Exam 1: Concepts Of Fluid & Electrolytes Applied To IV Solutions Flashcards
Interstitial
Fluid between the cells.
Transcellular Fluid
CSF, synovial fluid, intraocular fluid
Cation
Positively charged ion
Anion
Negatively charged ion
Osmosis
Movement of water from an area of low concentration to an area of high concentration
Diffusion
Movement of solutes across a membrane from an area of high concentration to an area of low concentration
Filtration
..
Colloid osmotic pressure (oncotic pressure)
Osmotic pressure caused by plasma colloids in solution; the ability for protein to attract fluid in its direction
Hydrostatic Pressure
Force of fluid in a compartment pushing against a cell membrane or vessel wall.
Antidiuretic hormone
Released by your anterior pituitary gland to the kidneys (target organ), specifically the Loop of Henie > retains water
What stimulates the release of Aldosterone?
Stimulated by high potassium. Aldosterone is then released from the adrenal glands to the kidneys (target organ), specifically to the Loop of Henle.
What are the actions of aldosterone?
Na+ and H20 reabsorption and removal of potassium through the urine.
Denim
Converts Angiotensin I (vasoconstrictor) to Angiotensin II (stimulates aldosterone)
Fluid Output Regulation
Through urine (normal 1.5 L of urine/day)
Loss of fluid through feces.
Fluid loss through sweat, breathing (600-800mL)
“-emia”
Blood
Normal Sodium Values
135-145 mEq/L
Pathophysiology of Sodium Electrolytes
Primary extracellular electrolyte; attracts fluid
Hyponatremia: What causes it?
- Diarrhea, Vomiting
- NG tube auctioning
- Diuretics
- Wound drainage
- Fasting
- Excessive hypotonic IV fluid (water, 0.45 NaCl)
Hyponatremia: Symptoms
Headache, apathy and confusion
Hyponatremia: Nursing Care
- Fluid Restriction
- Slow amount of hypertonic solution (3% NaCl)
- Vasopressant (decreased antidiuretic hormone secretion)
Hypernatremia: What causes it?
- Excess sodium intake.
- Inadequate fluid intake.
- Excess water loss.
- Increase in insensible water loss (asthma, talking)
Hypernatremia: Symptoms
- Restlessness
- Agitation
- Twitching
- Seizure
- Constant thirst
- Weight gain (d/t water retention)
- Edema (d/t water retention)
- Increased BP
Hypernatremia: Nursing Care
Water replacement: hypotonic solution (D5W, 0.45 NaCl)
Potassium Normal Lab Values
3.5 - 4.5 mEq/L
Potassium Electrolyte
Can be very harmful to the tissue (has necrotic and ischemic effect.
Pathophysiology of Potassium Electrolyte
Primarily found intracellularly
Effects neuromuscular and cardiac function; contractility of muscle
Hypokalmeia: What causes it?
- Potassium loss (diuretics, vomiting, diarrhea, adrenal tumor, hyperaldosteronism)
- Cancer (aldosterone increase)
- Dialysis
- Increase in insulin (allows cell to …)
- Low potassium in diet
Hypokalemia: Symptoms
- Skeletal muscle weakness and paralysis: respiratory muscles (shallow respiration’s and respiratory arrest); decreased airway responsiveness; decreased GI motility; impaired regulation of arterial BF -> smooth muscle cell breakdown.
- Impairs insulin secretion -> hyperglycemia
Hypokalemia: Nursing Care
- Administer potassium supplement - need to know that the patient is urinating to ensure the patient is not retaining; could lead to hyperkalemia! (Ensure that the IV is not infiltrated d/t harmful effects of potassium on tissue.
Sources of Potassium in food include
Bananas, Green leafy vegetables, ..
Hyperkalemia: What causes it?
(IM-PAID)
- Impaired renal secretion
- Massive intake
- Potassium Penicillin
- Adrenal insufficiency: low aldosterone = retention of K+
- ICF->ECF (cell lysis): Acidosis (K moves out of cell so H+ moves into cell); Massive cell destruction; Receiving old blood; decubitus ulcer
- Drugs: Digoxin & Beta adrenergic blockers (impairs entry of K into cells = increases K ECF concentration); K Sparing Diuretics and ACE inhibitors (decreases kidney ability to excrete K+)
Hyperkalemia: Symptoms
- increased cellular excitability
- cramping leg pain and weakness followed by weakness/paralysis of other skeletal muscles including respiratory.
- hyperactivity of smooth muscles = abdominal cramping & diarrhea.
- Cardiac disturbances: too much K+ causes the heart to quiver and beat fast
Hyperkalemia: Nursing Care
- Eliminate PO/IV meds
- Eliminate K: diuretics; dialysis; ion exchange resins (kayexalate -binds to K in exchange for Na and is released in feces)
- Reverse membrane potential effects: IV calcium gluconate (Ca ions reverse the membrane excitability); Withhold K from diet and IV, loop/thiazides
- IV of regular Insulin to correct acidosis
- Beta-adrenergic agonists
Fluid Volume Deficit: What causes it?
Diarrhea, vomiting, drainage
Fluid Volume Deficit: Symptoms
- Increased thirst
- Lethargy
- Confusion
- Postural Hypotension
- Decreases capillary refill
- Decreases urine output
Fluid Volume Deficit: Treatment
- Isotonic solution (0.09% NaCl, D5/Lactated Ringer, Blood Transfusion)
Fluid Volume Excess
Water and solutes are retained at the same time.
Fluid Volume Excess: What can cause it?
CHF, renal failure, burns
Fluid Volume Excess: Symptoms
- Headache
- Polyuria, polydipsia
- Weight gain, edema
- Confusion, lethargy, seizure
- Crackles
Fluid Volume Excess: Treatment
- Diuretics
- Fluid Restriction
- Sodium Restriction
Hyperosmolar
Too much concentration of certain elements (ex. Hypernatremia, hyperkalemia)
Hyposmolar
Too little concentration of certain elements (ex. Hypokalemia, hyponatremia)
What factors can affect fluid and electrolyte imbalance?
I. Age II. Illness (IBS, Chron’s, Surgery, Cancer) III. Environmental Factors IV. Diet V. Lifestyle VI. Medications
Normal CBC values
…
Common Laboratory Studies R/T fluid and electrolytes
- CBC
- ABG
- Serum Electrolytes level
Why are hematocrit levels important in relation to fluid and electrolyte balance?
High hematocrit levels could indicate the need for more fluid.
Nursing Therapeutics/Plan of Care for Patients with Fluid and Electrolyte Problems
- Daily Weight Taking
- Enteral Replacement of Fluid and Electrolyte Loss
- Fluid Restriction vs. Increase Fluid Intake
- Parenteral Replacement of Fluid and Electrolytes
- Medication
- I&O monitoring
What are the isotonic solutions that we use?
- Normal Saline
- Ringers
- Lactated Ringer’s
- Dextrose 5% in Water (D5W)
- 5% albumin
- Hetastarch
- Normosol
Though Dextrose 5% in Water is an isotonic solution
Its physiologic effect is hypotonic because when it is taken, glucose is taken up by the body for energy leaving behind only fluid.
What is a sign for right sided congestion?
Jugular venous distension
How should you assess for jugular venous distention?
The patient should be position in a 30-45 degree angle with head tilted to one side. HOWEVER, the best way to verify congestion is with the patient standing up.
Isotonic Solutions should be cautioned in what kind of patients?
- In patients with HTN and heart failure.
- LR should not be given to patients with a pH greater than 7.5
- D5W should be avoided in patients with increased ICP
Why should LR not be given to patient with a pH greater than 7.5?
LR is converted to bicarbonate in the body therefore making the blood more basic.
Why should D5W be avoided in patients with increased ICP?
Because D5W becomes physiologically hypotonic.
What are the hypotonic solutions that we use?
- Half Saline (.45% NaCl)
- 0.33% NaCl
- Dextrose 2.5% in Water (D2.5W)
Nursing Implications for Hypotonic Solutions
- Can cause vascular collapse.
- Increases ICP
- Do not give to patients at risk for ICP (CVA, neurosurgery, or patients with third spacing (blisters, burns, ascites))
What are the hypertonic solutions that we use?
- Dextrose 5% in Normal Saline
- Dextrose in Lactated Ringers
- 3% NaCl
- 25% Albumin
- 7.5% NaCl
What are the nursing implications for hypertonic solutions?
Do not give these to patient’s who have potential for cellular dehydration (e.t diabetics)
Isotonic solutions
Expands the intra-vascular compartments
Hypotonic Solutions
Will cause fluid shift from vessels to cell
Hypertonic Solutionss
Greatly expands the intra-vascular compartment, pull fluid from intracellular compartment to intravascular.
What kind of relationship does Na and K have?
Inverse relationship. When Na is retained, K is eliminated.
Normal plasma osmolality
275-295 mOsm/kg.
A plasma osmolarity of > 295 mOsm/kg indicates what?
that the concentration of particles is too great or that the water content is too = water deficit
A plasma osmolarity of < 275 mOsm/kg indicates what?
too little solute for the amount of water or too much water for the amount of solute = water excess
Antagonists to RAAS
Natriuretic peptides
How does the hypothalamus regulate water balance?
Decreased body fluid and increased plasma osmolarity is sensed by osmoreceptors in the. Hypothalamus -> stimulates thirst and ADH release (acts in kidneys = water reabsorption)
Factors that stimulates ADH release
THIRST stress Nausea Nicotine Morphine