Exam 1 Drugs Flashcards

1
Q

Plaquenil

hydroxychloroquine

A

Non-biologic DMARD

T-lymphocyte suppression

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2
Q

Arava

leflunomide

A

Non-biologic DMARD

Pyrimidine synthase inhibitor

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3
Q

Rheumatrex

methotrexate

A

Non-biologic DMARD

Dihydrofolate reductase inhibitor

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4
Q

Azulfidine

sulfasalazine

A

Non-biologic DMARD

Inhibits cytokine secretion

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5
Q

Orencia

abatacept

A

Biologic DMARD

Inhibits T-cell activation - blocks CD80/86 on APC

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6
Q

Kineret

anakinra

A

Biologic DMARD

Inhibits IL-1 receptor antagonist

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7
Q

Rituxan

rituximab

A

Biologic DMARD

Induces B-cell apoptosis - CD20 antibody; binds to CD20 on B cells

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8
Q

Actemra

tocilizumab

A

Biologic DMARD

Inhibits IL-6

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9
Q

Kevzara

sarilumab

A

Biologic DMARD

Inhibits IL-6

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10
Q

Humira

adalimumab

A

DMARD

Binds TNF-a

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11
Q

Cimzia

certolizumab

A

DMARD

Binds TNF-a

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12
Q

Enbrel

etanercept

A

DMARD

Binds TNF-a

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13
Q

Simponi

golimumab

A

DMARD

Binds TNF-a

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14
Q

Remicade

infliximab

A

DMARD

Binds TNF-a

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15
Q

Xeljanz

tofacitinib

A

DMARD

Selective JAK inhibitor

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16
Q

Olumiant

baricitinib

A

DMARD

Selective JAK inhibitor

17
Q

Rinvoq

upadacitnib

A

DMARD

Selective JAK inhibitor