Exam 1 info Flashcards
Nausea- Retching- Vomiting-
Nausea- person’s subjective feeling of a need to vomit Retching- involuntary rhythmic diaphragmatic and abdominal contractions Vomiting- rapid, forceful expulsion of GI tract contents
Motion sickness
overstimulation of the labyrinth altering the chloringinic pathway. Generally caused by unusual motion, inaccurate interpretation of the visual stimuli. Example: flying, boat, driving, etc. (Women and children 2-15 age have reported increased frequency in motion sickness, children younger than 2 years rarely get motion sickness)
Pregnancy-
unclear neurotransmitter, multifactorial. Symptoms and NV generally occur between 6-12 week of prego- hyperemesis gravidarum- severe vomiting during prego.
Food poisoning/Viral Gastroenteritis
inflammation of the stomach and small intestines generally presents as acute vomiting and diarrhea, affects all age groups. Generally caused by rotavirus and norovirus.
Signs and symptoms of dehydration in children
-Dry mouth and tongue -Sunken and/or dry eyes -Sunken fontanelle -Decreased urine output (dry diapers for several hours) -Dark urine -Fast heart beat -Thirst (drink extremely eagerly) -Absence of tears when crying -Decreased skin turgor -Unusual Lethargy- sleepiness, decreased alertness, or irritability “Floppy” body -Lightheadedness- when sitting or standing -Difficulty waking up -Weight Loss -Noticeable decrease in abdominal size -Clothes or diapers fit loosely <3% body weight loss-minimal dehydration 3-9% weight loss-mild-moderate dehydration >9% weight loss-severe dehydration
Exclusion for Nausea and Vomiting
- Urine Ketone and BG with signs of dehydration in patients with diabetes (indicate (DKA or HHS) -Food poisoning that doesn’t clear up in 24 hrs -Severe abdominal pain that in middle or right lower quad -NV with fever and diarrhea may be infectious disease -Blood in vomit (ulcers, esophageal tears, or severe nose bleed) -Yellow skin or eye discoloration and dark urine (indicate hepatitis) -Stiff neck w/w-out sensitivity to brightness or normal light (indicate meningitis -Head injury w/ NV, blurry vision, or numbness -Person with glaucoma, BPH, chronic bronchitis, asthma -Pregnancy (severe symptoms) or breastfeeding -NV caused by cancer chemotherapy, radiation, metabolic disorders, CNS, GI, or endocrine -Drug-induced NV- adverse effect -Psychogenic-bulimia, anorexia -Chronic disease induced- gastroparesis w/ diabetes, GERD
Antacid and H2RA related to NV
Antacid- overindulgence in food or beverage or consumption of disagreeable food, relieve acid indigestion and sour stomach H2RA- overindulgence in food or beverage or consumption of disagreeable food, relieve acid indigestion and sour stomach
Bismuth Salicylate related to NV
ausea associated with consumption or nonulcer dyspepsia. Nausea, heartburn, and fullness
Phosphorated Carbohydrate Solution related to NV
nausea associated with food or beverage. Solution is a mixture of dextrose, levulose, and phosphoric acid. The hyperosmolar solution relieve NV by direct local action on the GI tract wall and decrease smooth muscle contraction
Antihistamine related to NV
generally safe and tolerated for nausea and vomiting related to motion sickness- These meds work due to the anticholinergic effects. Pregnant women should avoid
Meclizine
Meclizine is the only FDA approved non prescription. Meclizine is less sedating than DD. 25-50mg 1 hour before travel Onset- 60min duration= 24 hours
Doxylamine (sleepy)
In pregnancy, 10-12.5 mg w/or w/-out pyridoxine every 8 hr
Diphenhydramine (sleepy)
25-50mg every 6-8 hr children (6-12years) 12.5-25mg every 6-8 hr onset - 15-30 min and duration is 7-12 hours
Dimenhydrinate
50-100mg every 4-6 hr children(6-12years) 25-50mg every 6-8 hr children(2-6years) 12.5-25mg every 6-8 hr Onset- 15-20min and duration is 4-6 hours
doxylamine and diphenhydramine (DD) sideeffects
Both doxylamine and diphenhydramine (DD) have been used as off label treatments for nausea. Side effects- benign prostatic hypertrophy, dry mouth, confusion, dizziness, tremors, and constipation. Caution w/ opiates, psychmeds, beta blockers, and antiarrhythmic
Complementary therapy for NV
Ginger, Pyridoxine (Vitamine B6), Acupressure and Aromatherapy.
Ginger-
Ginger- use for nausea related to pregnancy, motion sickness and surgery, 250mg per day in 3-4 divided dosage. As effective as pyridoxine
Pyridoxine
Pyridoxine- water soluble B vitamin that is important in various metabolic functions, 1.3-2mg/day. NVP-10-25mg 3 times a day.
Acupressure
pressure on the wrist, pressure can be placed with two fingers or wrist band, vary from as need to 10min 3xday. Can throw off pace maker
Aromatherapy
peppermint oil for NV, does not have reliable evidence to support is efficacy.
ORS
ORS- Oral Rehydration Salt, used for dehydration associated with vomiting or diarrhea. Consists of carbohydrates, sodium, potassium, chloride, citrate. Glucose based ORS does not consist of potassium so supplementation of bananas and orange juice should be given.
Anorectal Gas
- Anorectal disorders occur in the perianal area, anal canal, and lower portion of the rectum. - Hemorrhoids are abnormally large, bulging, symptomatic conglomerates of hemorrhoidal vessels, supporting tissues, and overlying mucous membranes of skin in the anorectal region
List some Non-Hemorrhoidal anorectal disorders and can they be self treated?
Potentially serious non-hemorrhoidal anorectal disorders, including abscesses, fistulas, fissures, neoplasms, polyps, pruritus ani, and inflammatory bowel disease (IBD), may present with hemorrhoid-like symptoms and SHOULD NOT be self-treated. Patients should be referred for medical evaluation if any of the conditions are suspected
self treatable anorectal disorders
Itching (pruritus) Discomfort Irritation Burning Inflammation Swelling
Medical referal for Anorectal Disorder
-Pain - internal hemorrhoids usually painless; external hemorrhoids often cause mild pain Bleeding - hemorrhoids most common cause -Seepage- involuntary passage of fecal material or mucus caused by an anal sphincter not closed completely -Change in bowel pattern - Unexplained change in bowel frequency or in stool form; may signal serious underlying GI disorder (e.g. IBD, or colorectal cancer -Prolapse (protrusion) - protrusion of hemorrhoidal or rectal tissue of variable size into anal canal -Thrombosis (blood clotting)- associated pain is most acute during the first 48-72 hours, but usually resolves after 7-10 days. Minimal pain with thrombosed internal hemorrhoids
Exclusions for Self-Treatment for Anorectal Disorder
Anorectal disorders, including hemorrhoids, in patients <12 years Diagnosed GI diseases associated with colorectal bleeding: ulcerative colitis Crohn’s disease Family history of colon cancer Potentially serious anorectal disorder such as abscess, fistula or fissures, neoplasm or malignancy, polyps, or anorectal disorders previously diagnosed by PCP Anorectal signs or symptoms such as acute onset of severe pain; bleeding; seepage; prolapse; thrombosis; black tarry stools; and moderate-to-severe itching, burning, inflammation, swelling, and discomfort Minor anorectal symptoms that do not respond to 7 days of self-treatment
Nonpharmacologic Therapy for Anorectal Disorder
-Dietary modification -Improvement of hygiene practices -Surgical intervention -Avoid lifting heavy objects -Discontinue foods that irritate or aggravate symptoms -Increased dietary fiber or adding in fiber supplements can prevent further irritation -Proper bowel habits -Sitting in warm water in the bathtub for 10-20 min for 2-4 times/day
Local Anesthetics for anorectal disroder
- Benzocaine -Benzyl alcohol -Dibucaine -Lidocaine -Pramoxine hcl -Tetracaine Provide relief of itching, burning, discomfort, and pain by reversibly blocking transmission of nerve impulses Avoid using on open sores
Vasoconstrictors for anorectal disorder
*Ephedrine sulfate Epinephrine HCL *Phenylephrine HCL reduction of swelling/slight anesthetic effect
Skin Protectants
-*Aluminum hydroxide gel, cocoa butter, hard fat, kaotin, lanolin, mineral oil, white petrolatum, calamine, shark liver oil, zinc oxide, cod liver oil -Glycerin Provide a physical protective barrior and soften the anal canal by preventing fecal matter from irritating the perianal mucosa Glycerin is for external use only (all others are approved for internal and external) Apply to clean and dry skin
Astringents
*Calamine *Zinc Oxide Witch Hazel Promote coagulation of surface protein in the anorectal skin cells to protect the underlying tissue; decrease cell volume, drying the area; create a thin protective layer
Corticosteroids
Hydrocortisone Acts as a vasoconMay take up to 12 hours to feel effectstrictor and antipruritic -Onset of action:up to 12 hours -Duration of action: much longer than other agents
exclusion for Intestinal Gas
Nonpharmacologic Therapy for intestinal gas
Patient may benefit from changes in eating habits
- Don’t rush through a meal
- Do not overeat
- Avoid smoking
- Etc.
Patients may benefit from dietary modifications
- Keeping a dietary diary
- Avoiding foods that cause gas symptoms
- Avoid carbonated beverages, such as sodas and beer
Medication use and lifestyle habits
- Avoid long-term or frequent intermittent use of medications intended for relief of cold symptoms
- Avoid tight fitting garments, girdies, and belts
- Do not lie down or sit in the slumped position immediately after eating
- Develop a regular routine of exercise and rest
Pharmacological Therapy for intestinal gas
Simethicone, Activated Charcoal, 𝝰 Galactosidase Replacement Products, Lactase Replacement Products
Simethicone for intestinal gas
Simethicone
- Used as a defoaming agent to relieve gas
- Used in patients with acute, non specific diarrhea
- Used to treat intestinal gas AFTER it has occurred
- No side effects
- discontinue if adequate relief is not obtained within 24 hours
Activated Charcoal in terms of intestinal gas
Promoted BUT NOT approved nor shown to be effective for intestinal gas, DON’T RECOMMEND
𝝰 Galactosidase Replacement Products in terms of intestinal gas
- For use as an antiflatulent
- Recommended as a preventive treatment of intestinal gas symptoms produced by high-fiber diets of foods that contain oligosaccharides.
- Must be administered just BEFORE or with the first bite of food that causes flatus and/or bloating
- Heat can inactivate the enzyme
Lactase Replacement Products in terms of intestinal gas
- Used in patients with lactose intolerance.
- No adverse effects
- To be taken with the 1st bite of food containing dairy
- Lactase enzyme use with ages >12 years old
dosage for intestinal gas
probiotic for intestinal gas
- Used for GI complaints including intestinal gas and bloating.
- Formulated from either one bacterium or multiple bacteria
Complementary Treatments for intestinal gas
Fennel can cause photodermatitis, is contraindicated during pregnancy, and enters breast milk in lactating women. If fennel is used, patients should be advised to avoid excessive sunlight and avoid use during pregnancy and lactation. It can also lower ciprofloxacin levels
Differentiate between the clinical presentation of heartburn, gastroesophageal reflux disease (GERD), dyspepsia and peptic ulcer disease (PUD).
Contributing Factors to Heartburn
Dietary
- Fatty foods
- Spicy foods
- Chocolate
- Salt and salt substitutes
- Caffeinated or carbonated beverages
- Citrus fruits or juices
- Tomatoes/tomato juice
Lifestyle
- Exercise
- Smoking
- Obesity
- Stress
- Laying down after eating
- Tight-fitting clothing
Diseases
- Motility disorders (e.g. gastroparesis)
- Scleroderma -rare disease that causes the hardening and tightening of skin
- PUD (peptic ulcer disease)- painful sores or ulcers in the lining of the stomach
- Zollinger-Ellison syndrome- disease in which tumors cause the stomach to produce too much acid, resulting in peptic ulcers
Medications
- Bisphosphonates
- Aspirin/NSAIDs
- Iron
- Potassium
- Quinidine
- Tetracycline
- Zidovudine
- Anticholinergic agents
- Calcium channel blockers
- Alpha/Beta adrenergic agonists
- Progesterone
- Chemotherapy
Exclusion to self treatment GERD