EXAM #1: ABNORMAL GROWTH OF PEDS Flashcards

1
Q

What is the normal weight-for-height?

A

2.3rd - 97.7th percentile

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2
Q

What are the abnormal BMIs for children?

A

Overweight: 85th-95th
Obese= 96th+
Underweight= less than 3rd

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3
Q

What causes a US/LS?

A

1) Turner Syndrome
2) Rickets
3) Achondroplasia

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4
Q

What causes a decreased US/LS?

A

Marfan Syndrome

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5
Q

What is the definition of Failure to Thrive?

A
  • Weight less than 2nd percentile
  • Decreased velocity of weight gain

*Underlying cause is INSUFFICIENT NUTRITION

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6
Q

What is the difference between wasting and stunting?

A

Wasting= low weight for height

Stunting= low height for age

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7
Q

What indicates an abnormally tall child?

A

1) Height greater than 97.7 %
2) Deviation upward 2 height % curves

*Note that mid-parental height, advanced bone age, and dysmorphic features are also indications for a problem.

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8
Q

What is bone age? How is this measurement taken?

A
  • Left hand and wrist x-ray taken and evaluated
  • Radiologist gives new age

*This number is then used as a correction in the growth plot

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9
Q

What is the most common cause of overgrowth in infancy?

A

Maternal DM

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10
Q

Aside from maternal DM, what are the two most common causes of infant overgrowth?

A

1) Sotos Syndrome

2) Beckwith-Wiedemann Syndrome

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11
Q

What is familial tall stature?

A

Simply a tall family (no pathology)

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12
Q

What is the difference between central and peripheral precocious puberty?

A

Central= neuro

Peripheral= gonad related

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13
Q

What are the symptoms of precocious puberty?

A

1) Advanced bone age
2) Early epiphyseal closure
3) Tall child that turns out to be short adult

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14
Q

What is the most reliable measurement for gigantism?

A

IGFBP-3

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15
Q

What is meant by “eunchoid proportions?”

A
  • Long legs
  • Reduced UL segment ratio
  • Low sitting height
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16
Q

What is the phenotype of melanocortin-4 receptor mutations?

A

Obesity

17
Q

What is the genetic basis for Klinefelter’s Syndrome

A

2+ X chromosomes in males

18
Q

What is the typical phenotype of a 47 XYY patient?

A

Autism-like

19
Q

What is a major clinical difference between Marfan Sydrome and Homocystinuria?

A

Marfan= lens subluxed upward

Homocystinuria= lens subluxed downward
- Also, intellectual disability

20
Q

What is the definition of a short child?

A

Height less than 2.3rd%

21
Q

How does constitutional delay differ from familial short stature?

A

Familial= short parents–kid will be short

Constitutional delay= kid just takes a long time to reach normal height

22
Q

What condition should any short girl be worked up for?

A

Turner’s Syndrome