Exam 1 Antibiotic Mechanisms Flashcards
What is the mode of action of fluoroquinolones/quinolones?***
inhibit nucleic acid synthesis by inhibiting with DNA gyrase
What is the mode of action of beta-lactams?***
inhibit cell wall synthesis (by targeting peptidoglycan synthesis)
What is the mode of action of sulfonamides and potentiated sulfas?***
interfere with DNA synthesis by blocking folic acid synthesis
What is the mode of action of tetracyclines?***
inhibit protein synthesis
What is the mode of action of aminoglycosides?
inhibit protein synthesis
What is the mode of action of lincosamides?
inhibit protein synthesis
What is the mode of action of macrolides?
inhibit protein synthesis
What is the mode of action of peptides?
inhibit cell membrane function
What is the mode of action of glycopeptides (vancomycin)?
inhibit cell wall synthesis by targeting peptidoglycan synthesis
What is the mode of action of nitroimidizoles?
inhibit repair by disrupting DNA structure
What is the mode of action of rifampins?
inhibit transcription by inhibiting DNA-dependent RNA polymerase?
What is the mode of action of nitrofurans?
inhibit protein synthesis