarily appose
    - Subcutaneous: eliminate dead space. Some apposition of skin so that less tension is placed on skin sutures. Generally simple continuous pattern. Simple interrupted for drainage
    - Subcuticular/Intradermal: May be used in place of skin sutures. They reduce scarring, eliminate need for suture removal. Suture line begins by burying the knot in the dermis, then advanced in the dermal tissue. Bites are parallel to the long axis of the incision. No visible sutures externally. Absorbable material with a cutting needle preferred.
40
Q

Name and describe 6 Interrupted Suture Patterns

A
  1. Simple interrupted: Know is offset to that it does not rest on top of the incision. One side to the opposite side and tying. Ends of sutures are cut long enough to allow removal. 2-3 mm away from the skin edge Place sutures from right to left in horizontal fashion.
    - disruption of a single suture does not cause the entire line to fail. It takes more time than continuous patterns. More foreign material, more knots in the wound.
  2. Horizontal mattress: used primarily in areas of tension. Can be placed rapidly. Often cause tissue aversion (care to be exercised to appose, rather than evert, tissue margins). Suture should be angled through tissue to pass just below the dermis. 4-5 mm separation Can be bolstered using rubber stents and buttons.
  3. Cruciate: Create an “X” two simple interrupted sutures placed parallel to each other and tied across. Low to moderate tension. Less material than with single interrupted. Affords security of an interrupted pattern.
  4. Vertical mattress: Stronger than horizontal mattress. Preferred when addressing tension in skin closure. Less disruption of blood supply. 4 mm from skin edge. Time consuming. Eversion of skin margins is less of a problem than with horizontal mattress. Can be bolstered using rubber stents and buttons.
    * *Stents: placing padding material beneath the sutures loop is stenting**
  5. Halstead: An interrupted pattern that is a modification of a continuous Lembert pattern. Provides exact skin approximation
  6. Gambee: interrupted pattern used in intestinal surgery to reduce mucosal eversion, also reduces mucosal inversion and may reduce wicking of material from lumen to exterior.
41
Q

Name and describe Continuous Suture Patterns
Which suture pattern is used to close the linea Alba and subcutaneous tissue? Which one is perpendicular to the incision? Which one is advanced above and below the incision line?
Which pattern is a variation of the vertical mattress and used often to close hollow viscera? Which patterns are used for suturing hollow organs?

Old Suture Pattern: Parker-Kerr Oversew

A
  1. Simple continuous: series of simple interrupted sutures with a knot on either end. Maximum tissue apposition. Air and fluid tight. Used to close the linea alba. Care with intestinal anastomosis. Needle passes Perpendicular to the incision and suture is advanced above the incision line at a diagonal.
  2. Running: Suture is advanced above and below the incision line and it is not as secured as less tissue is purchased.
  3. Ford Interlocking: Modification of a simple continuous pattern. Each passage through tissue is partly locked. Each pass is linked to the previous passage as suture exits the tissue through a created loop of material. May be placed quickly. May appose tissue better than simple interrupted pattern Provides greater stability than simple continuous in the event of partial break along the line. Larger amount of material needed and more difficult to remove.
  4. Lembert: A variation of the vertical mattress applied in a continuous fashion. It is inverting pattern that often is used to close hollow viscera.
  5. Connel: Inverting patterns used to close hollow organs. Watertight seal is created by the inversion. Connell enters the lumen.
  6. Cushing: Inverting patterns used to close hollow organs. Watertight seal is created by the inversion. Cushing enters the submucosa only.
    * *Calculogenic closures but monofilament suture that is rapidly absorbed negates this concern.
42
Q

Tendon Sutures

A

Used to approximate severed ends of a tendon or to secure one end of a tendon to bone or muscle.

  • Kessler locking-loop
  • Bunnel-Mayer
  • Krackow
  • Three-loop pulley
  • Locking loop
43
Q

Suture Materials and Patterns Large animal
What factors do you consider when selecting suture material for a procedure?

What is the typically size use for large animal sutures?

A
  1. Size and chemical make-up: Natural vs. synthetic. Strength of closure, how long does it need to last?
  2. Absorbable vs. nonabsorbable: is the ligature inside or outside the body? What about inflammatory response?
  3. Monofilament vs. braided (multifilament): Concerns with wound contamination.

Large animals
Typically use 2-0 for SQ
2 or 3 for linea alba

44
Q

What are the Suture selection principles?

A
  1. Suture strength = to normal tissue where it is placed
  2. Tensile strength reduction over time should correspond to healing of the affected tissue
  3. Suture is not needed after the wound is healed
  4. The strength of wound is more dependent on the tissue’s ability to hold the suture than the suture material itself.
  5. Elastic suture for skin closures (edema considerations)
  6. High stiffness Suture for abdominal closure, herniorraphy, prosthesis, etc.
  7. Oversized suture will WEAKEN your closure due to tissue reaction, bigger not always better.
  8. Wounds under tension: increasing the number of sutures or tension relieving pattern better than increasing suture size.
45
Q

How long do internal organs and SQ tissue usually take to heal?

Fascia?
Skin?

A
  • Internal organs, SQ = few days, full strength in a couple of weeks
  • Fascia: slowly 14 days, full strength in a couple of months. Linea alba = 8 weeks
  • Skin heals based on the quality of apposition: 1 day, primary incision 10-14 days, full strength <30 days.
46
Q

What are some commonly used sutures in Large Animal procedures?

A
  • Vicryl: braided, medium term, absorbable
  • Monocryl: monofilament, medium term, absorbable.
  • PDS II: Long term, absorbable, monofilament.
  • Nonabsorbable synthetic braided: Ethibond, Supramid, Braunamid
  • Nonabsorbable synthetic monofilament: Ethilon, Prolene, Fluorofil.
47
Q

What does the body uses to degrade absorbable suture?

A
  • Inflammatory response, which increases by suture size increase, volume of knot. Number of throws on knot not as important.
  • *Use the smallest suture possible**
48
Q

Needle selection
What are the most common sizes and shapes of needles?
How does the needle point shape affect its use?

A
  • 3/8 circle
  • 1/2 circle
  • 1/4 used opthalmologic surgery
  • 5/8 used in confined or deep locations
  • Goal is to reach across both sides of the wound with the needle

Shape of point

  • Taper point: round needle body, does not enlarge hole as it passes. Best for delicate tissue
  • Reverse cutting: has cutting edge on the outer (convex) side. Stronger needle, less risk of tissue cut out, best for skin and fibrous tissue.
  • Conventional cutting: uncommon
49
Q

What is the Buhner needle and S needle used for?

A
  • Buhner needle: used to purse string prolapses
  • S needle: used to close a cow skin, negates the need for needle drivers, easier to punch through thick skin, suture on reel.
50
Q

What is dehinscence of incision? How to prevent it?

What factors contribute to making a secure knot?

A

opening of an incision due to weakened ligature or bad knot bc it is the weakest point in the suture.

  1. Suture type: memory and coefficient of friction. Body fluids can change frictional behavior of suture
  2. Number of throws: 2-0 PDS (polydiaxonone) or Nylon: 4 throws are needed for a secure ligature. Larger suture need 5 throws = #2 or #3 Vicryl (polyglactin 910) or #2 PDS (polydioxanone). Need additional throws if tying to a loop.
  3. Suture tag length: at least 3mm
  4. Knot security decreases as suture size increases
51
Q

What suture would you select for the skin? Linea alba? Delicate tissue?

A

Skin

  • Monofilament: less bacterial transport into tissues
  • Nonabsorbable: Polypropylene (Prolene) or Nylon
  • Simple interrupted with no tension (USP 2-0). +/- tension relieving patterns (larger suture 0, 1, 2).
  • Bites should be 5mm from skin edge: collagenase activity sutures may pull through

Linea alba

  • Polyglactin 910 (Vicryl) or Polydiaxonone (PDS)
  • Size #2-7 (2 or 3 most common)
  • Cattle: Cat gut bc is cheap, but too much inflammation in horses.

Delicate tissue

  • Subcutatneous , GI organs
  • PDS, Vicryl (polyglactin 910) Monocryl (poliglecaprone)
  • USP 2-0
  • GI tract: Lembert, simple continuous with Cushings.
52
Q

What type of suture do you use for contaminated wounds?
What suture is commonly used on farm animals?

For suture removal, how to go about it?

A

-Monofilament, inert-nonabsorbable, elastic allows for swelling

Farm animals: chromic gut, suture on a reel

  • Supramaid
  • Braunamid

Removal
-take out every other suture every 1/3 initially for wounds under tension

53
Q

Skin Staples

A
  • Inert
  • Fast to put in
  • Only wounds with no tension
  • Removal can be tough
  • NOT for foals or mini colics!
54
Q

What are some inverting suture patterns common in LA?

How are wounds under tension sutured?

A

Inverting the tissue edges to help make a seal
Uses in: GI tract, urinary bladder, uterus
-Utrecht: used in uterus 45 degree angle
-Cushing: GI, urinary bladder. Often combined with continuous first.
-Lembert: GI, urinary bladder. Interrupted or continuous. Avoid making a cuff of tissue deep to your suture line

Wounds under tension

  • Tension impedes healing, impairs blood supply, prevents perfect apposition, shears stress on wound.
  • preferably use limb immobilization
  • add more sutures
  • use tension-relieving techniques
  • *Not use bigger suture**
  • Use of stents: prevent pull-through. Staged removal if needed. always combined with suture patterns
  • Combination suture patterns
  • Keep skin tension lines in mind
  • Use relief incisions: next to primary wound and left to heal by second intention
  • Walking sutures: using your suture to ‘pull’ the skin over the top of the defect. Even out tension, Obliterate dead space, No closer than 2-3cm apart. Can increase inflammatory response with the extra suture
  • Vertical mattress: Less impingement of blood supply compared to horizontal mattress. Interrupted only. Bites are perpendicular to the edge
  • Horizontal mattress: Strong tension relieving, will not tear through tissue, but tends to impede blood supply. Rarely used without stents. Can apply in continuous pattern. Visible bites are parallel to edge.
  • Near-far-far-near: Interrupted only. Excellent apposition and tension relief. Most secure in wound
  • Ford interlocking: Mild tension relieving continuous pattern. Reduces suture disruption if one part breaks, good apposition, commonly used to close the skin on cow flank. C-section, need a few simple sutures at the bottom for potential drainage sites.

Langer’s line: relaxed skin tension lines
-Incision parallel = least tension

55
Q

What is the material in Meshes for Large Defects?

A
  • Polyglactin 910 (Vicryl)

- Polypryopylene (Prolene)

56
Q

What are some of the differences between LA and SA Sutures, etc.?

A
  • LA need punching through the skin, thick!
  • Tightness on skin sutures: snug vs. lose on SA
  • More frequently use surgeon’s throw
  • PDS II NOT preferred for closing linea alba.
  • Rarely use intradermal patterns
  • LA bigger incisions = longer suture!
  • Sometimes you stand on your head Lol.
57
Q

Special Surgical Instruments and Equipment LA

What is included in a LA General Surgery Pack?

A

a. Needle drivers
- Mayo-Hegar
- Olsen-Hegar
b. Scalpel handles
- #3 blades: 10, 11, 15
- #4 blades: 20, 22
c. Scissors
- Mayo
- Metzenbam
- Lister Bandage scissors
d. Towel clamps
- Backhaus Towel Clamp: penetrating
- Lorna Edna Towel Clamp: non-penetrating
e. Hemostats
- Mosquito forceps
- Kelly forceps
- Rochester Oschner: only on tissue to be temoved. Wicked teeth on the tip.
- Rochester Carmalt forceps
f. Thumb forceps
- Brown-Adson forceps: delicate tissue
- Adson tissue forceps: Rat tooth = traumatic
- Russian forceps
g. Tissue forceps
- Allis tissue forceps: traumatic
- Babcock tissue forceps: for delicate tissue, uterus, intestine.
- Foerster Sponge forceps: to handle sterile dressing or reach far into body cavity
h. Hand-held retractors
- Senn retractor: small, finger retractor
- Army-Navy retractor
- Malleable retractor
- Hohmann retractor
- Gelpi: self retaining retractor
- Weitlaner: muscle retraction during orthopedic surgery
- Balfour retractor: abdominal retractor in small animal = anal fissure retractor in LA
i. Suction tips
- Poole Suction tip
- Yankauer Suction tip: gets plug easily

58
Q

What are some special LA GI instruments?

A

Doyen Intestinal forceps: occlude the lumen with minimal trauma

Gastrointestinal Staples
-Faster than sutures, inert, reduce contamination, preserve blood supply, use in areas of limited accessibility. Costly, leakage is possible, may be limited in tissue thickened (edema), trained personnel.

TA-90 (Thoracoabdominal Stapler)
-does not cut, only double row of staples

ILA (Intestinal Linear Stapler)

  • Gastrointestinal Anastomosis
  • Linear stapler
  • Cuts and divides at the same time

LDS (Ligating dividing stapler)
-Ligating and useful on mesenteric vessels

Other Staples

Quick ligation of vessels
-Can slip off easily! be careful!

Skin staples

  • Rapid closure of surgical incisions
  • Have been associated with surgical site infections
  • Appose or evert, NEVER INVERSION
59
Q

Special Urogenital Instruments Equine
Which equine emasculator attaches to a drill?
Which ones simultaneously crush and cut?
Which one cuts and separate handle is 3rd handle?
Which one crushes only?

A
  • Henderson: twists the cord, attached to a drill
  • Serra and Modified White
  • Reimer: crush and separate cutting handle
  • Sands: crushes only
60
Q

Castration in Ruminants
What instrument is to be used on young animals only and why?
Which instrument cuts the scrotum?
What instrument is mostly used by the producer?
Which castration instruments are used in more mature animals?

A
  • Burdizzo crushes only and it is to be used in young animals because older thinker tissue may not get a complete crush
  • Newberry Knife: cuts the scrotum and prevents accidental cutting of other structures. Perpendicular cuts do not allow for ventral drainage.
  • Elastrator bands: used by producer, young animals only, difficult to provide analgesia for several weeks
  • Emasculators & Henderson are used in mature animals.
61
Q

What surgical instrument is used for ovariectomy through colpotomy in mares?

A

-Chain Ecraseur: removal of other masses with blood supply

62
Q

Arthroscopy Equipment

A
  • Tower
  • Arthroscope
  • Light cable and Fluid line
  • Instrumentation: Cannula & Obturator, Ferris Smith Rongeurs (alligator like hemostats), Currettes (tiny spoon to clear tissue), Probe 30 or 70 degrees angle.

Bone Plates and Screws

  • DCP: Dynamic Compression Plates: limited contact CP = -LC-DCP.
  • Locking Compression Plate
  • Orthopedic screws
  • Locking Cortical Screw
63
Q

Special Respiratory Equipment

A
  • Guarded Epiglottic Hook Knife
  • Lasers: Light Amplification by Stimulated Emission of Radiation. Commonly used in Equine URT surgery. Scar tissue is less flexible, can get into tight space of larynx/pharynx
  • Can perform standing through an endoscope. Laser passes through instrument channel
  • Lasers generate intense beam, energized molecules emit certain wavelength of light that can cut, seal or vaporize tissue.
  • *Negative effect of lasers on wound healing of primary closed incision = Area of thermal necrosis**
  • Requires specialized training, equipment is expensive, can result in excessive thermal damage.
  • Decreases bleeding, swelling, pain, kills bacteria as it cuts, precise cutting, can go through the endoscope.
  • Uses of laser: Uterine cysts, skin tumors, neurectomy, fusing hock joints, hemostasis during laparoscopic surgery.
64
Q

What are the processes that occur during the phase of wound healing?

Which is NOT a cardinal sign of inflammation?

A
  1. Hemostatis
  2. Inflammation
  3. Proliferation
  4. Maturation
  • Neutrophilia is NOT a cardinal sign of inflammation
  • *Redness, Heat, Swelling/Edema, Pain, Loss of function**
65
Q

Which are the signs of normal Surgical Inflammation?

What are signs of abnormal surgical inflammation?

A
  • Acute inflammation
  • Mild or moderate: dependent on procedure and body system
  • Local and not systematic inflammation, which is abnormal
  • Short duration: goes away soon and is limited to primary wound closure

Abnormal inflammation

  • Prolonged
  • severe
  • Signs of infection
  • Systematic signs: underlying pathology
66
Q

What tare the phases of wound healing and how long are they?

What triggers/mediates vasodilation redness & heat?

A
  1. Hemostatis: within minutes to hours. The goal is to stop bleeding while still maintain perfusion. Balance between vasoconstriction and vasodilation.
    - Starts with Endothelial cell disruption
    - Immediate vasoconstriction
    - Exposure of vWF platelet activation and aggregarion
    - Coagulation cascade: Intrinsic and extrinsic pathway. Final common pathway: protrombin (II) -Thrombin (IIa) -Fibrinogen (II) - Fibrin (Ia) - XIIa = cross-linked fibrin clot (mesh)
  2. Inflammation: 4-6 days.
    -Endothelial cells release vasodilators (Histamine, Neutrophils, Lymphocytes, Phagocytes, complement), which increase blood flow.
    -Post-capillary venule leakiness: Protein leakage due to increased inflammatory cell and mediator infiltration. EDEMA: fluid in subcutaneous space.
    =Osmotic pressure decreased
    =Increased blood viscosity
    =Increased interstitial pressure
  3. Proliferation: 4-24 days
  4. Remodeling: 21 days to 2 years
67
Q

What does Edema facilitate? What are signs associated with edema?

How does vascular congestion occur?

A

Facilitates delivery of soluble factors and cells
-Pain and loss of function

Vascular congestion

  • Fluid loss to edema
  • Hemoconcentration
  • Reduced velocity of blood flow
68
Q
  1. Inflammation
    what is this phase also called?
    What are the stages? What cells participate in each stage?
    What is the function of this phase?
    When are Leukocytes recruited and by what?
    What is Neutrophil diapedesis?
    Which cells are the first line of defense?
    When does the early phase end?
A

-A.K.A “debridement phase”

Two stages

  1. Early: neutrophil recruitment
  2. Late: Monocyte transformation

Function

  • Prepares the body for the next phases of wound healing
  • Removes dead tissue and foreign material
  • The severity of the trauma affects the intensity of inflammation and the extend of scar tissue formed

Leukocytes

  • Recruited by chemoattractants (cytokines and chemokines from coagulation) from neutrophils
  • Initiate: rolling, activation, tight adhesion and transmigration of cells through microvascular endothelium.

Neutrophils

  • Diapedesis: the passage of blood cells through intact capillary walls. It is encouraged by increased capillary permeability
  • Occurs within minutes and peaks 1-2 days after injury
  • Neutrophils are the first line of defense against contaminated wounds.
  • Cleaning of wound: Destroy debri, phagocytose bacteria, Monocytes come over next
69
Q
  1. Late Stage

What is the role of Monocytes? where do they migrate from?

What happens if Inflammation does not resolve?
How is the inflammatory phase modulated by clinicians?

A

-Monocytes migrate from vasculature: Monocytes transformed into macrophages

Macrophages: proinflammatory functions.

  • Help orchestrate all phases of wound healing
  • Stimulate proliferation of dermal, endothelial and epithelial tissues.
  • Help with remodeling phase.

Resolution of Inflammation
-Each of the pathways need to be haltered or reversed.
-Apoptosis of cells
Not always work**
-Chronic, suppurative inflammation and non-healing wound
-Excessive granulation tissue (proud flesh in horses)

Inflammatory phase modulation

  1. Proper surgical debridement
  2. Good hemostasis
  3. Adequate drainage
  4. Medications
    - Steroids: inhibit phospholipases, before Arachinodic Acid
    - Cox-1 & Cox-2 inhibitors: NSAIDs Aspirin, indomethacin: Inhibit Cycloxygenase.
70
Q
  1. Proliferation
    When does granulation start?
    What are the three stages of proliferation?
A

DAY 5

  1. Fibroplasia: new granulation tissue formation by fibroblast made by three elements:
    a. Macrophages: debride, produce cytokines, growth factors, stimulate angiogenesis. Produce ECM, Type III collagen (immature), type I (mature) later.
    - Rapid gain day 7-14, when sutures are removed or may need to be left a little longer.
    b. Fibroblast: proliferate and make new extracellular matrix
    c. Blood vessels: carry O2, nutrients, metabolism, growth.
    - Necessary for other processes.
    - Very vascular
    - Protection from infection temporary
  2. Angiogenesis: new vessels formation.
    - New capillaries from pre-existing vessels
    - Regulated by macrophages and endothelium
    - VEGF
    - Increase tissue hypoxia = Increase vessel ingrowth
  3. Epithelialization
    - It covers the wound
    - Centripetal: around the wound skin
    - Grows flat, not mountains about 0.1-0.2 mm/day
71
Q
  1. Maturation
    What happens during this stage?
    How long can remodeling take?
A
  1. Continued epithelialization (thickening of epidermis)
  2. Wound contraction
    - Fibroblast differentiate into MYOFIBROBLAST under the influence of GF and cytokines.
    - They contain a alpha-smooth muscle actin.
    - Less distance for epithelial cells to migrate
  3. Remodeling
    - Conversion of granulation tissue into scar tissue
    - Involves Matrix Metalloproteinases MMPs “Demolition Team”:
    a. Collagenases
    b. Gelatinases
    c. Stromelysis
  • May take up tp 1-2 yrs, depending on the size of the wound.
  • Progresssive increase in tensile strength of wound
72
Q

When does healing stop? ideally and not ideally

What is healing by first intention vs. second intention?

A
  1. Wound edges meet: ideal
  2. Tension surrounding skin > force of myofibroblast: not ideal
  3. Reduced #s of myofibroblasts: not ideal
  4. Granulation tissue is proliferative (too much): epethilial cells can’t climb!

Primary intention healing

  • Means suturing within hours
  • Takes much less time than second intention

Second intention
-Takes weeks

73
Q

Dysfunction of the inflammatory response
What is shock?
What is SIRS?
What is the clinical definition of SIRS?
What molecules release (too much) leads to fever and can indicate abnormal fever?
What causes Hypothermia and shock?
What causes Tachycardia and Tachypnea?

A

Shock

  • Cascade of events that begins when cells/tissue are oxygen deprived from inadequate perfusion
  • Can lead to SIRS and MOD

SIRS

  • Systematic Inflammatory Response Syndrome
  • It can be sterile inflammatory diseases: nonseptic SIRS, burns, chemical aspiration, trauma.
  • It can be infectious Septic SIRS: Anaerobic bacteria, fungi, Viruses, etc.
  • Generally considered excessive response: “Cytokine storm”, Leukocyte dysfunction, delayed resolution of inflammation.

Clinical definition includes two underlying pathologic causes

a. Hyper or hypothermia
b. Tachycardia
c. Tachypnea
d. Laukocytosis or leukopenia: Neutrophils driven
e. Depression

Hyperthermia (fever)

  • IL-1, IL-6, TNF-alpha, PGE2.
  • They act on hypothalamus, increase the body’s temperature

Hypothermia

  • Hypoperfusion
  • Central blood sequestration

Tachycardia

a. Pain alone can do it
b. Dehydration leads to hypotension
c. Vasodilation: hypotension, decrease CO, Baroreceptor reflex = Increase HR

Tachypnea

a. Vasodilation Clotting dysfunction
b. Hypoperfusion
c. anaerobic cellular metabolism = lactic acidosis = metabolic acidosis. Not enough perfusion to tissues

74
Q

What is the primary cause of CBC Alterations 1st, 2nd, and 3rd. signs?

A
  • *Primarily from change in neutrophils**
    1. Leukopenia (<48 hrs): initial endothelial “stickiness.” Increased use
    2. Leukocytosis (>48 hrs). Release from sequestered areas. Bone marrow, spleen.
    3. Left shift (variable): immature neutrophils. supply < demand.
75
Q

Depression and Stress Response

A
  • Cytokines
  • Eicosanoids

Stress response

  • IL-1 & TNF-alpha = Increased Adrenocorticotropic hormone = Increased corticosteroids
  • Effects: Reduced Healing
  • Anti-inflammatory
  • Reduced activity/production of growth factors

Stress Leukogram

  • Variable by species
  • Due to endogenous (or exogenous) corticosteroids
  • Neutrophilia (usually mature, no bands): a higher neutrophil count in the blood than the normal reference range of absolute neutrophil count. (Neutropenia =occurs when you have too few neutrophils, a type of white blood cells.)
  • Lymphopenia
  • Monocytosis: more common in dogs. an abnormally high number of infection-fighting monocytes.
  • Eosinopenia